2(5H)-Furanone - Moligand™, ≥98% , CAS No.497-23-4

CAS: 497-23-4 Cat. No.: F107943 Peso molecular: 84.07 Beilstein Registry Number: 383585 Número EC: 207-839-3
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
EN300-80159 | g-Crotonolactone | laquo deltaRaquo ,alpha,beta-butenolide | 4-Hydroxy-2-butenoic acid .gamma.-lactone | FT-0608698 | 2,5-Dihydrofuranone | 2-Butenoic acid-laquo gammaRaquo -lactone | 4-Hydroxy-2-butenoic acid lactone | gamma-Hydroxycrotonic
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1g
F107943-1g
10
9,90US$
5g
F107943-5g
7
12,90US$
25g
F107943-25g
3

30,90US$

33,90US$
Guardar 3,00 US$ (8.85%)
100g
F107943-100g
1

111,90US$

119,90US$
Guardar 8,00 US$ (6.67%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (γ-crotonolactone) to pyrrolidine.The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains.

Specifications

Sinónimos
EN300-80159 | g-Crotonolactone | laquo deltaRaquo , alpha, beta-butenolide | 4-Hydroxy-2-butenoic acid .gamma.-lactone | FT-0608698 | 2, 5-Dihydrofuranone | 2-Butenoic acid-laquo gammaRaquo -lactone | 4-Hydroxy-2-butenoic acid lactone | gamma-Hydroxycrotonic
Especificaciones y pureza
Moligand™, ≥98%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Protected from light, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Pureza
≥98%
Nombres e identificadores
Pubchem Sid488181119
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181119
Sonrisas canónicasC1C=CC(=O)O1
IUPAC Name2H-furan-5-one
InChIKeyVIHAEDVKXSOUAT-UHFFFAOYSA-N
INCHI1S/C4H4O2/c5-4-2-1-3-6-4/h1-2H,3H2
Isómeros SMILES C1C=CC(=O)O1
WGK Alemania 3
RTECS LU3453000
Peso molecular 84.07
Beilstein 383585
Reaxy-Rn 383585
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=383585&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseDihydrofurans
SubclassFuranones
Intermediate Tree Nodes Not available
Direct ParentButenolides
Alternative Parents Enoate esters  Lactones  Oxacyclic compounds  Monocarboxylic acids and derivatives  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAliphatic heteromonocyclic compounds
Substituents 2-furanone - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Lactone - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
External Descriptors butenolide
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA1 Tclin Carbonic anhydrase I (13240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA9 Tclin Carbonic anhydrase IX (8255 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Gamma-hydroxybutyrate receptor (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plutella xylostella (1838 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ascia monuste (100 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

27 results found

Lot NumberCertificate TypeFechaArticulo
F2415139Certificate of AnalysisMar 18, 2026 F107943
F2421262Certificate of AnalysisMar 17, 2026 F107943
J2516586Certificate of AnalysisSep 27, 2025 F107943
J2516588Certificate of AnalysisSep 27, 2025 F107943
J2516585Certificate of AnalysisSep 27, 2025 F107943
J2516587Certificate of AnalysisSep 27, 2025 F107943
C2630127Certificate of AnalysisSep 27, 2025 F107943
D2622089Certificate of AnalysisSep 27, 2025 F107943
E23061018Certificate of AnalysisFeb 07, 2025 F107943
E23061032Certificate of AnalysisFeb 07, 2025 F107943
E23061030Certificate of AnalysisFeb 07, 2025 F107943
E23061027Certificate of AnalysisFeb 07, 2025 F107943
E23061015Certificate of AnalysisFeb 07, 2025 F107943
E23061014Certificate of AnalysisFeb 07, 2025 F107943
E23061013Certificate of AnalysisFeb 07, 2025 F107943
E23061010Certificate of AnalysisFeb 07, 2025 F107943
F2415140Certificate of AnalysisMar 30, 2024 F107943
F2421260Certificate of AnalysisMar 29, 2024 F107943
F2421261Certificate of AnalysisMar 29, 2024 F107943
A1826073Certificate of AnalysisJun 05, 2023 F107943
C2307229Certificate of AnalysisMar 11, 2023 F107943
B2318491Certificate of AnalysisFeb 23, 2023 F107943
B2310622Certificate of AnalysisFeb 16, 2023 F107943
L2205656Certificate of AnalysisDec 10, 2022 F107943
A2105076Certificate of AnalysisOct 19, 2022 F107943
A2105075Certificate of AnalysisOct 19, 2022 F107943
I2209066Certificate of AnalysisSep 16, 2022 F107943

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Propiedades químicas y físicas
SolubilidadImmiscible with water.
SensibilidadHeat,Light & Air sensitive.
Índice de refracción1.469
Punto de inflamación (°F)213.8 °F
Punto de inflamación (°C)101 °C
Punto de ebullición (°C)214°C
Punto de fusión (°C)4-5°C
Peso molecular84.070 g/mol
XLogP3-0.600
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass84.0211 Da
Monoisotopic Mass84.0211 Da
Topological Polar Surface Area26.300 Ų
Heavy Atom Count6
Formal Charge0
Complexity93.700
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Xinjing Li, Yishun Yao, Xue Xia, Foxin Zhang, Jingyang Yu, Heping Cui, Yunwei Niu, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho.  (2023)  Maillard Reaction Process and Characteristic Volatile Compounds Formed During Secondary Thermal Degradation Monitored via the Change of Fluorescent Compounds in the Reaction of Xylose–Corn Protein Hydrolysate.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38115213] [10.1021/acs.jafc.3c08082]
2. Xinxin Li, Linchuan Cong, Yupeng Wu, Nan Lin, Fangbing Liu, Deyuan Xin, Fuyu Han, Jin Yang, Weitong Chen, Haibo Lin.  (2023)  Strategies for controlling gas evolution reactions to boost the divergent paired electrochemical upgrading of furfural in acidic environment.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.144093]
3. Linhui Feng, Heping Cui, Pusen Chen, Khizar Hayat, Xiaoming Zhang, Chi-Tang Ho.  (2022)  Promoted Formation of Pyrazines and Sulfur-Containing Volatile Compounds through Interaction of Extra-Added Glutathione or Its Constituent Amino Acids and Secondary Products of Thermally Degraded N-(1-Deoxy-d-ribulos-1-yl)-Glutathione.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:35838405] [10.1021/acs.jafc.2c02949]
4. Liu Mengfan, Yao Jingjing, Zhang Chengliang, Hao Runqin, Zhang Zhongguo, Cao Wenbo.  (2022)  Quantitative analysis of multi-components by single-marker: An effective method for the chemical characterization of wood vinegar.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2022.114862]
5. Tao Yang, Wenzhi Li, Ajibola T. Ogunbiyi.  (2021)  The effect of Br- and alkali in enhancing the oxidation of furfural to maleic acid with hydrogen peroxide.  Molecular Catalysis,      [PMID:] [10.1016/j.mcat.2021.111488]
6. Lin Zhu, Tao Chen, Lan Xu, Zhenchao Zhou, Wanqiu Feng, Yang Liu, Hong Chen.  (2019)  Effect and mechanism of quorum sensing on horizontal transfer of multidrug plasmid RP4 in BAC biofilm.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:31493577] [10.1016/j.scitotenv.2019.134236]
7. Xiaomin Xiang, Bin Zhang, Guoqiang Ding, Jinglei Cui, Hongyan Zheng, Yulei Zhu.  (2016)  The effect of Mg(OH)2 on furfural oxidation with H2O2.  CATALYSIS COMMUNICATIONS,      [PMID:] [10.1016/j.catcom.2016.08.013]
8. Liu Shengqin, Jin Yangxin, Huang Shuquan, Zhu Qi, Shao Shan, Lam Jason Chun-Ho.  (2024)  One-pot redox cascade paired electrosynthesis of gamma-butyrolactone from furoic acid.  Nature Communications,  15  (1): (1-11).  [PMID:38326323] [10.1038/s41467-024-45278-z]
9. Xiaowei Liu, Chuang Huang, Hongxia Yu, Yaning Yang, Lulu Ma, Bin Zhao, Tianyang Zhong, Lilan Zhang, Weihua Peng, Wenwen Gong, Yan Ding.  (2024)  Quorum sensing regulating the heterogeneous transformation of antibiotic resistance genes in microplastic biofilms.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2024.113698]
10. Qi Zhou, Xiao Jia, Ying-Zheng Yao, Bei Wang, Chang-Qing Wei, Min Zhang, Fenghong Huang.  (2019)  Characterization of the Aroma-Active Compounds in Commercial Fragrant Rapeseed Oils via Monolithic Material Sorptive Extraction.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:31529950] [10.1021/acs.jafc.9b05691]
11. Shengqin Liu, Yangxin Jin, Qi Zhu, Xiaodan Xu, Shan Shao, Kartick Chandra MAJHI, Qingguo Le, Jieming Huang, Jian Zhang, Zupeng Chen, Jason Chun-Ho Lam.  (2025)  Membrane-Free One-pot Cascaded Electrocatalytic Redox of Furfural into Gamma-Butyrolactone.  GREEN CHEMISTRY,      [PMID:] [10.1039/D5GC03829D]
12. Junyi Wang, Jing Wang, Yan Gao, Ning Zhang, Baoguo Sun, Fuping Zheng, Haitao Chen.  (2025)  Decoding Qingke's aroma compounds: Flavor contributions, interactions and barley contrast.  FOOD CHEMISTRY,      [PMID:41109048] [10.1016/j.foodchem.2025.146612]
13. Shuge Yuan, Yahui Liu, Jinglin Yu, Ping Yang, Wei Yong, Zongxu Zhao, Tianyang Guo, Huanlu Song.  (2025)  Molecular sensory insights into odor activity and formation pathway of volatile compounds across roasting degrees in coffee beans.  JOURNAL OF FOOD COMPOSITION AND ANALYSIS,      [PMID:] [10.1016/j.jfca.2025.107712]
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