2-Amino-5-methylthiazole - ≥98% , CAS No.7305-71-7

CAS: 7305-71-7 Cat. No.: A102155 Peso molecular: 114.17 Beilstein Registry Number: 109603 Número EC: 423-800-5

GRADE & PURITY ≥98%

Synonyms

AM20100697 | A56079 | AKOS000120781 | 2-amino-5-methyl-1,3-thiazole | STR04839 | 7RAB78AF2P | 2-amino-5-methyl thiazole | BDBM50271509 | FT-0611180 | 2-Thiazolamine, 5-methyl- | J-507967 | SCHEMBL160815 | (5-Methylthiazol-2-yl)amine | 2-Amino-5-methylthia

Storage

Store at 2-8°C

Shipped In

Wet ice

Descripción general

Product Description
2-Amino-5-methylthiazole is a heterocyclic building block. It is one of the major alkaline metabolite of tenoxicam (TX) and meloxicam (MX).
Product Application
2-Amino-5-methylthiazole may be used in the preparation of acrylamide monomer, 5-methyl-2-thiozyl methacrylamide (MTMAAm). 2-Amino-5-methylthiazole may be used in the preparation of mixed-ligand dien-Cu(II) complexes (dien=diethylenetriamine). It may be used in the preparation of a new series of Schiff mono/dibase coordination compounds, having potential anticancer and antibacterial activities.

Specifications

Sinónimos

AM20100697 | A56079 | AKOS000120781 | 2-amino-5-methyl-1, 3-thiazole | STR04839 | 7RAB78AF2P | 2-amino-5-methyl thiazole | BDBM50271509 | FT-0611180 | 2-Thiazolamine, 5-methyl- | J-507967 | SCHEMBL160815 | (5-Methylthiazol-2-yl)amine | 2-Amino-5-methylthia

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504758564
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504758564
• Sonrisas canónicas: CC1=CN=C(S1)N
• IUPAC Name: 5-methyl-1,3-thiazol-2-amine
• InChIKey: GUABFMPMKJGSBQ-UHFFFAOYSA-N
• INCHI: 1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6)
• Isómeros SMILES: CC1=CN=C(S1)N
• WGK Alemania: 3
• Número ONU: 3077
• Peso molecular: 114.17
• Beilstein: 109603
• Reaxy-Rn: 109603
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=109603&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Azoles
      • Subclass Thiazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Azoles
• Subclass: Thiazoles
• Intermediate Tree Nodes: Not available
• Direct Parent: 2,5-disubstituted thiazoles
• Alternative Parents: 2-amino-1,3-thiazoles Heteroaromatic compounds Azacyclic compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: 2,5-disubstituted 1,3-thiazole - 1,3-thiazol-2-amine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 2,5-disubstituted thiazoles. These are compounds containing a thiazole ring substituted at positions 2 and 5 only.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)

Discover Target: NOS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

ddlB D-alanylalanine synthetase (66 Activities)

Discover Target: ddlB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase (389 Activities)

Discover Target: murA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in Methanol
• Sensibilidad: heat sensitive
• Punto de fusión (°C): 93-98°C
• Peso molecular: 114.170 g/mol
• XLogP3: 1.000
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 114.025 Da
• Monoisotopic Mass: 114.025 Da
• Topological Polar Surface Area: 67.200 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 66.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1