2-Deoxy-D-Ribose - Moligand™, 10mM in DMSO , CAS No.533-67-5

CAS: 533-67-5 Cat. No.: D424566 Peso molecular: 134.13 Beilstein Registry Number: 1721978 Número EC: 208-573-0

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

2-Deoxy-D-ribose, 97% | CHEBI:28816 | NSC-772796 | ASJSAQIRZKANQN-CRCLSJGQSA-N | BBL012499 | 2-Deoxy-D-ribose | 2-Deoxy-D-ribose, >=99.0% (TLC) | AM20100306 | 4-01-00-04181 (Beilstein Handbook Reference) | aldehydo-2-deoxy-D-ribose | D-erythro-Pentose, 2-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Sinónimos

2-Deoxy-D-ribose, 97% | CHEBI:28816 | NSC-772796 | ASJSAQIRZKANQN-CRCLSJGQSA-N | BBL012499 | 2-Deoxy-D-ribose | 2-Deoxy-D-ribose, >=99.0% (TLC) | AM20100306 | 4-01-00-04181 (Beilstein Handbook Reference) | aldehydo-2-deoxy-D-ribose | D-erythro-Pentose, 2-

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Reducing sugar used to study processes of oxidative stress and glycation in vivo and in vitro . Induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Endothelial-cell chemoattractant and angiogenesis-inducing factor

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Sonrisas canónicas: C(C=O)C(C(CO)O)O
• IUPAC Name: (3S,4R)-3,4,5-trihydroxypentanal
• InChIKey: ASJSAQIRZKANQN-CRCLSJGQSA-N
• INCHI: 1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m0/s1
• Isómeros SMILES: C(C=O)[C@@H]([C@@H](CO)O)O
• WGK Alemania: 3
• RTECS: SB7230000
• Peso molecular: 134.13
• Beilstein: 1721978
• Reaxy-Rn: 1904591
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1904591&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbonyl compounds
        • Level5 Aldehydes
          • Level6 Beta-hydroxy aldehydes

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbonyl compounds
• Intermediate Tree Nodes: Aldehydes
• Direct Parent: Beta-hydroxy aldehydes
• Alternative Parents: Alpha-hydrogen aldehydes Secondary alcohols Polyols Short-chain aldehydes Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Beta-hydroxy aldehyde - Alpha-hydrogen aldehyde - Secondary alcohol - Polyol - Organic oxide - Hydrocarbon derivative - Short-chain aldehyde - Primary alcohol - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as beta-hydroxy aldehydes. These are organic compounds containing an aldehyde substituted with a hydroxy group on the second carbon atom.
• External Descriptors: deoxypentose

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Hygroscopic
• Rotación específica [α]: -56 ° (C=1, H2O)
• Punto de fusión (°C): 91°C
• Peso molecular: 134.130 g/mol
• XLogP3: -2.300
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 134.058 Da
• Monoisotopic Mass: 134.058 Da
• Topological Polar Surface Area: 77.800 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 83.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Binbin Zhang, Jiao Ma, Kaide Ou, Xin Cong, Hao Zou, Yonggui Liao, Yajiang Yang, Hong Wang.  (2023)  Luminescent lanthanide metallogel as a sensor array to efficiently discriminate various saccharides.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2023.121447]

2. Zong-Ying Li, Hong-Xia Zhang, Tian-Sheng He, Hong-Xin Jiang, Xiao-Wei Liu, Li-Na Zhu, Xiao-Zeng Li, De-Ming Kong.  (2022)  A multifunctional and water-stable Cd (II) coordination polymer: Sensitive detection of roxarsone, Fe3+, CrO42− and Cr2O72− in aqueous media.  INORGANICA CHIMICA ACTA,      [PMID:] [10.1016/j.ica.2022.121334]

3. Shi Ning, Liu Qiying, Cen Hu, Ju Rongmei, He Xiong, Ma Longlong.  (2019)  Formation of humins during degradation of carbohydrates and furfural derivatives in various solvents.  Biomass Conversion and Biorefinery,  10  (2): (277-287).  [PMID:] [10.1007/s13399-019-00414-4]

4. Li-Hong Tan, Dan Zhang, Gang Wang, Bao Yu, Sheng-Ping Zhao, Jian-Wei Wang, Ling Yao, Wei-Guo Cao.  (2015)  Comparative analyses of flavonoids compositions and antioxidant activities of Hawk tea from six botanical origins.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2015.11.035]

5. Yuanfeng Wang, Yangyang Liu, Jianglei Huo, Tingtong Zhao, Jian Ren, Xinlin Wei.  (2013)  Effect of different drying methods on chemical composition and bioactivity of tea polysaccharides.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:24120964] [10.1016/j.ijbiomac.2013.10.006]

6. Yuanfeng Wang, Zhiwei Yang, Xinlin Wei.  (2012)  Antioxidant activities potential of tea polysaccharide fractions obtained by ultra filtration.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:22230610] [10.1016/j.ijbiomac.2011.12.028]

7. Luo Laipeng, Ding Chenkun, Zhu Qinting, Liu Lei, Wang Ping, Wang Qiang, Yu Yuanyuan.  (2024)  A Novel Cotton Scouring Using Pectinase in Combination with Fenton System.  FIBERS AND POLYMERS,  25  (7): (2669-2682).  [PMID:] [10.1007/s12221-024-00612-6]

8. Yanhui Wang, Huayu Fu, Bangqi Huang, Ziyang Liang, Yijun Shen, Yulan Wang, Jun Wu, Yi Zhao.  (2024)  Hollow mesoporous Prussian blue nanoenzymes as Rapamycin carrier for targeted treatment of ischemia/reperfusion-induced acute kidney injury through pro-mitophagy and oxidative stress alleviation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.155684]

9. Yushi Wei, Jianmei Wu, Xi Peng, Xing Hu, Deming Gong, Guowen Zhang.  (2024)  Protein glycosylation inhibitory effects and mechanisms of phloretin and phlorizin.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.104971]

10. Daihong Gao, Denghao Ouyang, Yuchen Bai, Xuebing Zhao.  (2023)  Synthesis and Computational Investigation of Antioxidants Prepared by Oxidative Depolymerization of Lignin and Aldol Condensation of Aromatic Aldehydes.  ChemSusChem,  16  (12): (e202300208).  [PMID:37040093] [10.1002/cssc.202300208]

11. Huayu Fu, Yanhui Wang, Bangqi Huang, Zonghao Liang, Yumin Li, Zhong Cao, Jun Wu, Yi Zhao.  (2025)  Tannic acid‑cerium nanoenzymes serve as broad-spectrum antioxidants to alleviate acute kidney injury by modulating macrophage polarization, mitophagy and endoplasmic reticulum stress.  JOURNAL OF CONTROLLED RELEASE,      [PMID:39971251] [10.1016/j.jconrel.2025.02.038]