Umirolimo - ≥95% , CAS No.851536-75-9

CAS: 851536-75-9 Cat. No.: U329293 Fórmula: C₅₅H₈₇NO₁₄ Peso molecular: 986.3 PubChem CID: 11158972

GRAU & PUREZA ≥95%

Synonyms

Umirolimus | U36PGF65JH | umirolimusum | EX-A3593 | Rapamycin, 42-O-(2-ethoxyethyl)- | TRM986 | TRM-986 | TRM 986 | 40-O-(2-ethoxyethyl)rapamycin | Q7881588 | SCHEMBL17117902 | UMIROLIMUS [USAN] | 42-O-(2-ethoxyethyl) rapamycin | Biolimus A9 | UNII-U36PGF

Storage

Armazenar a -20°C

Shipped In

Arca de gelo + almofadas de gelo

Visão geral

O umirolimus liga-se à proteína recetora, FKBP12, e depois o complexo liga-se ao mTOR e impede-o de interagir com as proteínas alvo, o que suprime as imunorreacções localizadas.

Especificações

Sinónimos

Umirolimus | U36PGF65JH | umirolimusum | EX-A3593 | Rapamycin, 42-O-(2-ethoxyethyl)- | TRM986 | TRM-986 | TRM 986 | 40-O-(2-ethoxyethyl)rapamycin | Q7881588 | SCHEMBL17117902 | UMIROLIMUS [USAN] | 42-O-(2-ethoxyethyl) rapamycin | Biolimus A9 | UNII-U36PGF

Especificações e pureza

≥95%

Fonte

Streptomyces hygroscopicus

Condições de armazenamento de armazenamento

Armazenar a -20°C

Enviado em

Arca de gelo + almofadas de gelo

Pureza

≥95%

Nomes e identificadores

Pubchem Sid

528767605

Sorrisos canónicos

CCOCCOC1CCC(CC1OC)CC(C)C2CC(=O)C(C=C(C(C(C(=O)C(CC(C=CC=CC=C(C(CC3CCC(C(O3)(C(=O)C(=O)N4CCCCC4C(=O)O2)O)C)OC)C)C)C)OC)O)C)C

IUPAC Name

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-12-[(2R)-1-[(1S,3R,4R)-4-(2-ethoxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

InChIKey

YYSFXUWWPNHNAZ-PKJQJFMNSA-N

INCHI

1S/C55H87NO14/c1-12-67-26-27-68-45-24-22-41(31-48(45)65-10)30-37(5)47-33-44(57)36(4)29-39(7)50(59)51(66-11)49(58)38(6)28-34(2)18-14-13-15-19-35(3)46(64-9)32-42-23-21-40(8)55(63,70-42)52(60)53(61)56-25-17-16-20-43(56)54(62)69-47/h13-15,18-19,29,34,36-38,40-43,45-48,50-51,59,63H,12,16-17,20-28,30-33H2,1-11H3/b15-13+,18-14+,35-19+,39-29+/t34-,36-,37-,38-,40-,41+,42+,43+,45-,46+,47+,48-,50-,51+,55-/m1/s1

SMILES isoméricas

CCOCCO[C@@H]1CC[C@H](C[C@H]1OC)C[C@@H](C)[C@@H]2CC(=O)[C@@H](/C=C(/[C@H]([C@H](C(=O)[C@@H](C[C@@H](/C=C/C=C/C=C(/[C@H](C[C@@H]3CC[C@H]([C@@](O3)(C(=O)C(=O)N4CCCC[C@H]4C(=O)O2)O)C)OC)\C)C)C)OC)O)\C)C

PubChem CID

11158972

Peso molecular

986.3

Propriedades químicas e físicas

• Solubilidade: Soluble in ethanol, methanol, DMF, and DMSO. Limited water solubility.
• Ponto de ebulição (°C): ~991.0° C at 760 mmHg (Predicted)