2'-MeCCPA - ≥98%(HPLC) , CAS No.205171-12-6

CAS: 205171-12-6 Cat. No.: M287948 Peso molecular: 383.83

GRADE & PURITY ≥98%(HPLC)

Synonyms

2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol | 2-[2-chloro-6-(cyclopentylamino)-9-purinyl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol | PD025783 | 2-Chloro-N-cyclopentyl-9-(2-C-methylpentofuranosyl)-9H-purin-6-ami

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

2'-MeCCPA is a potent and selective A1 adenosine receptors (A1AR) agonist. 2'-MeCCPA efficiently inhibits cAMP modulation in both direct pathway medium spiny neurons (dMSNs) and indirect pathway medium spiny neurons (iMSNs)。

Specifications

Sinónimos

2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3, 4-diol | 2-[2-chloro-6-(cyclopentylamino)-9-purinyl]-5-(hydroxymethyl)-3-methyloxolane-3, 4-diol | PD025783 | 2-Chloro-N-cyclopentyl-9-(2-C-methylpentofuranosyl)-9H-purin-6-ami

Especificaciones y pureza

≥98%(HPLC)

Mecanismos bioquímicos y fisiológicos

Potent and highly selective agonist at A1adenosine receptors (Kivalues are 3.3, 9580, 37600 and 1150 nM for human recombinant A1, A2A, A2Band A3receptors respectively). Acts as a full agonist; inhibits forskolin-stimulated adenylyl cyclase activity in rat

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

AGONIST

Pureza

≥98%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: CC1(C(C(OC1N2C=NC3=C(N=C(N=C32)Cl)NC4CCCC4)CO)O)O
• IUPAC Name: 2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol
• InChIKey: MMPAUXMIDJWGFO-UHFFFAOYSA-N
• INCHI: 1S/C16H22ClN5O4/c1-16(25)11(24)9(6-23)26-14(16)22-7-18-10-12(19-8-4-2-3-5-8)20-15(17)21-13(10)22/h7-9,11,14,23-25H,2-6H2,1H3,(H,19,20,21)
• Isómeros SMILES: CC1(C(C(OC1N2C=NC3=C(N=C(N=C32)Cl)NC4CCCC4)CO)O)O
• Peso molecular: 383.83
• Reaxy-Rn: 25852658
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25852658&ln=

Propiedades químicas y físicas

• Solubilidad: Solvent:DMSO, Max Conc. mg/mL: 9.6, Max Conc. mM: 25