≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Argon charged,Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
4,4′-Diaminodiphenyl sulfide is a diaminodiphenyl analog. On oral administration to rats, it induces haematological and pathological changes indicative of erythrocyte destruction. It has been reported to generate hydrogen peroxide in erythrocytes in vitro. Enzymatic oxidation of 4,4′-diaminodiphenyl sulfide to their sulfoxide derivatives in guinea pig liver homogenates has been reported.
| Sonrisas canónicas | C1=CC(=CC=C1N)SC2=CC=C(C=C2)N |
|---|---|
| IUPAC Name | 4-(4-aminophenyl)sulfanylaniline |
| InChIKey | ICNFHJVPAJKPHW-UHFFFAOYSA-N |
| INCHI | 1S/C12H12N2S/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,13-14H2 |
| Isómeros SMILES | C1=CC(=CC=C1N)SC2=CC=C(C=C2)N |
| WGK Alemania | 3 |
| RTECS | BY9625000 |
| Peso molecular | 216.3 |
| Beilstein | 1875513 |
| Reaxy-Rn | 1875513 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1875513&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organosulfur compounds |
| Clase | Thioethers |
| Subclass | Aryl thioethers |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Diarylthioethers |
| Alternative Parents | Thiophenol ethers Aniline and substituted anilines Sulfenyl compounds Primary amines Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Diarylthioether - Aniline or substituted anilines - Thiophenol ether - Benzenoid - Monocyclic benzene moiety - Sulfenyl compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as diarylthioethers. These are organosulfur compounds containing a thioether group that is substituted by two aryl groups. |
| External Descriptors | substituted aniline |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 J2129410 | Certificate of Analysis | Aug 11, 2025 | D101166 |
| B2514161 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| B2514162 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| B2514163 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| B2514164 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| B2514165 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| B2514166 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| D2616126 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| F2602039 | Certificate of Analysis | Jan 22, 2025 | D101166 |
| E2422238 | Certificate of Analysis | May 16, 2024 | D101166 |
| L2410071 | Certificate of Analysis | May 16, 2024 | D101166 |
| K2205211 | Certificate of Analysis | Oct 26, 2022 | D101166 |
| K2205228 | Certificate of Analysis | Oct 26, 2022 | D101166 |
| K2205229 | Certificate of Analysis | Oct 26, 2022 | D101166 |
| Solubilidad | Insoluble in water; Very soluble in Ether,Alcohol |
|---|---|
| Sensibilidad | Sensitive to light; sensitive to humidity; sensitive to air |
| Punto de fusión (°C) | 105-107°C |
| Peso molecular | 216.300 g/mol |
| XLogP3 | 2.200 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 216.072 Da |
| Monoisotopic Mass | 216.072 Da |
| Topological Polar Surface Area | 77.300 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 162.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Zirun Chen, Junlong Huang, Yin Cui, Ruowen Fu. (2022) Precisely tailored morphology of polyimine for simple synthesis of metal sulfide/carbon flower-like superstructures. CARBON, [PMID:] [10.1016/j.carbon.2022.01.021] |
| 2. Tuo Xin, Qiuju Xu, Xiangcheng Yuan, Qi Zhang, Meinan Liu, Jinzhang Liu. (2022) Bendable Aqueous Zinc-Ion Hybrid Energy Storage Device Using Poly(4,4’-thiodianiline)-Modified Nanoporous Carbon Cathode. Batteries & Supercaps, 5 (4): (e202100318). [PMID:] [10.1002/batt.202100318] |
| 3. Hui-Yuan Peng, Yuan-Hui Xiao, Huan-Huan Yu, Jia-Zheng Wang, Jian-De Lin, Rajkumar Devasenathipathy, Jia Liu, Pei-Hang Zou, Meng Zhang, Jian-Zhang Zhou, De-Yin Wu, Zhong-Qun Tian. (2021) Electrochemical and Plasmonic Photochemical Oxidation Processes of para-Aminothiophenol on a Nanostructured Gold Electrode. Journal of Physical Chemistry C, [PMID:] [10.1021/acs.jpcc.1c05928] |
| 4. Chao Hu, Huimin Qi, Jingfu Song, Gai Zhao, Jiaxin Yu, Yafeng Zhang, Hongtu He, Jianping Lai. (2021) Exploration on the tribological mechanisms of polyimide with different molecular structures in different temperatures. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2021.150051] |
| 5. Huadong Zhang, Huasheng Lai, Xiangrong Wu, Gongke Li, Yufei Hu. (2020) CoFe2O4@HNTs/AuNPs Substrate for Rapid Magnetic Solid-Phase Extraction and Efficient SERS Detection of Complex Samples All-in-One. ANALYTICAL CHEMISTRY, [PMID:32069032] [10.1021/acs.analchem.0c00144] |
| 6. Ma Yankai, Nie Bei. (2019) Unraveling a self-assembling mechanism of isomeric aminothiophenol on Ag dendrite by correlated SERS and matrix-free LDI-MS. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 411 (30): (8081-8089). [PMID:31754768] [10.1007/s00216-019-02187-1] |
| 7. Qianhui Xia, Lianmin Chen, Ye Zhu, Zengwu Shao, Mingyu Guo. (2018) Stretchy and strong polyurethane–urea supramolecular (PUUS) hydrogels with various stimulus-responsive behaviours: the effect of chain-extenders. Journal of Materials Chemistry B, 7 (10): (1734-1740). [PMID:32254915] [10.1039/C8TB02585A] |
| 8. Yao Zhang, Mo Zhang, Xiaoxiao Hu, Han Hao, Cuilu Quan, Tiantian Ren, Huile Gao, Jing Wang. (2024) Engineering a porphyrin COFs encapsulated by hyaluronic acid tumor-targeted nanoplatform for sequential chemo-photodynamic multimodal tumor therapy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39242006] [10.1016/j.ijbiomac.2024.135328] |
| 9. Meiting Li, Zhuoyin Liu, Junjie Tang, LiLi Cheng, Yifan Xue, Yadong Liu, Jie Liu. (2024) Facile Synthesis of a Multifunctional Porous Organic Polymer Nanosonosensitizer (mHM@HMME) for Enhanced Cancer Sonodynamic Therapy. ACS Applied Materials & Interfaces, [PMID:38769350] [10.1021/acsami.4c02651] |
| 10. Yanna Zhao, Yingying Zhang, Xiaowei Bai, Yuqi Wang, Yiqing Li, Shuai Yang. (2024) Sustainable poly(imide-imide) vitrimer based on multiple dynamic covalent bonds. JOURNAL OF APPLIED POLYMER SCIENCE, 141 (48): (e56281). [PMID:] [10.1002/app.56281] |
| 11. Jie Chen, Wen Zeng, Huiyao Huang, Xiaoyu Lou, Song Chen, Changshen Ye, Zhixian Huang, Ting Qiu. (2025) Tunable porosity and Hg (II) adsorption performance in dual heteroatom functionalized conjugated micro-mesoporous poly(aniline)s. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2025.131997] |
| 12. Feng Wang, Zequan Shen, Hui Wang, Yuheng Zhang, Baoxia Dong, Defeng Wu. (2026) Solar-driven dye wastewater purification and synergistic desalination by an aerogel-based multitasking platform structured with polydopamine-hybridized covalent organic frameworks. JOURNAL OF HAZARDOUS MATERIALS, [PMID:] [10.1016/j.jhazmat.2026.141809] |
