10,11-Dihydro-10-Hydroxycarbamazepine - ≥97% , CAS No.29331-92-8

CAS: 29331-92-8 Cat. No.: H303342 Peso molecular: 254.29 Número EC: 608-350-1

GRADE & PURITY ≥97%

Synonyms

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE | racemic 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide | 10-Hydroxy-10,11-dihydro-dibenzo[b,f]azepine-5-carboxylic acid amide | XFX1A5KJ3V | ( inverted exclamation markA)-10-Hydroxy-10,11-dihydro-5H-dib

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Specifications

Sinónimos

10, 11-DIHYDRO-10-HYDROXYCARBAZEPINE | racemic 10-hydroxy-10, 11-dihydro-5H-dibenzo[b, f]azepine-5-carboxamide | 10-Hydroxy-10, 11-dihydro-dibenzo[b, f]azepine-5-carboxylic acid amide | XFX1A5KJ3V | ( inverted exclamation markA)-10-Hydroxy-10, 11-dihydro-5H-dib

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

Active metabolite of oxcarbazepine . Induces microsomal enzymes via sodium channel protein inhibition. Potentiates minor GABA A receptor currents; exhibits anticonvulsant activity. Antiepileptic agent. Active in vivo .

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥97%

Nombres e identificadores

• Pubchem Sid: 504756721
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504756721
• Sonrisas canónicas: C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O
• IUPAC Name: 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
• InChIKey: BMPDWHIDQYTSHX-UHFFFAOYSA-N
• INCHI: 1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
• Isómeros SMILES: C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O
• Peso molecular: 254.29
• Reaxy-Rn: 1540211
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1540211&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Benzazepines
      • Subclass Dibenzazepines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Benzazepines
• Subclass: Dibenzazepines
• Intermediate Tree Nodes: Not available
• Direct Parent: Dibenzazepines
• Alternative Parents: Azepines Benzenoids Secondary alcohols Isoureas Azacyclic compounds Organopnictogen compounds Imines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Dibenzazepine - Azepine - Benzenoid - Isourea - Secondary alcohol - Carboximidic acid derivative - Azacycle - Alcohol - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Imine - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dibenzazepines. These are compounds with two benzene rings connected by an azepine ring. Azepine is an unsaturated seven-member heterocycle with one nitrogen atom replacing a carbon atom.
• External Descriptors: carboxamide - dibenzooxazepine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

Discover Target: HTR2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

P2RX4 Tchem P2X purinoceptor 4 (516 Activities)

Discover Target: P2RX4

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Homo sapiens (32628 Activities)

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Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Scn8a Sodium channel protein type VIII alpha subunit (53 Activities)

Discover Target: Scn8a

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Rattus norvegicus (775804 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Punto de inflamación (°C): 214.6°C
• Punto de ebullición (°C): 431.3°C at 760 mmHg
• Peso molecular: 254.280 g/mol
• XLogP3: 1.400
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 254.106 Da
• Monoisotopic Mass: 254.106 Da
• Topological Polar Surface Area: 66.600 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 347.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1