Determine the necessary mass, volume, or concentration for preparing a solution.
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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488191226 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488191226 |
| Sonrisas canónicas | COC1=C(C=C(C=C1)C=CC(=O)O)OC |
| IUPAC Name | (E)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid |
| InChIKey | HJBWJAPEBGSQPR-GQCTYLIASA-N |
| INCHI | 1S/C11H12O4/c1-14-9-5-3-8(4-6-11(12)13)7-10(9)15-2/h3-7H,1-2H3,(H,12,13)/b6-4+ |
| Isómeros SMILES | COC1=C(C=C(C=C1)/C=C/C(=O)O)OC |
| WGK Alemania | 3 |
| Peso molecular | 208.21 |
| Beilstein | 10(1)212 |
| Reaxy-Rn | 1533435 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1533435&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Clase | Cinnamic acids and derivatives |
| Subclass | Hydroxycinnamic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Coumaric acids and derivatives |
| Alternative Parents | Cinnamic acids Dimethoxybenzenes Styrenes Phenoxy compounds Anisoles Alkyl aryl ethers Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Cinnamic acid - Coumaric acid or derivatives - O-dimethoxybenzene - Dimethoxybenzene - Phenoxy compound - Anisole - Methoxybenzene - Styrene - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Ether - Organic oxygen compound - Carbonyl group - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as coumaric acids and derivatives. These are aromatic compounds containing Aromatic compounds containing a cinnamic acid moiety (or a derivative thereof) hydroxylated at the C2 (ortho-), C3 (meta-), or C4 (para-) carbon atom of the benzene ring. |
| External Descriptors | methoxycinnamic acid |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jan 27, 2026 | D100558 | |
| Certificate of Analysis | Dec 10, 2025 | D100558 | |
| Certificate of Analysis | Dec 10, 2025 | D100558 | |
| Certificate of Analysis | Dec 10, 2025 | D100558 | |
| Certificate of Analysis | Apr 27, 2022 | D100558 | |
| Certificate of Analysis | Dec 16, 2021 | D100558 | |
| Certificate of Analysis | Dec 16, 2021 | D100558 | |
| Certificate of Analysis | Dec 16, 2021 | D100558 |
| Punto de fusión (°C) | 181-183°C |
|---|---|
| Peso molecular | 208.210 g/mol |
| XLogP3 | 1.800 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 208.074 Da |
| Monoisotopic Mass | 208.074 Da |
| Topological Polar Surface Area | 55.800 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 237.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xiaoxue Pan, Junyan Wei, Min Wang, Jie Zhang, Zhiming Xu, Haojie Wei, Nami Lai, Kainan Nian, Rui Zhang, Xuesheng Zhang. (2023) Comparative studies of transformation behaviors and mechanisms of halophenols in multiple chemical oxidative systems. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:36690111] [10.1016/j.scitotenv.2023.161756] |
| 2. Xijuan Tu, Fengjie Yu, Qian Jin, Chunping Du, Jiaxu Chen, Ji Yang, Yuchang He, Shaokang Huang, Wenbin Chen. (2022) A Simple High-Throughput Field Sample Preparation Method Based on Matrix-Induced Sugaring-Out for the Simultaneous Determination of 5-Hydroxymethylfurfural and Phenolic Compounds in Honey. MOLECULES, 27 (23): (8373). [PMID:36500464] [10.3390/molecules27238373] |
| 3. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2022) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] [10.1039/D2FO02233H] |
| 4. Denghao Ouyang, Hongmei Chen, Nan Liu, Jingzhi Zhang, Xuebing Zhao. (2021) Insight into the negative effects of lignin on enzymatic hydrolysis of cellulose for biofuel production via selective oxidative delignification and inhibitive actions of phenolic model compounds. RENEWABLE ENERGY, [PMID:] [10.1016/j.renene.2021.12.036] |
| 5. Fengjie Yu, Jianing Zhang, Yunmin Tao, Chunping Du, Wenchao Yang, Wenbin Chen, Xijuan Tu. (2021) High-throughput subzero-temperature assisted homogenous liquid-liquid extraction for the fast sample preparation of multiple phenolic compounds in propolis. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, [PMID:34147873] [10.1016/j.jchromb.2021.122823] |
| 6. Houmei Liu, Zhan Li, Makoto Takafuji, Hirotaka Ihara, Hongdeng Qiu. (2017) Octadecylimidazolium ionic liquid-modified magnetic materials: Preparation, adsorption evaluation and their excellent application for honey and cinnamon. FOOD CHEMISTRY, [PMID:28372166] [10.1016/j.foodchem.2017.02.080] |
| 7. Houmei Liu, Xiaojing Liang, Xusheng Wang, Yong Guo, Xia Liu. (2014) Polyelectrolyte assembled graphene oxide coated silica composite as sorbent for solid-phase extraction of cinnamic acid and its derivatives. RSC Advances, 5 (6): (4420-4427). [PMID:] [10.1039/C4RA13331E] |
| 8. Peiliang Xiao, Suoqin Zhang, Huayu Ma, Aijun Zhang, Xiaoli Lv, Liangyu Zheng. (2013) Stereoselective synthesis of caffeic acid amides via enzyme-catalyzed asymmetric aminolysis reaction. JOURNAL OF BIOTECHNOLOGY, [PMID:24056082] [10.1016/j.jbiotec.2013.09.004] |
| 9. Yupei Sun, Yanhui Yi, Bingkang Wang, Jinrong Li, Feng Zhao, Jianzeng Xin, Sheng Liu. (2026) Design, synthesis and anti-tumor activation of β-carboline alkaloids derivatives from Picrasma quassioides. FITOTERAPIA, [PMID:] [10.1016/j.fitote.2026.107209] |