3-{[(2,6-dichlorophenyl)methyl]amino}-6,7-dimethoxy-1H,4H-indeno[1,2-c]pyrazol-4-one - Moligand™ , Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 1, CAS No.D609015, Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 1

CAS: D609015 Cat. No.: D609015 PubChem CID: 45375987

GRADE & PURITY Moligand™

Synonyms

compound 27

Storage

Room temperature

Specifications

Sinónimos

compound 27

Especificaciones y pureza

Moligand™

Condiciones de almacenamiento de almacenamiento

Room temperature

Grado

Moligand™

Tipo de acción

INHIBITOR

Mecanismo de acción

Inhibitor of eukaryotic translation initiation factor 2 alpha kinase 1

Nombres e identificadores

• Sonrisas canónicas: COc1cc2c3[nH]nc(c3C(=O)c2cc1OC)NCc1c(Cl)cccc1Cl
• IUPAC Name: 3-{[(2,6-dichlorophenyl)methyl]amino}-6,7-dimethoxy-1H,4H-indeno[1,2-c]pyrazol-4-one
• InChIKey: UUDNGLPFGYJJQX-UHFFFAOYSA-N
• INCHI: 1S/C19H15Cl2N3O3/c1-26-14-6-9-10(7-15(14)27-2)18(25)16-17(9)23-24-19(16)22-8-11-12(20)4-3-5-13(11)21/h3-7H,8H2,1-2H3,(H2,22,23,24)
• Isómeros SMILES: COC1=C(C=C2C(=C1)C3=C(C2=O)C(=NN3)NCC4=C(C=CC=C4Cl)Cl)OC
• PubChem CID: 45375987

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Benzene and substituted derivatives
      • Subclass Halobenzenes
        • Level5 Chlorobenzenes
          • Level6 Dichlorobenzenes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Benzene and substituted derivatives
• Subclass: Halobenzenes
• Intermediate Tree Nodes: Chlorobenzenes
• Direct Parent: Dichlorobenzenes
• Alternative Parents: Benzylamines Aryl ketones Anisoles Secondary alkylarylamines Alkyl aryl ethers Imidolactams Aryl chlorides Vinylogous amides Pyrazoles Heteroaromatic compounds Azacyclic compounds Organochlorides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Anisole - Benzylamine - 1,3-dichlorobenzene - Phenol ether - Aryl ketone - Alkyl aryl ether - Secondary aliphatic/aromatic amine - Aryl chloride - Aryl halide - Imidolactam - Azole - Heteroaromatic compound - Pyrazole - Vinylogous amide - Ketone - Ether - Azacycle - Organoheterocyclic compound - Secondary amine - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

EIF2AK1 Tchem Eukaryotic translation initiation factor 2-alpha kinase 1 (2 Activities)

Discover Target: EIF2AK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mecanismos de acción