1-Chloro-3-nitrobenzene - CP, ≥98% , CAS No.121-73-3

CAS: 121-73-3 Cat. No.: C100472 Peso molecular: 157.55 Beilstein Registry Number: 1907947 Número EC: 204-496-1
Disponible para pedir
GRADE & PURITY CP ? Chemically Pure grade — moderate purity above technical grade but below analytical. Use for general lab reactions where ultra-low impurities aren't critical. ≥98%
Synonyms
BENZENE, 1-CHLORO-3-NITRO- | DTXSID4021971 | 1-Chloro-3-nitrobenzene, 95% | 1-Nitro-3-chlorobenzene | Chloronitrobenzenes meta or para, solid [UN1578] [Poison] | 1-Chloro-3-nitrobenzene, analytical standard | Metachloronitrobenzene | meta-chloronitrobenz
Storage
Room temperature
Shipped In
FedEx DG Service
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
25g
C100472-25g
10
15,90US$
100g
C100472-100g
≥10
26,90US$
500g
C100472-500g
2
77,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

CP, ≥98% CP for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships FedEx DG Service Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
BENZENE, 1-CHLORO-3-NITRO- | DTXSID4021971 | 1-Chloro-3-nitrobenzene, 95% | 1-Nitro-3-chlorobenzene | Chloronitrobenzenes meta or para, solid [UN1578] [Poison] | 1-Chloro-3-nitrobenzene, analytical standard | Metachloronitrobenzene | meta-chloronitrobenz
Especificaciones y pureza
CP, ≥98%
Condiciones de almacenamiento de almacenamiento
Room temperature
Enviado en
FedEx DG Service
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
CP
Pureza
≥98%
Nombres e identificadores
Pubchem Sid488180813
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180813
Sonrisas canónicasC1=CC(=CC(=C1)Cl)[N+](=O)[O-]
IUPAC Name1-chloro-3-nitrobenzene
InChIKeyKMAQZIILEGKYQZ-UHFFFAOYSA-N
INCHI1S/C6H4ClNO2/c7-5-2-1-3-6(4-5)8(9)10/h1-4H
Isómeros SMILES C1=CC(=CC(=C1)Cl)[N+](=O)[O-]
WGK Alemania 3
RTECS CZ0940000
Número ONU 1578
Grupo de embalaje II
Peso molecular 157.55
Beilstein 1907947
Reaxy-Rn 1907947
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1907947&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassNitrobenzenes
Intermediate Tree Nodes Not available
Direct ParentNitrobenzenes
Alternative Parents Nitroaromatic compounds  Chlorobenzenes  Aryl chlorides  Propargyl-type 1,3-dipolar organic compounds  Organic oxoazanium compounds  Organopnictogen compounds  Organonitrogen compounds  Organochlorides  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Nitrobenzene - Nitroaromatic compound - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - C-nitro compound - Organic nitro compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organic oxoazanium - Organic nitrogen compound - Organochloride - Organohalogen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group.
External Descriptors C-nitro compound
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeFechaArticulo
K2420289Certificate of AnalysisMay 07, 2024 C100472
K2420291Certificate of AnalysisMay 07, 2024 C100472
E2011093Certificate of AnalysisMar 14, 2024 C100472
D1417001Certificate of AnalysisJan 03, 2024 C100472
C2309358Certificate of AnalysisFeb 24, 2023 C100472
C2309359Certificate of AnalysisFeb 24, 2023 C100472
C2309360Certificate of AnalysisFeb 24, 2023 C100472
D2518083Certificate of AnalysisFeb 24, 2023 C100472
E1522130Certificate of AnalysisJan 06, 2023 C100472
Propiedades químicas y físicas
SolubilidadSoluble in hot ethanol, chloroform, ether, carbon disulfide and glacial acetic acid, slightly soluble in cold ethanol, insoluble in water
Punto de inflamación (°F)255.2 °F
Punto de inflamación (°C)124 °C
Punto de ebullición (°C)236°C
Punto de fusión (°C)46°C
Peso molecular157.550 g/mol
XLogP32.500
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass156.993 Da
Monoisotopic Mass156.993 Da
Topological Polar Surface Area45.800 Ų
Heavy Atom Count10
Formal Charge0
Complexity134.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Hongbo Yu, Shuibo Wang, Lin Zhu, Chunzheng Wu.  (2023)  One-pot synthesis of Pt@Sn core-shell nanocatalysts for the hydrogenation of halonitrobenzene to produce haloaniline with ultra-high selectivity.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2023.158729]
2. Jiasheng Wang, Ying Zhang, Xiaonan Xu, Ming Bao.  (2023)  Oxygen Vacancy-Rich Ni–CeO2 Heterojunction Catalyst for Hydrogenating Halogenated Nitroarenes with High Activity and Selectivity.  ACS Applied Materials & Interfaces,      [PMID:36637974] [10.1021/acsami.2c21272]
3. Ziqi Sun, Meiling Qi.  (2022)  High separation performance of carbon dioxide-based poly(ether-carbonate) copolymer for gas chromatographic analyses.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:36166885] [10.1016/j.chroma.2022.463493]
4. Fan Yang, Hongbo Yu, Chunzheng Wu, Shiwei Wang, Tong Li, Hongfeng Yin.  (2022)  RhCu Bimetallic Nanoparticles in Hollow Carbon Spheres for Catalytic Halonitrobenzene Chemoselective Hydrogenation.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.2c02358]
5. Yebin Zhou, Ling Li, Yi Liu, Hongzheng Wang, Zhenlong Feng, Feng Feng, Qunfeng Zhang, Wucan Liu, Wenfeng Han, Chunshan Lu, Xiaonian Li.  (2022)  Palladium Nanoparticles Inset into the Carbon Sphere with Robust Acid Resistance for Selective Hydrogenation of Chloronitrobenzene.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.1c04983]
6. Hongbo Yu, Chunzheng Wu, Shiwei Wang, Tong Li, Hongfeng Yin.  (2021)  Transition Metal Oxide-Modified Ir Nanoparticles Supported on SBA-15 Silica for Selective Hydrogenation of Substituted Nitroaromatics.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.1c01164]
7. Peng Zhang, Shaonan Xu, Yan Wang, Wei Zhang, Wenqing Li, Cundi Wei, Peiping Zhang, Shiding Miao.  (2021)  Fabrication of Pd/Mg2P2O7 via a Struvite-Template Way from Wastewater and Application as Chemoselective Catalyst in Hydrogenation of Nitroarenes.  CHEMISTRY-A EUROPEAN JOURNAL,  27  (41): (10666-10676).  [PMID:34009699] [10.1002/chem.202100684]
8. Zechen Liang, Mingkai Zhang, Sai Zhang, Yongquan Qu.  (2021)  Electron-Enriched Pd Nanoparticles for Selective Hydrogenation of Halonitrobenzenes to Haloanilines.  Catalysts,  11  (5): (543).  [PMID:] [10.3390/catal11050543]
9. Wei Lang, Gengjinsheng Cheng, Rongpeng Peng, Qian-Yong Cao.  (2021)  Rhodamine-anchored poly(norbornene) for fluorescent sensing of ATP.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2021.109245]
10. Pengchao Chen, Kaijie Li, Peijian Yan, Junyou Wang, Shenghu Zhou.  (2021)  Pd–FexOy Hybrid Nanoparticles Encaged Hollow Mesoporous Silica Nanoreactors for Reduction of Nitroarenes to Aminoarenes.  Journal of Physical Chemistry C,      [PMID:] [10.1021/acs.jpcc.0c11161]
11. Yingzhang Shi, Huan Wang, Zhiwen Wang, Taikang Wu, Yujie Song, Binbin Guo, Ling Wu.  (2020)  Pt decorated hierarchical Sb2WO6 microspheres as a surface functionalized photocatalyst for the visible-light-driven reduction of nitrobenzene to aniline.  Journal of Materials Chemistry A,  (36): (18755-18766).  [PMID:] [10.1039/D0TA06099B]
12. Xue Xiong, Meiling Qi.  (2020)  A novel column fabrication approach for capillary gas chromatography via a cross-linked organogel network with high stability and inertness.  NEW JOURNAL OF CHEMISTRY,  44  (25): (10621-10627).  [PMID:] [10.1039/D0NJ02185G]
13. Yueling Cao, Kangkai Liu, Chen Wu, Hepeng Zhang, Qiuyu Zhang.  (2020)  In situ-formed cobalt embedded into N-doped carbon as highly efficient and selective catalysts for the hydrogenation of halogenated nitrobenzenes under mild conditions.  APPLIED CATALYSIS A-GENERAL,      [PMID:] [10.1016/j.apcata.2020.117434]
14. Qiuyang Zhang, Caiyun Xu, Hongfeng Yin, Shenghu Zhou.  (2019)  Enhanced Catalytic Hydrogenation Performance of Rh-Co2O3 Heteroaggregate Nanostructures by in Situ Transformation of Rh@Co Core–Shell Nanoparticles.  ACS Omega,      [PMID:31858069] [10.1021/acsomega.9b03340]
15. Hongbo Yu, Weiqiang Tang, Kaijie Li, Shuangliang Zhao, Hongfeng Yin, Shenghu Zhou.  (2019)  Enhanced Catalytic Performance for Hydrogenation of Substituted Nitroaromatics over Ir-Based Bimetallic Nanocatalysts.  ACS Applied Materials & Interfaces,      [PMID:30674185] [10.1021/acsami.8b19056]
16. Hongbo Yu, Weiqiang Tang, Kaijie Li, Hongfeng Yin, Shuangliang Zhao, Shenghu Zhou.  (2018)  Design of Cu-based intermetallic nanocrystals for enhancing hydrogenation selectivity.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2018.11.024]
17. Dongxing Zhen, Gaohong He, Xinlong Xu, Xiaoming Yan, Naixu Du, Xue Gong, Tiantian Li, Yan Dai, Xuemei Wu.  (2018)  Simultaneous enhancement of proton conductivity and methanol resistance of sulfonated poly(phthalazinone ether sulfone ketone)/superacid sulfated zirconia composite membranes for direct methanol fuel cells.  JOURNAL OF APPLIED POLYMER SCIENCE,  135  (42): (46758).  [PMID:] [10.1002/app.46758]
18. Yanlong Chen, Wenfen Zhang, Yanhao Zhang, Zhifen Deng, Wenjie Zhao, Huifang Du, Xue Ma, Dan Yin, Fuwei Xie, Yu Chen, Shusheng Zhang.  (2018)  In situ preparation of core–shell magnetic porous aromatic framework nanoparticles for mixed–mode solid–phase extraction of trace multitarget analytes.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:29735279] [10.1016/j.chroma.2018.04.039]
19. Miaomiao Liu, Weiqiang Tang, Zhaohui Xie, Hongbo Yu, Hongfeng Yin, Yisheng Xu, Shuangliang Zhao, Shenghu Zhou.  (2017)  Design of Highly Efficient Pt-SnO2 Hydrogenation Nanocatalysts using Pt@Sn Core–Shell Nanoparticles.  ACS Catalysis,      [PMID:] [10.1021/acscatal.6b03109]
20. Xinhuan Lu, Yang chen, Zhenshuang Zhao, Hao Deng, Dan Zhou, Changcheng Wei, Renfeng Nie, Qinghua Xia.  (2016)  Highly selective one-step hydrogenation of nitrobenzene to cyclohexylamine over the supported 10% Ni/carbon catalysts doped with 3‰ Rh.  RSC Advances,  (19): (15354-15361).  [PMID:] [10.1039/C5RA27202E]
21. Liu Wen-na, Fan Jun, Lin Chun, Zheng Sheng-run, Zhang Wei-guang.  (2014)  Synthesis of a New Cyclosporine-based Stationary Phase and Separation Behaviors toward Aromatic Positional Isomers by High-Performance Liquid Chromatography.  JOURNAL OF CHROMATOGRAPHIC SCIENCE,  53  (4): (548-553).  [PMID:25038034] [10.1093/chromsci/bmu083]
22. Junhua Kuang, Shuaishuai Zhang, Jia Yu, Yuting Zhang, Chun-Kuo Peng, Chen Zou, Jiaran Li, Li Peng, Lu Lin, Yan-Gu Lin, Pengbo Lyu, Shuliang Yang, Jian-Feng Li.  (2024)  Atomically dispersed iron sites from eco-friendly microbial mycelium as highly efficient hydrogenation catalyst.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39395221] [10.1016/j.jcis.2024.09.250]
23. Qianxi Wang, Yuyu Dai, Xueli Hong, Yunyang Hong, Rui Zhang, Xinhuan Yan.  (2024)  Facile preparation of Co/C catalysts encapsulated in carbon and selective hydrogenation in nitroaromatic hydrocarbons.  NEW JOURNAL OF CHEMISTRY,  48  (17): (7639-7645).  [PMID:] [10.1039/D4NJ00858H]
24. Zitao Shen, Zhuo Wang, Pengfei Ye, Lihong Guo, Sheng Peng, Yuefan Liu, Yongsheng Cui, Juan Zheng, Gangfeng Ouyang.  (2025)  Highly hydrophobic calixarene polymers for efficient enrichment of polar nitrobenzene compounds.  TALANTA,      [PMID:39778492] [10.1016/j.talanta.2025.127555]
25. Jia Xu, Tao Li, Wei E. Huang, Ning-Yi Zhou.  (2024)  Semi-rational design of nitroarene dioxygenase for catalytic ability toward 2,4-dichloronitrobenzene.  APPLIED AND ENVIRONMENTAL MICROBIOLOGY,      [PMID:38709097] [10.1128/aem.01436-23]
26. Mingyuan Jian, Kecan Dou, Deqiong Xie, Gaomei Tu, Weidong Zhu, Fumin Zhang.  (2024)  Synthesis of MXene supported Co nanoparticle catalyst for efficient catalytic transfer hydrogenation of nitro compounds with formic acid.  NEW JOURNAL OF CHEMISTRY,      [PMID:] [10.1039/D3NJ05864F]
27. Tian Zhengbin, Deng Xiaohui, He Ping, Wang Guang-Hui.  (2022)  Atomic Pt anchored on hierarchically porous monolithic carbon nanowires as high-performance catalyst for liquid hydrogenation.  Nano Research,  16  (4): (5880-5886).  [PMID:] [10.1007/s12274-022-5118-4]
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30. Jiayi Li, Shiwei Wang, Zhihao Yu, Haojian Zhang, Lin Zhu, Chunzheng Wu, Hongbo Yu.  (2025)  Catalytic Enhancement Through Interfacial Engineering: Ir-MoOx Nanocrystals on Silica for Nitroaromatic Hydrogenation.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.5c00455]
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