2-Fluoropalmitic acid - ≥98% , CAS No.16518-94-8

CAS: 16518-94-8 Cat. No.: F647550 Peso molecular: 274.41

GRADE & PURITY ≥98%

Synonyms

HMS1989G17 | BML3-C06 | 2-fluoropalmitic acid | KBio3_000270 | NCGC00161355-01 | CHEBI:94978 | HMS1791G17 | 2-FLUOROPALMITICACID | CBiol_002000 | HMS1361G17 | KBioSS_000135 | SCHEMBL337296 | Bio2_000615 | Bio1_001264 | KBio2_000135 | NCGC00161355-02 | SR-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invasion of glioma cell lines.

Form:Solid

Specifications

Sinónimos

HMS1989G17 | BML3-C06 | 2-fluoropalmitic acid | KBio3_000270 | NCGC00161355-01 | CHEBI:94978 | HMS1791G17 | 2-FLUOROPALMITICACID | CBiol_002000 | HMS1361G17 | KBioSS_000135 | SCHEMBL337296 | Bio2_000615 | Bio1_001264 | KBio2_000135 | NCGC00161355-02 | SR-

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

2-Fluoropalmitic acid, an acyl-CoA synthetase inhibitor, acts as a candidate anti-glioma agent. 2-Fluoropalmitic acid suppresses the viability and stem-like phenotype of glioma stem cells (GSCs). 2-Fluoropalmitic acid also inhibits proliferation and invas

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCCCCCCC(C(=O)O)F
• IUPAC Name: 2-fluorohexadecanoic acid
• InChIKey: JGRIJJOLCNCSNX-UHFFFAOYSA-N
• INCHI: 1S/C16H31FO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)
• Isómeros SMILES: CCCCCCCCCCCCCCC(C(=O)O)F
• CAS alternativo: 16518-94-8
• Número NSC: 158288
• Términos de entrada MeSH: 2-fluorohexadecanoic acid;2-fluoropalmitic acid;DL-alpha-fluoropalmitic acid
• Peso molecular: 274.41
• Reaxy-Rn: 1911045
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1911045&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acids and conjugates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acids and conjugates
• Intermediate Tree Nodes: Not available
• Direct Parent: Long-chain fatty acids
• Alternative Parents: Halogenated fatty acids Alpha-halocarboxylic acids Monocarboxylic acids and derivatives Carboxylic acids Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Long-chain fatty acid - Halogenated fatty acid - Alpha-halocarboxylic acid - Alpha-halocarboxylic acid or derivatives - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organofluoride - Organohalogen compound - Organic oxide - Organic oxygen compound - Carbonyl group - Alkyl fluoride - Alkyl halide - Organooxygen compound - Hydrocarbon derivative - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as long-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
• External Descriptors: Halogenated fatty acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Mapt Microtubule-associated protein tau (6 Activities)

Discover Target: Mapt

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (364.42 mM; Need ultrasonic)
• Peso molecular: 274.410 g/mol
• XLogP3: 7.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 274.231 Da
• Monoisotopic Mass: 274.231 Da
• Topological Polar Surface Area: 37.300 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 207.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1