4-Hydroxy Isoleucine - ≥95% , CAS No.781658-23-9

CAS: 781658-23-9 Cat. No.: H134438 Peso molecular: 147.17 Número EC: 631-182-5

GRADE & PURITY ≥95%

Synonyms

4-?Hydroxy-?L-?isoleucine | 4-HYDROXY-L-ISOLEUCINE | (2S,3R)-2-amino-4-hydroxy-3-methylpentanoic acid | CCG-266183 | 4-ydroxy--soleucine | 4-Hydroxyisoleucine, United States Pharmacopeia (USP) Reference Standard | Rel-(2S,3R)-2-amino-4-hydroxy-3-methylpen

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

4-?Hydroxy-?L-?isoleucine | 4-HYDROXY-L-ISOLEUCINE | (2S, 3R)-2-amino-4-hydroxy-3-methylpentanoic acid | CCG-266183 | 4-ydroxy--soleucine | 4-Hydroxyisoleucine, United States Pharmacopeia (USP) Reference Standard | Rel-(2S, 3R)-2-amino-4-hydroxy-3-methylpen

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

A special amino acid extracted from the seeds of fenugreek, which has never been found in mammalian tissues, shows proinsulin activity; Effects on insulin secretion, plant-based treatment of metabolic syndrome.

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 488193530
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488193530
• Sonrisas canónicas: CC(C(C)O)C(C(=O)O)N
• IUPAC Name: (2S,3R)-2-amino-4-hydroxy-3-methylpentanoic acid
• InChIKey: OSCCDBFHNMXNME-DSDZBIDZSA-N
• INCHI: 1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4?,5-/m0/s1
• Isómeros SMILES: C[C@H]([C@@H](C(=O)O)N)C(C)O
• WGK Alemania: 3
• Peso molecular: 147.17
• Reaxy-Rn: 11036006
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11036006&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Isoleucine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Isoleucine and derivatives
• Alternative Parents: L-alpha-amino acids Short-chain hydroxy acids and derivatives Methyl-branched fatty acids Hydroxy fatty acids 1,3-aminoalcohols Secondary alcohols Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Isoleucine or derivatives - Alpha-amino acid - L-alpha-amino acid - Branched fatty acid - Hydroxy fatty acid - Methyl-branched fatty acid - Short-chain hydroxy acid - Fatty acyl - Fatty acid - 1,3-aminoalcohol - Amino acid - Secondary alcohol - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Primary amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Amine - Organic oxygen compound - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as isoleucine and derivatives. These are compounds containing isoleucine or a derivative thereof resulting from reaction of isoleucine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: soluble in water
• Punto de inflamación (°F): 296.6 °F
• Punto de inflamación (°C): 147 °C
• Peso molecular: 147.170 g/mol
• XLogP3: -2.800
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 147.09 Da
• Monoisotopic Mass: 147.09 Da
• Topological Polar Surface Area: 83.600 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 126.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Emmanuel Osei Nkansah, Yunzhu Lan, Hui Zhang, Binbin Xu, Qiaodan Li, Mohammad Ishraq Zafar, Jian Xu.  (2025)  Potential role of 4-hydroxyisoleucine in enhancing fertility in male mice with diet-induced obesity.  Frontiers in Endocrinology,      [PMID:40917356] [10.3389/fendo.2025.1561543]