1,4-Piperazinediethanesulfonic acid(PIPES) - ≥99% , CAS No.5625-37-6

CAS: 5625-37-6 Cat. No.: P105090 Peso molecular: 302.37 Beilstein Registry Number: 817713 Número EC: 227-057-6

GRADE & PURITY ≥99%

Synonyms

FT-0635789 | G502H79V6L | NCGC00164485-01 | 2,2'-piperazine-1,4-diylbisethanesulfonic acid | 2-[(2-aminoacetyl)-methylamino]acetic acid | NSC157117 | NSC-157117 | 2,2'-(Piperazine-1,4-diyl)diethanesulfonicacid | CHEBI:44933 | AS-12650 | 3,9-bis(2,4-ditert

Storage

Room temperature

Shipped In

Normal

Descripción general

PIPES [piperazine-N,N′-bis(2-ethanesulfonic acid)] is frequently used as a buffering agent in biochemistry. It is an ethanesulfonic acid buffer developed by Good et al. in the 1960s. PIPES has a pKa near the physiological pH which makes it useful in cell culture work. It has been documented to minimize lipid loss when buffering glutaraldehyde histology in plant and animal tissues.
A buffering agent with a pKa near physiological pH.

Specifications

Sinónimos

FT-0635789 | G502H79V6L | NCGC00164485-01 | 2, 2'-piperazine-1, 4-diylbisethanesulfonic acid | 2-[(2-aminoacetyl)-methylamino]acetic acid | NSC157117 | NSC-157117 | 2, 2'-(Piperazine-1, 4-diyl)diethanesulfonicacid | CHEBI:44933 | AS-12650 | 3, 9-bis(2, 4-ditert

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Buffer. Working pH range in aqueous solution: 6.1 - 7.5. Recommended for use in solutions containing metal ions. Commonly used in cell culture media, protein crystalization and gel eletrophoresis.

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
• IUPAC Name: 2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonic acid
• InChIKey: IHPYMWDTONKSCO-UHFFFAOYSA-N
• INCHI: 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
• Isómeros SMILES: C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)O
• WGK Alemania: 3
• Peso molecular: 302.37
• Beilstein: 817713
• Reaxy-Rn: 817713
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=817713&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Diazinanes
      • Subclass Piperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: Not available
• Direct Parent: N-alkylpiperazines
• Alternative Parents: Sulfonyls Organosulfonic acids Alkanesulfonic acids Trialkylamines Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: N-alkylpiperazine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tertiary amine - Tertiary aliphatic amine - Azacycle - Amine - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organosulfur compound - Organonitrogen compound - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as n-alkylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an alkyl group.
• External Descriptors: PIPES

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Solvent:1M NaOH, Max Conc. mg/mL: 151.2, Max Conc. mM: 500
• Punto de fusión (°C): ＞300°C
• Peso molecular: 302.400 g/mol
• XLogP3: -6.700
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 302.061 Da
• Monoisotopic Mass: 302.061 Da
• Topological Polar Surface Area: 132.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 397.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

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