2-Aminopyridine(2-AP) - ≥99% , CAS No.504-29-0

CAS: 504-29-0 Cat. No.: A105222 Peso molecular: 94.11 Beilstein Registry Number: 105785 Número EC: 207-988-4
Disponible para pedir
GRADE & PURITY ≥99%
Synonyms
2-AP | DTXSID0024505 | NCGC00258434-01 | aminopyridin | MEPYRAMINE MALEATE IMPURITY C [EP IMPURITY] | o-Aminopyridine [UN2671] [Poison] | EC 207-988-4 | Z104472278 | iminopyridine | Pyridin-2-amine (2-Pyridylamine) | DTXCID404505 | pyridineamine | pyridi
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice,FedEx DG Service
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
25g
A105222-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
9,90US$
100g
A105222-100g
2

14,90US$

19,90US$
Guardar 5,00 US$ (25.13%)
250g
A105222-250g
2
29,90US$
500g
A105222-500g
1
49,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice,FedEx DG Service Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

2-Aminopyridine is a basic building block of several heterocyclic compounds and Schiff bases.
A compound has been shown to reversibly block voltage-dependent potassium channels.2-Aminopyridine (2AP) is a derivatizing agent which can be used as a fluorescent label for oligosaccharide detection, chromatographic separation, fluorometric or mass spectrometric analysis. 2AP and its derivatives are good candidates for antimicrobial, anticorrosion and molecular sensing applications.

Specifications

Sinónimos
2-AP | DTXSID0024505 | NCGC00258434-01 | aminopyridin | MEPYRAMINE MALEATE IMPURITY C [EP IMPURITY] | o-Aminopyridine [UN2671] [Poison] | EC 207-988-4 | Z104472278 | iminopyridine | Pyridin-2-amine (2-Pyridylamine) | DTXCID404505 | pyridineamine | pyridi
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
2-Aminopyridine is a compound has been shown to reversibly block voltage-dependent potassium channels, and is also a common impurity from the synthesis of compounds found in hair dye.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Protected from light, Argon charged
Enviado en
Wet ice, FedEx DG Service
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥99%
Nombres e identificadores
Sonrisas canónicasC1=CC=NC(=C1)N
IUPAC Namepyridin-2-amine
InChIKeyICSNLGPSRYBMBD-UHFFFAOYSA-N
INCHI1S/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7)
Isómeros SMILES C1=CC=NC(=C1)N
WGK Alemania 3
RTECS US1575000
Número ONU 2671
Grupo de embalaje II
Peso molecular 94.11
Beilstein 105785
Reaxy-Rn 105785
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=105785&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasePyridines and derivatives
SubclassAminopyridines and derivatives
Intermediate Tree Nodes Not available
Direct ParentAminopyridines and derivatives
Alternative Parents Imidolactams  Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Aminopyridine - Imidolactam - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as aminopyridines and derivatives. These are organic heterocyclic compounds containing an amino group attached to a pyridine ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HSP90AA1 Tchem Heat shock protein HSP 90-alpha (4115 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NOS3 Tchem Nitric-oxide synthase, endothelial (1452 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCF1 Tbio Neutrophil cytosol factor 1 (245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PI4K2A Tbio Phosphatidylinositol 4-kinase, PI4K (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Tec Tyrosine-protein kinase TEC (25 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Human immunodeficiency virus 1 (70413 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
botA Botulinum neurotoxin type A (1303 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chrna3 Neuronal acetylcholine receptor (756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
gyrB DNA gyrase (2092 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate TypeFechaArticulo
E2625024Certificate of AnalysisJun 04, 2026 A105222
K2108518Certificate of AnalysisAug 12, 2025 A105222
K2108515Certificate of AnalysisAug 12, 2025 A105222
H2501113Certificate of AnalysisJul 21, 2025 A105222
H2501114Certificate of AnalysisJul 21, 2025 A105222
H2501115Certificate of AnalysisJul 21, 2025 A105222
H2501186Certificate of AnalysisJul 21, 2025 A105222
J2423363Certificate of AnalysisOct 12, 2024 A105222
J2423348Certificate of AnalysisOct 12, 2024 A105222
J2423343Certificate of AnalysisOct 12, 2024 A105222
J2423342Certificate of AnalysisOct 12, 2024 A105222
J2423335Certificate of AnalysisOct 12, 2024 A105222
J2423334Certificate of AnalysisOct 12, 2024 A105222
L2508156Certificate of AnalysisJul 13, 2024 A105222
L2508155Certificate of AnalysisJul 13, 2024 A105222
K1815013Certificate of AnalysisSep 16, 2022 A105222
J2210069Certificate of AnalysisJun 04, 2022 A105222
J2210068Certificate of AnalysisJun 04, 2022 A105222
J2210067Certificate of AnalysisJun 04, 2022 A105222
J2210066Certificate of AnalysisJun 04, 2022 A105222
J2210051Certificate of AnalysisJun 04, 2022 A105222
I2301213Certificate of AnalysisJun 04, 2022 A105222
H2301213Certificate of AnalysisJun 04, 2022 A105222
A2417114Certificate of AnalysisJun 04, 2022 A105222
G2204050Certificate of AnalysisOct 25, 2021 A105222

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Propiedades químicas y físicas
SolubilidadSlightly soluble in water(8g/100 mL at 19°C);Soluble in alcohol, benzene, Acetone, ether
SensibilidadHeat,Light & Moisture Sensitive.
Punto de inflamación (°F)197.6 °F
Punto de inflamación (°C)92℃
Punto de ebullición (°C)210.6°C
Punto de fusión (°C)61°C
Peso molecular94.110 g/mol
XLogP30.500
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass94.0531 Da
Monoisotopic Mass94.0531 Da
Topological Polar Surface Area38.900 Ų
Heavy Atom Count7
Formal Charge0
Complexity54.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Wei Sun, Guqing Xiao, Qiudong Meng.  (2023)  Adsorption of sulfadiazine on novel bilayer porous resin: Synergism of micropore filling and anion exchange.  Materials Science and Engineering B-Advanced Functional Solid-State Materials,      [PMID:] [10.1016/j.mseb.2023.117039]
2. Shizhuang Weng, Le Tang, Mengqing Qiu, Jinghong Wang, Yehang Wu, Rui Zhu, Cong Wang, Pan Li, Wen Sha, Dong Liang.  (2023)  Surface-enhanced Raman spectroscopy charged probes under inverted superhydrophobic platform for detection of agricultural chemicals residues in rice combined with lightweight deep learning network.  ANALYTICA CHIMICA ACTA,      [PMID:37179059] [10.1016/j.aca.2023.341264]
3. Lin Si, Quanbin Fu, Zekun Shi, Tingting Zhang, Qin Hou, Zhixiang Xu, Shiyun Ai.  (2023)  The fluorescent detection of biothiols and antimicrobial study based on copper(I) iodide coordination polymer.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2023.111228]
4. Rui Chen, Bao Dongmei, Jiaye Jiang, Chuanbo Sun, Han Chen, Min Zhang.  (2022)  Effect of 3-methoxysalicylaldehyde on transparency and mechanical properties of EP modified with aminopyridine-based DOPO derivative.  HIGH PERFORMANCE POLYMERS,      [PMID:] [10.1177/09540083221142758]
5. Xinlin Zha, Guilin Xu, Yi Xiong, Zhong Yan, Ke Liu, Mufang Li, Yuanli Chen, Jing Lu, Dong Wang.  (2022)  Modulating the Macroscopic Helicity of Poly(m-phenylenediamine) by Achiral Monomer Copolymerization.  ADVANCED FUNCTIONAL MATERIALS,  33  (3): (2211956).  [PMID:] [10.1002/adfm.202211956]
6. Junyi Tang, Yuanyuan Ren, Jiachun Feng.  (2022)  Fluorescence-color-changing biomimetic tough films with simultaneous shape-deformation triggered by pH.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.135932]
7. Yuntao Lei, H.Q. Nimal Gunaratne, Lili Jin.  (2022)  Design and synthesis of pyridinamide functionalized ionic liquids for efficient conversion of carbon dioxide into cyclic carbonates.  Journal of CO2 Utilization,      [PMID:] [10.1016/j.jcou.2022.101930]
8. Zhao Huaqi, Jin Xilang, Zhou Hongwei, Yang Zheng, Bai Haiyan, Yang Jin, Li Yulong, Ma Yiting, She Mengyao.  (2021)  Fabrication of carbon dots for sequential on–off-on determination of Fe3+ and S2− in solid-phase sensing and anti-counterfeit printing.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (30): (7473-7483).  [PMID:34647132] [10.1007/s00216-021-03709-6]
9. Yan-Xiong LIU, Long-Chun BIAN, Jie-Ren XIA, Qiu-E CAO.  (2021)  A Novel Ion-imprinted Polymer Based on Multi-walled Carbon Nanotubes for Solid Phase Extraction of Pd(II).  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,      [PMID:] [10.1016/S1872-2040(21)60114-7]
10. Ruzhen Cheng, Run Zou, Long He, Lei Liu, Chang Cao, Xinyuan Li, Xuhong Guo, Jun Xu.  (2021)  Effect of Aromatic Pendants in a Maleic Anhydride-co-Octadecene Polymer on the Precipitation of Asphaltenes Extracted from Heavy Crude Oil.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.1c01174]
11. Li Zishuai, Cheng Simin, Lin Qiaohong, Cao Wenbo, Yang Jing, Zhang Minmin, Shen Aijun, Zhang Wenpeng, Xia Yu, Ma Xiaoxiao, Ouyang Zheng.  (2021)  Single-cell lipidomics with high structural specificity by mass spectrometry.  Nature Communications,  12  (1): (1-10).  [PMID:34001877] [10.1038/s41467-021-23161-5]
12. Zhimin Wang, Fengjiao Zhang, Aimin Ning, Dongcan Lv, Guangce Jiang, Andong Song.  (2020)  Nanosilver supported on inert nano-diamond as a direct plasmonic photocatalyst for degradation of methyl blue.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2020.104912]
13. Cui-Ping Ye, Rui-Nan Wang, Xia Gao, Wen-Ying Li.  (2020)  CO2 Capture Performance of Supported Phosphonium Dual Amine-Functionalized Ionic Liquids@MCM-41.  ENERGY & FUELS,      [PMID:] [10.1021/acs.energyfuels.0c02547]
14. Rongxing Qiu, Xiaoyan Luo, Le Yang, Jiaran Li, Xiaoyan Chen, Cheng Peng, Jinqing Lin.  (2020)  Regulated Threshold Pressure of Reversibly Sigmoidal NH3 Absorption Isotherm with Ionic Liquids.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.9b06555]
15. Qinmei Zhang, Dan Li, Xiukai Cao, Haixin Gu, Wei Deng.  (2019)  Self-Assembled Microgels Arrays for Electrostatic Concentration and Surface-Enhanced Raman Spectroscopy Detection of Charged Pesticides in Seawater.  ANALYTICAL CHEMISTRY,      [PMID:31386345] [10.1021/acs.analchem.9b02106]
16. Cheng Xingan, Ye Jingmin, He Huiqing, Liu Zhanmei, Xu Chunbao (Charles), Wu Bo, Xiong Xialing, Shu Xugang, Jiang Xuhong, Qin Xiangjing.  (2018)  Synthesis, characterization and in vitro biological evaluation of two matrine derivatives.  Scientific Reports,  (1): (1-13).  [PMID:30356148] [10.1038/s41598-018-33908-8]
17. Liu Weixiang, Qin Yukun, Liu Song, Xing Ronge, Yu Huahua, Chen Xiaolin, Li Kecheng, Li Pengcheng.  (2018)  Synthesis of C-coordinated O-carboxymethyl chitosan metal complexes and evaluation of their antifungal activity.  Scientific Reports,  (1): (1-10).  [PMID:29556071] [10.1038/s41598-018-23283-9]
18. Guang-Zhen Zou, Hong Gao, Jian-Lan Liu, Shun-Ping Zhao, Zheng-Fang Tian, Xiao-Ming Ren.  (2013)  Novel dielectric relaxation behaviors driven by host–guest interactions in intercalated compounds of kaolinite with aminopyridine isomers.  RSC Advances,  (45): (23596-23603).  [PMID:] [10.1039/C3RA40579F]
19. Shuliang Chen, Li Zhao, Xinrong Li, Zhen Chen, Xianzhi Hu, Futing Zi.  (2024)  Constructing a cationic pyridine for the highly selective and efficient recovery of gold from waste printed circuit boards.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.149325]
20. Yi Chen, Zhu Ma, Tangjie Yu, Zhuowei Du, Wei You, Junbo Yang, Shanyue Hou, Yanlin Li, Qianyu Liu, Wenwen Li, Qian Zhang, Hao Du, Yixian Li, Fuchun Gou, Qiang Yang, Guoming Li, Yuelong Huang, Kuan Sun, Yaohua Mai, Wei Long.  (2024)  Interfacial passivation with 2-aminopyridine for effective perovskite solar cells.  MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING,      [PMID:] [10.1016/j.mssp.2024.108114]
21. Tiantian Wang, Yanli Zhou, Lantao Liu, Hui Dong, Yinghan Xu, Yidan Sun, Yaocun Yue, Jiaqing Tian, Maotian Xu.  (2025)  An immunobiosensor based on chelate-ring-containing iridium(III) complexes for electrochemiluminescence determination of TNF-α.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.114944]
22. Shunyan Ning, Sizhi Xu, Jiaxu Zheng, Shichang Zhang, Xiangbiao Yin, WenLong Li, Yuezhou Wei, Lifeng Chen.  (2025)  Enhanced separation of palladium from simulative high-level liquid waste using a silica-supported polymer functionalized with aminopyridine.  DESALINATION,      [PMID:] [10.1016/j.desal.2025.119060]
23. Li Jionghui, Zhang Weiquan, Chen Qing, Xiong Chunhua.  (2025)  Microwave-assisted synthesis of A novel modified polyacrylonitrile fiber and its adsorption performance for Cr(Ⅵ).  JOURNAL OF POROUS MATERIALS,      [PMID:] [10.1007/s10934-025-01889-5]
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