3′,5′-Dimethoxy-4′-hydroxyacetophenone - 10mM in DMSO , CAS No.2478-38-8

CAS: 2478-38-8 Cat. No.: D422851 Peso molecular: 196.2 Beilstein Registry Number: 1966119 Número EC: 219-610-5
Disponible para pedir
GRADE & PURITY 10mM in DMSO
Synonyms
4-Hydroxy-3,5-dimethoxyacetophennone | EN300-112111 | NCGC00095819-01 | SDCCGMLS-0066948.P001 | Acetosyringon | SPBio_000418 | 4-Hydroksy-3',5'-dwumetoksyacetofenon [Polish] | Acetophenone, 3,5-dimethoxy-4-hydroxy- | 1-(4-hydroxy-3,5-dimethoxyphenyl)ethan
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Estado
Price
Qty
1ml
D422851-1ml
1
31,90US$
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

3',5'-Dimethoxy-4'-hydroxyacetophenone is used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents in vitro. It is a naturally occuring compound found in plants and used in plant-pathogen recognition.
A buffer also known as acetosyringone that is used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents in vitro.

Specifications

Sinónimos
4-Hydroxy-3, 5-dimethoxyacetophennone | EN300-112111 | NCGC00095819-01 | SDCCGMLS-0066948.P001 | Acetosyringon | SPBio_000418 | 4-Hydroksy-3', 5'-dwumetoksyacetofenon [Polish] | Acetophenone, 3, 5-dimethoxy-4-hydroxy- | 1-(4-hydroxy-3, 5-dimethoxyphenyl)ethan
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Naturally occurring phenolic compound found in plants and used in plant-pathogen recognition. Effective inducer of the virulence genes of Agrobacterium tumefaciens .
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores
Sonrisas canónicasCC(=O)C1=CC(=C(C(=C1)OC)O)OC
IUPAC Name1-(4-hydroxy-3,5-dimethoxyphenyl)ethanone
InChIKeyOJOBTAOGJIWAGB-UHFFFAOYSA-N
INCHI1S/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H3
Isómeros SMILES CC(=O)C1=CC(=C(C(=C1)OC)O)OC
WGK Alemania 2
RTECS AM8440000
Peso molecular 196.2
Beilstein 1966119
Reaxy-Rn 1966119
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1966119&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClaseOrganooxygen compounds
SubclassCarbonyl compounds
Intermediate Tree Nodes Ketones - Aryl ketones - Phenylketones
Direct ParentAlkyl-phenylketones
Alternative Parents Methoxyphenols  Dimethoxybenzenes  Acetophenones  Phenoxy compounds  Benzoyl derivatives  Aryl alkyl ketones  Anisoles  Alkyl aryl ethers  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Alkyl-phenylketone - M-dimethoxybenzene - Dimethoxybenzene - Methoxyphenol - Acetophenone - Phenoxy compound - Anisole - Methoxybenzene - Aryl alkyl ketone - Benzoyl - Phenol ether - Alkyl aryl ether - Phenol - Benzenoid - Monocyclic benzene moiety - Ether - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group.
External Descriptors phenols - dimethoxybenzene - acetophenones
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Agrobacterium tumefaciens (620 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1210 (27553 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Índice de refracción1.53
Punto de ebullición (°C)335 °C
Punto de fusión (°C)124.0-127.0°C
Peso molecular196.200 g/mol
XLogP30.200
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass196.074 Da
Monoisotopic Mass196.074 Da
Topological Polar Surface Area55.800 Ų
Heavy Atom Count14
Formal Charge0
Complexity190.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Daihong Gao, Denghao Ouyang, Xuebing Zhao.  (2023)  Controllable oxidative depolymerization of lignin to produce aromatic aldehydes and generate electricity under mild conditions with direct biomass fuel cells as flexible reactors.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.147874]
2. Chen Ying, Zhang Meng, Zhang Wenli, Wang Yamin, Zhang Hua, Yang Liu, Yu Longjiang, Fu Chunhua.  (2023)  miR5298b regulated taxol biosynthesis by acting on TcNPR3, resulting in an alleviation of the strong inhibition of the TcNPR3-TcTGA6 complex in Taxus chinensis.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37482165] [10.1016/j.ijbiomac.2023.125909]
3. Jia Juan, Xue Ping, Liu Xueping, Xu Chongrui, Gu Yaohua, Li Peng.  (2023)  Laccase–mediator co-immobilized doped-HKUST-1 cellulose composite beads and their application for the biodegradation of carbazole.  Reaction Chemistry & Engineering,  (9): (2342-2352).  [PMID:] [10.1039/D3RE00253E]
4. Yajie Zuo, Siying Zhu, Yi Liu, Jingjing Zhao, Shiyi Zhang, Chongmin Zhong.  (2023)  Quantitative Methylation of Lignin Monomers Using Tetrabutylammonium Hydroxide and MeI and Applications in Organic Synthesis.  ACS Omega,      [PMID:36844551] [10.1021/acsomega.2c07920]
5. Yifei Leng, Feiyu Liu, Huiping Cai, Fengyi Chang, Wen Xiong, Shushi Huang, Jun Wang.  (2022)  Mechanism of norfloxacin transformation by horseradish peroxidase and various redox mediated by humic acid and microplastics.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:36270366] [10.1016/j.scitotenv.2022.159528]
6. Yang Guangxu, Gong Zhenggang, Luo Xiaolin, Shuai Li.  (2022)  Revisiting alkaline cupric oxide oxidation method for lignin structural analysis.  Frontiers in Bioengineering and Biotechnology,      [PMID:36159682] [10.3389/fbioe.2022.1002145]
7. Cong Chen, Fei Yu, Xinli Wen, Shuna Chen, Kaixi Wang, Feiquan Wang, Jianming Zhang, Yuanyuan Wu, Puming He, Youying Tu, Bo Li.  (2022)  Characterization of a new (Z)-3:(E)-2-hexenal isomerase from tea (Camellia sinensis) involved in the conversion of (Z)-3-hexenal to (E)-2-hexenal.  FOOD CHEMISTRY,      [PMID:35183969] [10.1016/j.foodchem.2022.132463]
8. Li-Xian Zhu, Qin-Bao Lin, Jia-Yi Li, Hong-Mei Zhu, Hong-Sheng Ma, Huai-Ning Zhong, Jing-Jing Pan.  (2019)  Sources of potassium permanganate consumption for food contact paper.  Food Packaging and Shelf Life,      [PMID:] [10.1016/j.fpsl.2019.100319]
9. Kai Wu, Wenjun Ying, Zhengjun Shi, Haiyan Yang, Zhifeng Zheng, Jiayan Zhang, Jing Yang.  (2018)  Fenton Reaction-Oxidized Bamboo Lignin Surface and Structural Modification to Reduce Nonproductive Cellulase Binding and Improve Enzyme Digestion of Cellulose.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.7b04191]
10. Shiyang Yu, Shanshan Tang, Jitao Lv, Feifei Li, Zichun Huang, Lixia Zhao, Dong Cao, Yawei Wang.  (2024)  High throughput identification of carbonyl compounds in natural organic matter by directional derivatization combined with ultra-high resolution mass spectrometry.  WATER RESEARCH,      [PMID:38759284] [10.1016/j.watres.2024.121769]
11. Yun Tian, Mengqiao Gao, Zhiyang Tang, Fukun Li, Qiang Zeng, Jinxing Long, Xuehui Li.  (2024)  In-situ generated hydrogen for selective hydrogenolysis of lignin catalyzed by Mg-Al mixed oxides with nested Ni nanoparticles.  JOURNAL OF CATALYSIS,      [PMID:] [10.1016/j.jcat.2024.115833]
12. Feixiong Zheng, Zhangting Xu, Xiaoji Deng, Xiaoyuan Wang, Yiming Sun, Xiaoxia Shen, Zhenming Yu.  (2025)  Genome-Wide Transcriptome Analysis Reveals GRF Transcription Factors Involved in Methyl Jasmonate-Induced Flavonoid Biosynthesis in Hedera helix.  Plants-Basel,  14  (14): (2094).  [PMID:40733331] [10.3390/plants14142094]
13. Chong-Min Zhong, Fenglian Lv, Yajie Zuo, Zhe Cui, Siying Zhu, Yanqing Li, Yizhou Bian, Miaofeng Ma.  (2025)  Methyl derivatives of lignin phenols reveal systematic underestimation in characterization of soil lignin via conventional silyl derivatives.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.114386]
14. Feixiong Zheng, Zhangting Xu, Xiaoji Deng, Yiming Sun, Jaime A. Teixeira da Silva, Xiaoxia Shen, Zhenming Yu.  (2025)  Comprehensive identification of aquaporins under salt stress, and functional characterization of DoTIP1-1 in Dendrobium officinale.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:41453282] [10.1016/j.plaphy.2025.110952]
15. Tianyin Huang, Yifan Yu, Wentao Zhang, Yue Zhao, Yiliang Tao, Wenguang Huang, Bingdang Wu.  (2026)  Molecular orbital-guided design of laccase–mediator systems for antibiotic removal in the presence of humic acid.  BIORESOURCE TECHNOLOGY,      [PMID:41513177] [10.1016/j.biortech.2026.133957]
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