α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens, CAS No.9001-67-6

CAS: 9001-67-6 Cat. No.: N755087 Número EC: 232-624-6

GRADE & PURITY Proteomics grade, suitable for MALDI-TOF MS

Descripción general

Neuraminidase is an important deglycosylation enzyme capable of cleaving all non-reducing unbranched N-acetylneuraminic and N-glycolylneuraminic acid residues by hydrolysis of α(2→6), α(2→3), α(2→8), and α(2→9) linkages (affinity in the order given). Branched sialic acids may also be cleaved with the use of high concentrations of enzyme and prolonged incubations. Desialylated glycoproteins may then be further characterized by treatment with various exoglycosidases resulting in partial or complete O-deglycosylation. SDS-PAGE and MALDI-TOF MS are typically utilized in purification, structural analysis, and sequencing process. These techniques also remove heterogeneity and charge from the glycoprotein.

Specifications

Product Name

α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens, CAS No.9001-67-6

Grado

Proteomics grade

Especificaciones y pureza

Proteomics grade, suitable for MALDI-TOF MS

CAS

9001-67-6

Número de la Comisión de Enzimas

3.2.1.18(BRENDA, IUBMB)

Tipo de molécula

Enzyme

Almacenamiento y envío

Concentración

suitable for MALDI-TOF MS

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Referencias

1. Qian Wang, Zichao Peng, Bin Gui, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang, Libo He.  (2025)  Sialic acid serves as a functional receptor for grass carp reovirus.  PLoS Pathogens,  21  (9): (e1013481).  [PMID:40911632] [10.1371/journal.ppat.1013481]

2. Yifei Wang, Mengyi Zhang, Yimeng An, Lanshu Li, Hao Wu, Ziqi Cheng, Ling Pan, Chaoying Yang, Weijin Huang, Yansheng Geng, Chenyan Zhao.  (2025)  A Bioluminescent Imaging Mouse Model for Seasonal Influenza Virus Infection Based on a Pseudovirus System.  Viruses-Basel,  17  (5): (686).  [PMID:40431697] [10.3390/v17050686]