Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AR, ≥98%(HPLC) AR for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 138 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
2,4-Dinitrophenylhydrazine (DNPH), a hydrazine derivative, is a potential mutagenic agent. Its molecular and crystal structure has been analyzed. The intra- and intermolecular hydrogen bonds in DNPH have been investigated by vibrational spectroscopic analysis.The mechanism of isothermal degradation of DNPH has been studied by differential scanning calorimetry (DSC).
2,4-Dinitrophenylhydrazine has been used as a reagent to detect the presence of aldehydes and ketones in protein carbonyls. It may be used as a colorimetric reagent in the quantitative estimation of prednisone.
Application:
2,4-Dinitrophenylhydrazine has been used as a reagent to detect the presence of aldehydes and ketones in protein carbonyls.It may be used as a colorimetric reagent in the quantitative estimation of prednisone.
| Sonrisas canónicas | C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])NN |
|---|---|
| IUPAC Name | (2,4-dinitrophenyl)hydrazine |
| InChIKey | HORQAOAYAYGIBM-UHFFFAOYSA-N |
| INCHI | 1S/C6H6N4O4/c7-8-5-2-1-4(9(11)12)3-6(5)10(13)14/h1-3,8H,7H2 |
| Isómeros SMILES | C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])NN |
| Número ONU | 3380 |
| Grupo de embalaje | I |
| Peso molecular | 198.14 |
| Beilstein | 615586 |
| Reaxy-Rn | 615586 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=615586&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Nitrobenzenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Nitrobenzenes |
| Alternative Parents | Phenylhydrazines Nitroaromatic compounds Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Organopnictogen compounds Organic zwitterions Organic oxides Hydrocarbon derivatives Hydrazines and derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Nitrobenzene - Nitroaromatic compound - Phenylhydrazine - C-nitro compound - Organic nitro compound - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Hydrazine derivative - Organic zwitterion - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as nitrobenzenes. These are compounds containing a nitrobenzene moiety, which consists of a benzene ring with a carbon bearing a nitro group. |
| External Descriptors | a small molecule |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Mar 09, 2026 | D112074 | |
| Certificate of Analysis | Mar 09, 2026 | D112074 | |
| Certificate of Analysis | Mar 09, 2026 | D112074 | |
| Certificate of Analysis | Mar 09, 2026 | D112074 | |
| Certificate of Analysis | Jan 04, 2026 | D112074 | |
| Certificate of Analysis | Mar 05, 2025 | D112074 | |
| Certificate of Analysis | Mar 05, 2025 | D112074 | |
| Certificate of Analysis | Mar 04, 2025 | D112074 | |
| Certificate of Analysis | Mar 04, 2025 | D112074 | |
| Certificate of Analysis | Mar 04, 2025 | D112074 | |
| Certificate of Analysis | Mar 04, 2025 | D112074 | |
| Certificate of Analysis | Jan 22, 2025 | D112074 | |
| Certificate of Analysis | Nov 19, 2024 | D112074 | |
| Certificate of Analysis | Nov 18, 2024 | D112074 | |
| Certificate of Analysis | Nov 18, 2024 | D112074 | |
| Certificate of Analysis | Nov 18, 2024 | D112074 | |
| Certificate of Analysis | Jul 30, 2024 | D112074 | |
| Certificate of Analysis | Jul 30, 2024 | D112074 | |
| Certificate of Analysis | Jul 30, 2024 | D112074 | |
| Certificate of Analysis | Jun 20, 2024 | D112074 | |
| Certificate of Analysis | Jun 20, 2024 | D112074 | |
| Certificate of Analysis | Apr 26, 2024 | D112074 | |
| Certificate of Analysis | Mar 26, 2024 | D112074 | |
| Certificate of Analysis | Mar 26, 2024 | D112074 | |
| Certificate of Analysis | Dec 12, 2023 | D112074 | |
| Certificate of Analysis | Dec 12, 2023 | D112074 | |
| Certificate of Analysis | Oct 20, 2023 | D112074 | |
| Certificate of Analysis | Oct 20, 2023 | D112074 | |
| Certificate of Analysis | Apr 19, 2023 | D112074 | |
| Certificate of Analysis | Apr 19, 2023 | D112074 | |
| Certificate of Analysis | Apr 19, 2023 | D112074 | |
| Certificate of Analysis | Nov 23, 2022 | D112074 | |
| Certificate of Analysis | Nov 23, 2022 | D112074 | |
| Certificate of Analysis | Nov 23, 2022 | D112074 | |
| Certificate of Analysis | Aug 16, 2022 | D112074 | |
| Certificate of Analysis | Aug 16, 2022 | D112074 | |
| Certificate of Analysis | Aug 16, 2022 | D112074 | |
| Certificate of Analysis | Aug 16, 2022 | D112074 | |
| Certificate of Analysis | Aug 16, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Jul 28, 2022 | D112074 | |
| Certificate of Analysis | Mar 19, 2022 | D112074 |
| Sensibilidad | Air and Light Sensitive |
|---|---|
| Punto de inflamación (°C) | 14°C |
| Punto de fusión (°C) | 196~199°C |
| Peso molecular | 198.140 g/mol |
| XLogP3 | 1.500 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 1 |
| Exact Mass | 198.039 Da |
| Monoisotopic Mass | 198.039 Da |
| Topological Polar Surface Area | 130.000 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 235.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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| 6. Kefan Ouyang, Hexiang Xie, Yufeng Wang, Fangjian Ning, Hua Xiong, Qiang Zhao. (2023) Color formation during the fibrillization of whey protein isolate: Maillard reaction and protein oxidation. FOOD HYDROCOLLOIDS, [PMID:] [10.1016/j.foodhyd.2023.108819] |
| 7. Jun-long Mao, Jing-jing Fu, Xue-er Qi, Yue-wen Chen, Bin Zhang. (2023) Effect of theaflavins on the quality of large yellow croaker (Larimichthys crocea) during refrigerated storage. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (12): (6033-6043). [PMID:37119403] [10.1002/jsfa.12671] |
| 8. Jinxin Li, Hao Zhang, Xijuan Yang, Ling Zhu, Gangcheng Wu, Hui Zhang. (2023) The fiber-bound polyphenols from highland barley with inhibitory effects against carbonyls during in vitro digestion of cookies and French fries. Food Bioscience, [PMID:] [10.1016/j.fbio.2023.102685] |
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| 12. HU Hao, LI Chengsheng, LYU Chunmao, MENG Xianjun, LI Bin, SHU Chi. (2023) Effect of protein oxidation on the structural characteristics of hazelnut protein isolate. Food Science and Technology, [PMID:] [10.1590/fst.103922] |
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| 14. Xiaomin Wang, Zengyuan Tian, Yu Xi, Yuqi Guo. (2022) Identification of endophytic fungi with ACC deaminase-producing isolated from halophyte Kosteletzkya Virginica. Plant Signaling & Behavior, [PMID:36463534] [10.1080/15592324.2022.2152224] |
| 15. Lin Xinghua, Hao Gugu, Xu Guobin, Sun Fuzhou, Xin Libo, Wu Shuming, Wang Zhongqing, You Jinsong, Huang Fangfang, Song Xuezhi. (2022) Structure Elucidation and Mechanistic Study of a New Dimer Impurity in Mirabegron Extended-Release Tablets. CHROMATOGRAPHIA, 86 (2): (185-197). [PMID:] [10.1007/s10337-022-04231-2] |
| 16. Yu Zhang, Dekun Cheng, Zhangtie Wang, Yiwen Guo, Ming Chang, Ruijie Liu. (2022) Protective Effect of Orbitides from Linseed (Linum usitatissimum L.) against Ultraviolet B-induced Photoaging in Zebrafish. PHOTOCHEMISTRY AND PHOTOBIOLOGY, [PMID:36484266] [10.1111/php.13758] |
| 17. Lin Shan Shi, Xue Yan Yang, Tian Gong, Ching Yuan Hu, Ye Hua Shen, Yong Hong Meng. (2022) Ultrasonic treatment improves physical and oxidative stabilities of walnut protein isolate-based emulsion by changing protein structure. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2022.114269] |
| 18. Hao Zhang, Antonio Dario Troise, Shangde Sun, Vincenzo Fogliano. (2022) The water insoluble fraction from red cabbage and black currant pomace reduces the formation of acrylamide, 5-hydroxymethylfurfural and reactive aldehydes in fried potato-based crisps. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2022.114238] |
| 19. Heng Zhao, Xiaolin Ma, Mingjie Lu, Fengting He, Feifei Lin, Yang Zhang, Jinqiang Zhang, Pei Dong, Chaocheng Zhao, Hongqi Sun. (2022) Melamine foam derived nitrogen and boron co-doped metal-free electrode for enhanced electro-Fenton degradation of metronidazole. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2022.140593] |
| 20. Yang Chen, Mengying Yao, Tianyi Yang, Yajing Fang, Dong Xiang, Weimin Zhang. (2022) Changes in structure and emulsifying properties of coconut globulin after the atmospheric pressure cold plasma treatment. FOOD HYDROCOLLOIDS, [PMID:] [10.1016/j.foodhyd.2022.108289] |
| 21. Die Wang, Luminita Marin, Xinjian Cheng. (2022) Chitosan-bodipy macromolecular fluorescent probes prepared by click reactions for highly sensitive and selective recognition of 2,4-dinitrophenylhydrazine. NEW JOURNAL OF CHEMISTRY, 46 (43): (20699-20710). [PMID:] [10.1039/D2NJ03923K] |
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| 25. Jinxing Zhang, Jie Sun, Hongying Zhao, Guohua Zhao. (2022) Single-Atom Copper Promotes Efficient Generation of Hydroxyl Radicals under Alkaline Circumstances in a Photoelectrochemical Oxygen Reduction Process. ACS ES&T Engineering, [PMID:] [10.1021/acsestengg.2c00119] |
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| 40. Weilu Yang, Minghua Zhou, Lei Mai, Huase Ou, Nihal Oturan, Mehmet A. Oturan, Eddy Y. Zeng. (2021) Generation of hydroxyl radicals by metal-free bifunctional electrocatalysts for enhanced organics removal. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:34118668] [10.1016/j.scitotenv.2021.148107] |
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