GRADE & PURITY ≥98%

Synonyms

4,6-Dimethyl-2-aminopyridine | 7NVZ9DW9Q5 | STL557611 | W-105678 | 2-amino-4,6-dimethyl pyridine | 2-amino-4.6-dimethylpyridine | 2-Pyridinamine 4,6-dimethyl- | BRN 0002048 | AM20070146 | BBL103801 | Z1192367241 | AKOS005145684 | 2-Pyridinamine, 4,6-dimet

Storage

Room temperature

Shipped In

Normal

Specifications

Sinónimos

4, 6-Dimethyl-2-aminopyridine | 7NVZ9DW9Q5 | STL557611 | W-105678 | 2-amino-4, 6-dimethyl pyridine | 2-amino-4.6-dimethylpyridine | 2-Pyridinamine 4, 6-dimethyl- | BRN 0002048 | AM20070146 | BBL103801 | Z1192367241 | AKOS005145684 | 2-Pyridinamine, 4, 6-dimet

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504753040
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504753040
• Sonrisas canónicas: CC1=CC(=NC(=C1)N)C
• IUPAC Name: 4,6-dimethylpyridin-2-amine
• InChIKey: BRBUBVKGJRPRRD-UHFFFAOYSA-N
• INCHI: 1S/C7H10N2/c1-5-3-6(2)9-7(8)4-5/h3-4H,1-2H3,(H2,8,9)
• Isómeros SMILES: CC1=CC(=NC(=C1)N)C
• WGK Alemania: 3
• RTECS: US1818000
• Peso molecular: 122.17
• Reaxy-Rn: 2048
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2048&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Pyridines and derivatives
      • Subclass Aminopyridines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Pyridines and derivatives
• Subclass: Aminopyridines and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Aminopyridines and derivatives
• Alternative Parents: Methylpyridines Imidolactams Heteroaromatic compounds Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Methylpyridine - Aminopyridine - Imidolactam - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as aminopyridines and derivatives. These are organic heterocyclic compounds containing an amino group attached to a pyridine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

NOS2 Tchem Nitric oxide synthase, inducible (3 Activities)

Discover Target: NOS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS1 Tchem Nitric oxide synthase, brain (2 Activities)

Discover Target: NOS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS3 Tchem Nitric oxide synthase, endothelial (3 Activities)

Discover Target: NOS3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)

Discover Target: NOS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NOS3 Tchem Nitric-oxide synthase, endothelial (1452 Activities)

Discover Target: NOS3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NOS1 Tchem Nitric oxide sythases; iNOS & nNOS (685 Activities)

Discover Target: NOS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIK3R1 Tchem PI3-kinase p110-alpha/p85-alpha (2589 Activities)

Discover Target: PIK3R1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

PIK3CA PI3-kinase p110-alpha subunit (51 Activities)

Discover Target: PIK3CA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nos2 Nitric oxide synthase, inducible (3573 Activities)

Discover Target: Nos2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Punto de ebullición (°C): 231°C
• Punto de fusión (°C): 67°C
• Peso molecular: 122.170 g/mol
• XLogP3: 1.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 122.084 Da
• Monoisotopic Mass: 122.084 Da
• Topological Polar Surface Area: 38.900 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 92.900
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Li-Jing Zhu, Li-Ping Zhu, Pei-Bin Zhang, Bao-Ku Zhu, You-Yi Xu.  (2016)  Surface zwitterionicalization of poly(vinylidene fluoride) membranes from the entrapped reactive core–shell silica nanoparticles.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:26835581] [10.1016/j.jcis.2016.01.043]

2. Li-Jing Zhu, Li-Ping Zhu, Yi-Fan Zhao, Bao-Ku Zhu, You-Yi Xu.  (2014)  Anti-fouling and anti-bacterial polyethersulfone membranes quaternized from the additive of poly(2-dimethylamino ethyl methacrylate) grafted SiO2 nanoparticles.  Journal of Materials Chemistry A,  2  (37): (15566-15574).  [PMID:] [10.1039/C4TA03199G]

3. Li-Jing Zhu, Li-Ping Zhu, Jin-Hong Jiang, Zhuan Yi, Yi-Fan Zhao, Bao-Ku Zhu, You-Yi Xu.  (2013)  Hydrophilic and anti-fouling polyethersulfone ultrafiltration membranes with poly(2-hydroxyethyl methacrylate) grafted silica nanoparticles as additive.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2013.09.053]

4. Zhuan Yi, Liping Zhu, Liang Cheng, Baoku Zhu, Youyi Xu.  (2011)  A readily modified polyethersulfone with amino-substituted groups: Its amphiphilic copolymer synthesis and membrane application.  POLYMER,      [PMID:] [10.1016/j.polymer.2011.11.053]