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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque YM-58483 (BTP2） - Moligand™, 10mM in DMSO , Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4, CAS No.223499-30-7, Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | IDI1_018066 | XPRZIORDEVHURQ-UHFFFAOYSA-N | A16346 | EX-A2467 | A910597 | GTPL2438 | btp2 | BTP-2 | CRAC Channel Inhibitor, BTP2 - CAS 2234
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Specifications Sinónimos
HMS3648I22 | AS-16763 | CRAC Channel Inhibitor, BTP2 | SR-01000644222-3 | NCGC00344111-03 | AC-35791 | HMS3886H10 | IDI1_018066 | XPRZIORDEVHURQ-UHFFFAOYSA-N | A16346 | EX-A2467 | A910597 | GTPL2438 | btp2 | BTP-2 | CRAC Channel Inhibitor, BTP2 - CAS 2234
Especificações e pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos e fisiológicos
Store-operated Ca 2+ entry blocker. Potent, selective CRAC channel inhibitor. Inhibits thapsigargin-induced sustained Ca 2+ influx (IC 50 = 100 nM). Suppresses cytokine production. Potent T-cell antiproliferative agent (IC 50 = 12.7 nM).
Condições de armazenamento de armazenamento
Store at -80°C
Enviado em
Dry ice packs + Cold packs
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
ACTIVATOR, CHANNEL BLOCKER
Mecanismo de ação
Channel blocker of TRPC3;Channel blocker of TRPC5;Activator of TRPM4
Nomes e identificadores Sorrisos canónicos
CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
IUPAC Name
N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
InChIKey
XPRZIORDEVHURQ-UHFFFAOYSA-N
INCHI
1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
SMILES isoméricas
CC1=C(SN=N1)C(=O)NC2=CC=C(C=C2)N3C(=CC(=N3)C(F)(F)F)C(F)(F)F
CAS alternativo
223499-30-7
Termos de entrada MeSH
4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide;BTP2 cpd;YM 58483;YM-58483
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Classe Benzene and substituted derivatives Subclass Anilides Intermediate Tree Nodes Not available Direct Parent Aromatic anilides Alternative Parents Phenylpyrazoles 2-heteroaryl carboxamides Thiadiazoles Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Alkyl fluorides Molecular Framework Aromatic heteromonocyclic compounds Substituents Aromatic anilide - Phenylpyrazole - 2-heteroaryl carboxamide - Azole - Pyrazole - Heteroaromatic compound - Thiadiazole - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Alkyl fluoride - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Alkyl halide - Aromatic heteromonocyclic compound Descrição This compound belongs to the class of organic compounds known as aromatic anilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with an aromatic group. They have the general structure RNC(=O)R', where R= benzene, and R = aryl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Ponto de fusão (°C) 165-167 °C Peso molecular 421.300 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 11 Rotatable Bond Count 3 Exact Mass 421.043 Da Monoisotopic Mass 421.043 Da Topological Polar Surface Area 101.000 Ų Heavy Atom Count 28 Formal Charge 0 Complexity 568.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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