2-Hydroxychalcone - Moligand™, 10 mM in DMSO , CAS No.644-78-0

CAS: 644-78-0 Cat. No.: H1495233 Peso molecular: 224.26 Beilstein Registry Number: 8(4)1388 Número EC: 211-422-1

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Protected from light,Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

2-hydroxychalcone, a natural flavonoid, is a potent antioxidant, inhibiting lipid peroxidation. 2-Hydroxychalcone induces apoptosis by Bcl-2 downregulation. 2-Hydroxychalcone inhibits the activation of NF-kB.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Protected from light, Argon charged, Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Isómeros SMILES: C1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC=C2O
• Peso molecular: 224.26
• Beilstein: 8(4)1388
• Reaxy-Rn: 147424
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=147424&ln=

Propiedades químicas y físicas

• Punto de fusión (°C): ca 154° dec.

Referencias

1. Jianglin Zhang, Fan Yang, Xia Sun, Lingyu Gao, Jing Yan, Xiuxian Chen, Yuhua Gu, Shuaijie Song, Fuliang Hu, Xu'’ai Lin, Simon Duttwyler, Hao Cheng, Stijn van der Veen.  (2025)  2-Hydroxychalcone is a gonococcal-specific antimicrobial with activity against elongation factor Tu and butanediol dehydrogenase.  LIFE SCIENCES,      [PMID:41015385] [10.1016/j.lfs.2025.123994]