Determine the necessary mass, volume, or concentration for preparing a solution.
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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature,Desiccated,Cool Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 18 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 504753673 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504753673 |
| Sonrisas canónicas | CN1CCNCC1 |
| IUPAC Name | 1-methylpiperazine |
| InChIKey | PVOAHINGSUIXLS-UHFFFAOYSA-N |
| INCHI | 1S/C5H12N2/c1-7-4-2-6-3-5-7/h6H,2-5H2,1H3 |
| Isómeros SMILES | CN1CCNCC1 |
| WGK Alemania | 2 |
| RTECS | TM1225000 |
| Número ONU | 2734 |
| Grupo de embalaje | II |
| Peso molecular | 100.16 |
| Beilstein | 102724 |
| Reaxy-Rn | 102724 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=102724&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Diazinanes |
| Subclass | Piperazines |
| Intermediate Tree Nodes | N-alkylpiperazines |
| Direct Parent | N-methylpiperazines |
| Alternative Parents | Trialkylamines Dialkylamines Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | N-methylpiperazine - Tertiary aliphatic amine - Tertiary amine - Azacycle - Secondary amine - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Amine - Aliphatic heteromonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as n-methylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries a methyl group. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Apr 07, 2026 | M108683 | |
| Certificate of Analysis | Apr 07, 2026 | M108683 | |
| Certificate of Analysis | Apr 07, 2026 | M108683 | |
| Certificate of Analysis | Apr 07, 2026 | M108683 | |
| Certificate of Analysis | Jun 09, 2025 | M108683 | |
| Certificate of Analysis | Jun 06, 2025 | M108683 | |
| Certificate of Analysis | Jun 06, 2025 | M108683 | |
| Certificate of Analysis | Jun 06, 2025 | M108683 | |
| Certificate of Analysis | Jun 06, 2025 | M108683 | |
| Certificate of Analysis | Jun 06, 2025 | M108683 | |
| Certificate of Analysis | Apr 03, 2025 | M108683 | |
| Certificate of Analysis | Apr 03, 2025 | M108683 | |
| Certificate of Analysis | Sep 07, 2024 | M108683 | |
| Certificate of Analysis | Sep 07, 2024 | M108683 | |
| Certificate of Analysis | Sep 07, 2024 | M108683 | |
| Certificate of Analysis | Sep 07, 2024 | M108683 | |
| Certificate of Analysis | Nov 07, 2023 | M108683 | |
| Certificate of Analysis | Nov 07, 2023 | M108683 | |
| Certificate of Analysis | Nov 07, 2023 | M108683 | |
| Certificate of Analysis | Nov 07, 2023 | M108683 | |
| Certificate of Analysis | Oct 28, 2022 | M108683 | |
| Certificate of Analysis | Oct 26, 2022 | M108683 | |
| Certificate of Analysis | Oct 26, 2022 | M108683 | |
| Certificate of Analysis | Oct 10, 2022 | M108683 | |
| Certificate of Analysis | Oct 10, 2022 | M108683 | |
| Certificate of Analysis | Jul 21, 2022 | M108683 | |
| Certificate of Analysis | Jul 21, 2022 | M108683 | |
| Certificate of Analysis | Jul 21, 2022 | M108683 | |
| Certificate of Analysis | Jul 21, 2022 | M108683 |
| Solubilidad | Solubility in water: Completely miscible |
|---|---|
| Sensibilidad | Hygroscopic |
| Índice de refracción | 1.4655 |
| Punto de inflamación (°F) | 107.6℉ |
| Punto de inflamación (°C) | 42℃ |
| Punto de ebullición (°C) | 138°C |
| Punto de fusión (°C) | -6.4°C |
| Peso molecular | 100.160 g/mol |
| XLogP3 | -0.400 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 100.1 Da |
| Monoisotopic Mass | 100.1 Da |
| Topological Polar Surface Area | 15.300 Ų |
| Heavy Atom Count | 7 |
| Formal Charge | 0 |
| Complexity | 48.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yuhao Han, Xinyan Qu, Haoyuan Geng, Lei Wang, Zihan Zhu, Yaqi Zhang, Xiaoqing Cui, Heng Lu, Xiao Wang, Panpan Chen, Quanbo Wang, Chenglong Sun. (2023) Isotope-Coded On-Tissue Derivatization for Quantitative Mass Spectrometry Imaging of Short-Chain Fatty Acids in Biological Tissues. ANALYTICAL CHEMISTRY, [PMID:37997359] [10.1021/acs.analchem.3c03308] |
| 2. Song Wang, Yan Wang, Yanchao Zhang, Zhiyan Sui, Junjian Yu, Jialin Zhao, Na Li, Yifang Chang, Di Liu, Zhe Wang. (2023) Synergistic interaction and alkali resistance of N-spirocyclic cations with piperidine cations for poly(biphenyl piperidine) membranes. JOURNAL OF MEMBRANE SCIENCE, [PMID:] [10.1016/j.memsci.2023.121986] |
| 3. D.-Y. Li, Y.-H. Liu, Q. Wang, X.-W. Lei, C.-Y. Yue, Z.-H. Jing. (2023) Zero-dimensional hybrid zinc halides with blue light emissions. Materials Today Chemistry, [PMID:] [10.1016/j.mtchem.2023.101604] |
| 4. Ke Wang, Liru An, Ganghui Lu, Jialu Zhang, Zilong Wang, Meiyu Si, Guiyan Liu, Yongfei Zeng. (2023) Effect of heterocyclic substituents on the thermo/pH/CO2-responsiveness of multistimuli-responsive homopolymers. POLYMER, [PMID:] [10.1016/j.polymer.2023.126039] |
| 5. Yihao Chen, Lei Zhou, Shuigen Zhou, Donghui You, Haizhou Xiong, Yuhan Hu, Qinlin Chen, Rongxing He, Ming Li. (2023) Effect of the Host Lattice Environment on the Expression of 5s2 Lone-Pair Electrons in a 0D Bismuth-Based Metal Halide. INORGANIC CHEMISTRY, [PMID:36716166] [10.1021/acs.inorgchem.2c03961] |
| 6. Nan He, Pifu Gong, Xingyu Zhang, Youquan Liu, Linfeng Dong, Zheshuai Lin. (2023) (C5N2H14)GeBr4: A 2D Organic Germanium Bromide Perovskite with Strong Orange Photoluminescence Properties. INORGANIC CHEMISTRY, [PMID:36602526] [10.1021/acs.inorgchem.2c03432] |
| 7. Lihua Zhou, Yang He, Shaohua Gou, Qin Zhang, Ling Liu, Lan Tang, Xianzhi Zhou, Ming Duan. (2019) Efficient inhibition of montmorillonite swelling through controlling flexibly structure of piperazine-based polyether Gemini quaternary ammonium salts. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.123190] |
| 8. Yugui Han, Yefei Wang, Xianghai Meng, Qiuxia Wang, Xiaodong Han. (2019) Wormlike micelles with a unique ladder shape formed by a C22-tailed zwitterionic surfactant bearing a bulky piperazine group. Soft Matter, 15 (38): (7644-7653). [PMID:31486473] [10.1039/C9SM01358J] |
| 9. Dongdong Yao, Ting Li, Yaping Zheng, Zhilin Zhang. (2019) Fabrication of a functional microgel-based hybrid nanofluid and its application in CO2 gas adsorption. REACTIVE & FUNCTIONAL POLYMERS, [PMID:] [10.1016/j.reactfunctpolym.2018.12.025] |
| 10. Fei Liu, Mengxiang Fang, Wenfeng Dong, Tao Wang, Zhixiang Xia, Qinhui Wang, Zhongyang Luo. (2018) Carbon dioxide absorption in aqueous alkanolamine blends for biphasic solvents screening and evaluation. APPLIED ENERGY, [PMID:] [10.1016/j.apenergy.2018.10.007] |
| 11. Zhao Yingyuan, Li Xiyou. (2013) Aggregation behavior of naphthalimide fluorescent surfactants in aqueous solution. COLLOID AND POLYMER SCIENCE, 292 (3): (687-698). [PMID:] [10.1007/s00396-013-3100-0] |
| 12. Wenjun Fang, Dongbei Shao, Xiaoxing Lu, Yongsheng Guo, Li Xu. (2012) Extraction of Aromatics from Hydrocarbon Fuels Using N-Alkyl Piperazinium-Based Ionic Liquids. ENERGY & FUELS, [PMID:] [10.1021/ef201955n] |
| 13. Yuchao Li, Nan He, Bohui Xu, Linfeng Dong, Xingyu Zhang, Jing Xu, Pifu Gong, Zheshuai Lin. (2024) Synthesis, Structure, and Optical Properties of a 0D Hybrid Organic–Inorganic Metal Halide (C5N2H14Cl)GeCl3. INORGANIC CHEMISTRY, [PMID:38381086] [10.1021/acs.inorgchem.4c00091] |
| 14. Xiaoqian Jiang, Aihua Qu, Xinxin Xu, Hua Kuang, Liqiang Liu, Chuanlai Xu. (2024) Ultrasensitive detection of imatinib in human serum using a gold-based paper sensor. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, [PMID:38281369] [10.1016/j.jchromb.2024.124001] |
| 15. Hongyuan Yan, Fang Wang, Dandan Han, Gengliang Yang. (2012) Simultaneous determination of four plant hormones in bananas by molecularly imprinted solid-phase extraction coupled with high performance liquid chromatography. ANALYST, 137 (12): (2884-2890). [PMID:22553770] [10.1039/C2AN35362H] |
| 16. Juxiang Ruan, Xiongjun Zuo, Qiwei Lang, Zhijian Zeng, Chao Li. (2013) Preparation of a dibenzylated 1,4-diazacyclohexane-derived strong anion-exchange stationary phase. JOURNAL OF CHROMATOGRAPHY A, [PMID:23721810] [10.1016/j.chroma.2013.04.050] |
| 17. Yan Yan, Pengchong Wang, Ruiying Li, Ying Sun, Rui Zhang, Chuanchuan Huo, Jianfeng Xing, Yalin Dong. (2019) Synthesis of budesonide conjugates and their anti-inflammatory effects: a preliminary study. Drug Design Development and Therapy, [PMID:30858698] [10.2147/DDDT.S192348] |
| 18. Lilei zhang, Ning Ma, Lin Xie, Ye Wang, Yinchao Fan, Zhiyan Xu, Jingxiao Zhang. (2025) Density, speed of sound, refractive index, and hydrogen bonding network in the binary system of N-Methylpiperazine and ethanolamine. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2025.128726] |