VH 032 amide-PEG5-acid - ≥95% , CAS No.2172820-14-1

CAS: 2172820-14-1 Cat. No.: V288765 Fórmula: C₃₆H₅₄N₄O₁₁S Peso molecular: 750.91 PubChem CID: 134184001

GRADE & PURITY ≥95%

Synonyms

ácido (S)-21-((2S,4R)-4-hidroxi-2-((4-(4-metiltiazol-5-il)benzil)carbamoil)pirrolidina-1-carbonil)-22,22-dimetil-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanóico | (S,R,S)-AHPC-PEG5-COOH | VH032-PEG5-COOH | Ligante ligante de BVS 16

Storage

Armazenar a -20°C, carregado com árgon

Shipped In

Arca de gelo + almofadas de gelo

Specifications

Sinónimos

ácido (S)-21-((2S,4R)-4-hidroxi-2-((4-(4-metiltiazol-5-il)benzil)carbamoil)pirrolidina-1-carbonil)-22,22-dimetil-19-oxo-4,7,10,13,16-pentaoxa-20-azatricosanóico | (S,R,S)-AHPC-PEG5-COOH | VH032-PEG5-COOH | Ligante ligante de BVS 16

Especificações e pureza

≥95%

Mecanismos bioquímicos e fisiológicos

Ligante funcionalizado da proteína von-Hippel-Lindau (VHL) para investigação e desenvolvimento PROTAC®; incorpora um ligante de ligase E3 mais um ligante PEG5 com ácido carboxílico terminal pronto para conjugação com um ligante de proteína alvo. Faz parte

Condições de armazenamento de armazenamento

Armazenar a -20°C, carregado com árgon

Enviado em

Arca de gelo + almofadas de gelo

Pureza

≥95%

Nomes e identificadores

Pubchem Sid

488202799

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488202799

Sorrisos canónicos

CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)C3CC(CN3C(=O)C(C(C)(C)C)NC(=O)CCOCCOCCOCCOCCOCCC(=O)O)O

IUPAC Name

3-[2-[2-[2-[2-[3-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

InChIKey

YDOJYEPMGKGKQV-ZLWRCJDJSA-N

INCHI

1S/C36H54N4O11S/c1-25-32(52-24-38-25)27-7-5-26(6-8-27)22-37-34(45)29-21-28(41)23-40(29)35(46)33(36(2,3)4)39-30(42)9-11-47-13-15-49-17-19-51-20-18-50-16-14-48-12-10-31(43)44/h5-8,24,28-29,33,41H,9-23H2,1-4H3,(H,37,45)(H,39,42)(H,43,44)/t28-,29+,33-/m1/s1

PubChem CID

134184001

Peso molecular

750.91

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2172820-14-1, the molecular formula is C36H54N4O11S, and the molecular weight is 750.91 g/mol. InChIKey YDOJYEPMGKGKQV-ZLWRCJDJSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.