2′-Deoxyguanosine 5′-diphosphate sodium salt - Moligand™,≥98% , CAS No.102783-74-4

CAS: 102783-74-4 Cat. No.: D119530 Peso molecular: 427.20(free acid) Número EC: 634-395-1 PubChem CID: 135742697

GRADE & PURITY Moligand™, ≥98%

Synonyms

dGDP | A855591 | Guanosine5'-(trihydrogen diphosphate), 2'-deoxy-, trisodium salt | 2'-Deoxyguanosine-5'-diphosphate trisodium salt | Sodium 2'-deoxyguanosine 5'-(trihydrogen diphosphate) (3:1) | 2'-Deoxyguanosine-5'-diphosphate trisodium | trisodium;[[(2

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

2′-Deoxyguanosine 5′-diphosphate (dGDP) is a nucleotide with guanine base, deoxyribose and two phosphate.

Specifications

Sinónimos

dGDP | A855591 | Guanosine5'-(trihydrogen diphosphate), 2'-deoxy-, trisodium salt | 2'-Deoxyguanosine-5'-diphosphate trisodium salt | Sodium 2'-deoxyguanosine 5'-(trihydrogen diphosphate) (3:1) | 2'-Deoxyguanosine-5'-diphosphate trisodium | trisodium;[[(2

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

2′-Deoxyguanosine 5′-diphosphate (dGDP) inhibits xanthine phosphoribosyl transferase (XPRT) and hypoxanthine-guanine phosphoribosyl transferase (HGPRT).

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504773434
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773434
• Sonrisas canónicas: C1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OP(=O)([O-])[O-])O.[Na+].[Na+].[Na+]
• IUPAC Name: trisodium;[[(2R,3S,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate
• InChIKey: DRQVDNDKEVNMJT-BIHLCPNHSA-K
• INCHI: 1S/C10H15N5O10P2.3Na/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20;;;/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17);;;/q;3*+1/p-3/t4-,5+,6+;;;/m0.../s1
• Isómeros SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N)COP(=O)([O-])OP(=O)([O-])[O-])O.[Na+].[Na+].[Na+]
• WGK Alemania: 3
• PubChem CID: 135742697
• Peso molecular: 427.20(free acid)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleotides
      • Subclass Purine deoxyribonucleotides
        • Level5 Purine deoxyribonucleoside diphosphates
          • Level6 Purine 2'-deoxyribonucleoside diphosphates

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleotides
• Subclass: Purine deoxyribonucleotides
• Intermediate Tree Nodes: Purine deoxyribonucleoside diphosphates
• Direct Parent: Purine 2'-deoxyribonucleoside diphosphates
• Alternative Parents: 6-oxopurines Hypoxanthines Organic pyrophosphates Pyrimidones Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Vinylogous amides Heteroaromatic compounds Oxolanes Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives Organic oxides Organic zwitterions Organic sodium salts
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine 2'-deoxyribonucleoside diphosphate - 6-oxopurine - Hypoxanthine - Organic pyrophosphate - Imidazopyrimidine - Purine - Aminopyrimidine - Pyrimidone - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Vinylogous amide - Azole - Imidazole - Heteroaromatic compound - Oxolane - Secondary alcohol - Oxacycle - Organic alkali metal salt - Azacycle - Organoheterocyclic compound - Primary amine - Organonitrogen compound - Organic salt - Alcohol - Organic nitrogen compound - Hydrocarbon derivative - Organic sodium salt - Organic oxide - Organooxygen compound - Organic zwitterion - Organic oxygen compound - Amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine 2'-deoxyribonucleoside diphosphates. These are purine nucleotides with diphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water
• Sensibilidad: Moisture sensitive
• Punto de fusión (°C): >178°C
• Peso molecular: 493.150 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 5
• Exact Mass: 492.975 Da
• Monoisotopic Mass: 492.975 Da
• Topological Polar Surface Area: 237.000 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 709.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3

Referencias

1. Dongmei Tang, Yijun Chen, Hao Chen, Tingting Jia, Qiang Chen, Yamei Yu.  (2023)  Multiple enzymatic activities of a Sir2-HerA system cooperate for anti-phage defense.  MOLECULAR CELL,      [PMID:38096825] [10.1016/j.molcel.2023.11.010]

2. Zhifeng Zeng, Zeyu Hu, Ruiliang Zhao, Jikai Rao, Mario Rodríguez Mestre, Yanqiu Liu, Shunhang Liu, Hao Feng, Yu Chen, Huan He, Nuo Chen, Jinshui Zheng, Donghai Peng, Min Luo, Qunxin She, Rafael Pinilla-Redondo, Wenyuan Han.  (2025)  Base-modified nucleotides mediate immune signaling in bacteria.  SCIENCE,      [PMID:39977546] [10.1126/science.ads6055]