2-Aminoethyl methacrylate hydrochloride - ≥90% , CAS No.2420-94-2

CAS: 2420-94-2 Cat. No.: A168938 Peso molecular: 165.62 Número EC: 219-343-4

GRADE & PURITY ≥90%

Synonyms

2-Aminoethylmethacrylatehydrochloride | 2-aminoethyl 2-methylprop-2-enoate hydrochloride | 2-aminoethyl 2-methylacrylate hydrochloride | MFCD00078260 | 2-Methyl-2-propenoic Acid 2-Aminoethyl Ester Hydrochloride | Methacrylic Acid 2-Aminoethyl Ester Hydroc

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Descripción general

Aminoethyl methacrylate hydrochloride (AMA) is an amine based methacrylic monomer used in the production of polymers and copolymers that are utilized in a wide range of applications, including coatings, adhesives, and medical devices. It is a highly reactive monomer due to the presence of the methacrylate group, which enables it to undergo both free radical polymerization and other polymerization reactions. Due to its biocompatibility and low toxicity, it is widely used in biomedical research and as a crosslinking agent for hydrogels and other biomaterials. It is used in the synthesis of poly (2-aminoethylmethacrylate), a biocompatible cationic polymer widely used in the biomedical field.

Application：

2-Aminoethylmethacrylate hydrochloride(AMA) can be used as a precursor to synthesize: Homo and copolymer brushes of AMA, which can be used to tune the electrochemical properties of silicon wafers. Poly(3-hydroxybutyrate) based polyurethane/urea composite scaffolds for tissue engineering applications. Antimicrobial bacterial cellulose/poly (AMA) nanocomposites. Polymer incorporation imparts mechanical properties and antimicrobial activity to bacterial cellulose membranes.
It can also be used for the efficient functionalization of hyaluronic acid via triazine-mediated amidation.

Specifications

Sinónimos

2-Aminoethylmethacrylatehydrochloride | 2-aminoethyl 2-methylprop-2-enoate hydrochloride | 2-aminoethyl 2-methylacrylate hydrochloride | MFCD00078260 | 2-Methyl-2-propenoic Acid 2-Aminoethyl Ester Hydrochloride | Methacrylic Acid 2-Aminoethyl Ester Hydroc

Especificaciones y pureza

≥90%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥90%

Nombres e identificadores

• Pubchem Sid: 488185114
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488185114
• Sonrisas canónicas: CC(=C)C(=O)OCCN.Cl
• IUPAC Name: 2-aminoethyl 2-methylprop-2-enoate;hydrochloride
• InChIKey: XSHISXQEKIKSGC-UHFFFAOYSA-N
• INCHI: 1S/C6H11NO2.ClH/c1-5(2)6(8)9-4-3-7;/h1,3-4,7H2,2H3;1H
• Isómeros SMILES: CC(=C)C(=O)OCCN.Cl
• WGK Alemania: 1
• CAS alternativo: 7659-36-1
• Peso molecular: 165.62
• Reaxy-Rn: 6781593
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6781593&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Carboxylic acid derivatives
        • Level5 Carboxylic acid esters
          • Level6 Alpha,beta-unsaturated carboxylic esters
            • Level7 Enoate esters

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Carboxylic acid derivatives
• Intermediate Tree Nodes: Carboxylic acid esters - Alpha,beta-unsaturated carboxylic esters
• Direct Parent: Enoate esters
• Alternative Parents: Amino acids and derivatives Monocarboxylic acids and derivatives Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Enoate ester - Amino acid or derivatives - Monocarboxylic acid or derivatives - Amine - Organic oxide - Hydrocarbon derivative - Hydrochloride - Organopnictogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Primary aliphatic amine - Carbonyl group - Organic nitrogen compound - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as enoate esters. These are an alpha,beta-unsaturated carboxylic ester of general formula R1C(R2)=C(R3)C(=O)OR4 (R4= organyl compound) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Solubility in water: Completely soluble; Very soluble in Acetone
• Sensibilidad: Air Sensitive,Hygroscopic,Heat Sensitive
• Punto de fusión (°C): 119 °C
• Peso molecular: 165.620 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 165.056 Da
• Monoisotopic Mass: 165.056 Da
• Topological Polar Surface Area: 52.300 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 120.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Haifeng Ni, Sunxiang Qian, Jie Lu, Jie Feng, Xiao-zhou Mou, Jing Zhang.  (2023)  Natural Polysaccharide Delivery Platforms with Multiscale Structure Used for Cancer Chemoimmunotherapy.  MOLECULAR PHARMACEUTICS,      [PMID:37752866] [10.1021/acs.molpharmaceut.3c00633]

2. Hao Ye, Tian-Hao Li, Yu-Qi Huang, Jia-Min Jin, Jin-Yan Fei, Ming-Bang Wu, Juming Yao.  (2022)  Amyloid-like coatings decorated electrodes boost the uranium electro-adsorption from seawater.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.138615]

3. Lingling Pan, Dawei Jiang, Luqi Pan, Zhizhen Meng, Yangyang Zhuang, Yueyue Huang, Fanrong Ye, Changcan Shi, Jie Chen, Jingye Pan.  (2022)  ICAM-1-targeted and antibacterial peptide modified polymeric nanoparticles for specific combating sepsis.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2022.111007]

4. Jiajun Qin, Ming Li, Ming Yuan, Xinglei Shi, Jiliang Song, Yiyan He, Hongli Mao, Deling Kong, Zhongwei Gu.  (2022)  Gallium(III)-Mediated Dual-Cross-Linked Alginate Hydrogels with Antibacterial Properties for Promoting Infected Wound Healing.  ACS Applied Materials & Interfaces,      [PMID:35533377] [10.1021/acsami.2c02497]

5. Qian Wang, Yunbo Feng, Min He, Weifeng Zhao, Li Qiu, Changsheng Zhao.  (2020)  A Hierarchical Janus Nanofibrous Membrane Combining Direct Osteogenesis and Osteoimmunomodulatory Functions for Advanced Bone Regeneration.  ADVANCED FUNCTIONAL MATERIALS,  31  (8): (2008906).  [PMID:] [10.1002/adfm.202008906]

6. Jingqi Ji, Jianqing Zhao, Yangchuan Ke.  (2019)  Synthesis and characterization of poly(AM-SSS-AMPS)/ O-MMT nanocomposite microspheres with tailored nanomechanical properties.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2019.124022]

7. Xiaoran Deng, Yunlu Dai, Jianhua Liu, Ying Zhou, Ping'an Ma, Ziyong Cheng, Yinyin Chen, Kerong Deng, Xuejiao Li, Zhiyao Hou, Chunxia Li, Jun Lin.  (2015)  Multifunctional hollow CaF2:Yb3+/Er3+/Mn2+-poly(2-Aminoethyl methacrylate) microspheres for Pt(IV) pro-drug delivery and tri-modal imaging.  BIOMATERIALS,      [PMID:25736505] [10.1016/j.biomaterials.2015.01.040]

8. Yang Wang, Jinshan Nie, Baisong Chang, Yangfei Sun, Wuli Yang.  (2013)  Poly(vinylcaprolactam)-Based Biodegradable Multiresponsive Microgels for Drug Delivery.  BIOMACROMOLECULES,      [PMID:23909593] [10.1021/bm401131w]

9. Xiao Song, Chuanjiang Zhou, Shengjie Liu, Zhaoqiang Wu, Hong Chen.  (2024)  A novel poly(2-hydroxyethyl acrylamide) copolymer for the fabrication of transparent antifogging coatings on polycarbonate substrates.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2024.134297]

10. Song Xiao, Zhou Chuanjiang, Yang Sijia, Liu Shengjie, Wu Zhaoqiang, Chen Hong.  (2025)  A transparent, abrasion-resistant anti-fog coating on polycarbonate substrates.  Journal of Coatings Technology and Research,      [PMID:] [10.1007/s11998-024-01056-6]

11. Changchun Liu, Jiaqi Liu, Minmin Wu, Haifeng Ni, Jie Feng, Liping Zhao, Jing Zhang.  (2024)  Cryogel wound dressings based on natural polysaccharides perfectly adhere to irregular wounds for rapid haemostasis and easy disassembly.  WOUND REPAIR AND REGENERATION,  32  (4): (393-406).  [PMID:38494792] [10.1111/wrr.13173]

12. Wei JunJie, Shen Yong, Ouyang GangFeng.  (2025)  Determination of circulating tumor cells by surface-enhanced Raman scattering based on molecularly imprinted polymers doped with silver nanoparticles.  ANALYTICAL SCIENCES,      [PMID:39998807] [10.1007/s44211-025-00719-7]

13. Junpeng Xu, Peng Dai, Chen Zhang, Na Dong, Caiyan Li, Chonghui Tang, Zhihao Jin, Shih-Ho Lin, Luyang Ye, Tianmiao Sun, Yukai Jin, Fenzan Wu, Lihua Luo, Ping Wu, Shengcun Li, Xiaokun Li, Shan-hui Hsu, Dawei Jiang, Zhouguang Wang.  (2024)  Injectable Hierarchical Bioactive Hydrogels with Fibroblast Growth Factor 21/Edaravone/Caffeic Acid Asynchronous Delivery for Treating Parkinson's Disease.  Advanced Science,      [PMID:39630931] [10.1002/advs.202412020]

14. Zhihao Wang, Qiuli Cheng, Xingda Jiang, Xinyang Chu, Bingcan Li, Leitao Zhang, Wenlan Wu, Junbo Li, Ravin Narain.  (2024)  pH/Hypoxia dual-stimuli responsive COF nanocarriers with reversible charge conversions for the accurate tumor-targeting and enhanced anticancer drug delivery.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2024.135277]

15. Wan Peng, Youjin Lai, Jin Fan, Chuanchao Dai, Jian Shen, Pingsheng Liu.  (2024)  Simple component self-gelling powders as multifunctional tissue adhesives for sutureless wound healing.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.153514]

16. Liu Hua, Chen Zhijie, Lin Qiaowen, Chen Yi, Hong Liwen, Zhong Jie, Cai Zhengwei, Wang Zhengting, Cui Wenguo.  (2025)  A multicellular self-organized probiotic platform for oral delivery enhances intestinal colonization.  Nature Communications,  16  (1): (1-16).  [PMID:40750778] [10.1038/s41467-025-62349-x]

17. Xin Zhang, Zhengwei Xu, Hong Zhang, Zhenchun Li, Bo Ren, Bo Wang, Xiaodong Yang, Junqiu Liu.  (2025)  An integrated Janus antibacterial hydrogel with rapid photoresponsive adhesive/tough anti-adhesive bi-layer for enhanced wound healing and suppression of postoperative tissue adhesion.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40886992] [10.1016/j.ijbiomac.2025.147209]

18. Ye Han Yan, Muhammad Atif, Ren Yong Liu, Hai Kun Zhu, Li Juan Chen.  (2020)  Design of comb-like poly(2-methyl-2-oxazoline) and its rapid co-deposition with dopamine for the study of antifouling properties.  JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION,      [PMID:31791188] [10.1080/09205063.2019.1697169]

19. Long Zhang, Manyu Xue, Qi Xin, Jie Tang, Yin Liu, Zhengyang Bian, Xiaoping Zheng.  (2025)  Cellular uptake of polystyrene nanoplastics with surface Functionalization: An AIE-based quantitative approach.  ANALYTICA CHIMICA ACTA,      [PMID:40447404] [10.1016/j.aca.2025.344184]

20. Yishi Cheng, Peng Ni, Jinwei Su, Xiaofei Luo, Runlan Chen, Xianmou Fan, Yan Fang, Qinhui Chen, Yunxiang Weng, Haiqing Liu.  (2025)  Antibacterial, Tissue-Selective and Robust Wet Adhesive Hydrogel Enhanced With Modified Polyethyleneimine.  JOURNAL OF APPLIED POLYMER SCIENCE,      [PMID:] [10.1002/app.70132]

21. Cheng Zheng, Bangquan Wei, Lepeng Chen, Xueyu Huang, Yunbing Wang.  (2026)  Bioinspired hydrogel-engineered bioprosthetic valve via metal-polyphenol-polysaccharide coordinated assembly for thromboresistance, accelerated endothelialization, and immunoregulation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2026.174500]

22. Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang.  (2026)  DOTA-grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance-reversal Agents (MRRAs) Combating Against New Delhi Metallo-β-lactamase (NDM)-producing Bacteria.  Advanced Science,      [PMID:] [10.1002/advs.202519056]