Melting point standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Melting point standard 182-184 °C, p-anisic acid is useful for the regular assessment of identity or purity of a substance. Its value is determined as an average of 6 to 12 measurements with a Büchi B-545 instrument that is calibrated against primary standards.
Application：
This product is an analytical standard used as a melting point calibration standard.
Features and advantages：
Melting point standardized in the thermodynamic mode of analysis
Standard deviation up to ± 0.3 °C
Documented with certificates of analysis and safety data sheet
| Pubchem Sid | 504751357 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504751357 |
| Sonrisas canónicas | COC1=CC=C(C=C1)C(=O)O |
| IUPAC Name | 4-methoxybenzoic acid |
| InChIKey | ZEYHEAKUIGZSGI-UHFFFAOYSA-N |
| INCHI | 1S/C8H8O3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H,9,10) |
| Isómeros SMILES | COC1=CC=C(C=C1)C(=O)O |
| WGK Alemania | 1 |
| RTECS | BZ4395000 |
| Peso molecular | 152.15 |
| Beilstein | 508910 |
| Reaxy-Rn | 508910 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=508910&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Benzoic acids and derivatives |
| Intermediate Tree Nodes | Methoxybenzoic acids and derivatives |
| Direct Parent | P-methoxybenzoic acids and derivatives |
| Alternative Parents | Benzoic acids Phenoxy compounds Methoxybenzenes Benzoyl derivatives Anisoles Alkyl aryl ethers Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | P-methoxybenzoic acid or derivatives - Benzoic acid - Anisole - Phenoxy compound - Benzoyl - Phenol ether - Methoxybenzene - Alkyl aryl ether - Monocarboxylic acid or derivatives - Ether - Carboxylic acid - Carboxylic acid derivative - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as p-methoxybenzoic acids and derivatives. These are benzoic acids in which the hydrogen atom at position 4 of the benzene ring is replaced by a methoxy group. |
| External Descriptors | methoxybenzoic acid |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 F2415180 | Certificate of Analysis | Mar 18, 2026 | M119543 |
| I2021109 | Certificate of Analysis | Feb 05, 2026 | M119543 |
| D2417389 | Certificate of Analysis | Feb 05, 2026 | M119543 |
| C2517536 | Certificate of Analysis | Mar 25, 2025 | M119543 |
| C2517537 | Certificate of Analysis | Mar 25, 2025 | M119543 |
| F2415164 | Certificate of Analysis | Jun 18, 2024 | M119543 |
| F2415189 | Certificate of Analysis | Jun 18, 2024 | M119543 |
| D2422459 | Certificate of Analysis | Apr 23, 2024 | M119543 |
| J2211488 | Certificate of Analysis | Oct 17, 2022 | M119543 |
| I2021108 | Certificate of Analysis | Aug 05, 2022 | M119543 |
| Punto de inflamación (°C) | 185℃ |
|---|---|
| Punto de ebullición (°C) | 275-280°C |
| Punto de fusión (°C) | 184°C |
| Peso molecular | 152.150 g/mol |
| XLogP3 | 2.000 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 152.047 Da |
| Monoisotopic Mass | 152.047 Da |
| Topological Polar Surface Area | 46.500 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 136.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Yingying Liu, Xue Wang, Danyang Zhang, Chen Wang, Haijiao Xie, Hongping Chen, Yunfeng Chai. (2023) Does deprotonated benzoic acid lose carbon monoxide in collision-induced dissociation?. JOURNAL OF MASS SPECTROMETRY, 59 (1): (e4990). [PMID:38146124] [10.1002/jms.4990] |
| 2. Yunfeng Ma, Longxia Li, Liufang Mo, Xiaochen Wang, Chenyue Liu, Yijun Wu, Chaoqun Liu. (2023) Preparation and anti-tumor effects of mesoporous silica nanoparticles loaded with trifluoperazine. Journal of Materials Chemistry B, 11 (43): (10395-10403). [PMID:37876312] [10.1039/D3TB01472J] |
| 3. Meng Liu, Zhe-Yong Chen, Xiao-Hang He, Xing-Yu Liu, Hui-Ling Hu, Huan Tian, Yi Liu, Feng-Lei Jiang. (2023) Thermodynamics of Ligand Exchange with Aromatic Ligands on the Surface of CdSe Quantum Dots. CHEMISTRY OF MATERIALS, [PMID:] [10.1021/acs.chemmater.2c02651] |
| 4. Yue Zhou, Lei Xu, Zhangding Wang, Hongwen Liu, Xiang Zhang, Chuanjun Shu, Meng Zhang, Ting Wang, Xinyun Xu, Xiaohong Pu, Jian He, Pin Wang, Yudong Qiu, Guifang Xu, Xiaoping Zou, Yun Zhu, Lei Wang. (2022) Sequentially targeting and intervening mutual Polo-like Kinase 1 on CAFs and tumor cells by dual targeting nano-platform for cholangiocarcinoma treatment. Theranostics, [PMID:35664077] [10.7150/thno.70557] |
| 5. Jieqiong Lv, Runcheng Liang, Zihua Xia, Yong Li, Zhufen Lv, Dongzhi Hou, Liping Yu, Gang Chen, Yi Liu, Fan Yang. (2019) Synthesis and characterization of amphiphilic star-shaped copolymers based on β-cyclodextrin for micelles drug delivery. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, [PMID:30922119] [10.1080/03639045.2019.1593437] |
| 6. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang. (2018) Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & Function, 9 (9): (4858-4864). [PMID:30156246] [10.1039/C8FO00609A] |
| 7. Hongyue Guo, Renhua Liu, Jinjin Yang, Bingcheng Yang, Xinmiao Liang, Changhu Chu. (2011) A novel click lysine zwitterionic stationary phase for hydrophilic interaction liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, [PMID:22226552] [10.1016/j.chroma.2011.12.033] |
| 8. Jinwei Tian, Yao Wei, Chengwei Lü. (2025) 1,3,4-Thiadiazole and quinolinone based multifunctional probes for fluorescence turn-on and colorimetric monitoring of Al3+ and Fe3+ in food and aqueous environment applications. FOOD CHEMISTRY, [PMID:41485311] [10.1016/j.foodchem.2025.147792] |
