Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 32 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
4-Pyridinecarboxaldehyde is a heterocyclic building block used to prepare Schiff bases via a Korich-type reaction.
| Sonrisas canónicas | C1=CN=CC=C1C=O |
|---|---|
| IUPAC Name | pyridine-4-carbaldehyde |
| InChIKey | BGUWFUQJCDRPTL-UHFFFAOYSA-N |
| INCHI | 1S/C6H5NO/c8-5-6-1-3-7-4-2-6/h1-5H |
| Isómeros SMILES | C1=CN=CC=C1C=O |
| WGK Alemania | 1 |
| RTECS | NR9400000 |
| Número ONU | 1993 |
| Peso molecular | 107.11 |
| Beilstein | 105342 |
| Reaxy-Rn | 105342 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=105342&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Pyridines and derivatives |
| Subclass | Pyridine carboxaldehydes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Pyridine carboxaldehydes |
| Alternative Parents | Aryl-aldehydes Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | 4-pyridine carboxaldehyde - Aryl-aldehyde - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aldehyde - Aromatic heteromonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as pyridine carboxaldehydes. These are aromatic compounds containing a pyridine ring which bears a carboxaldehyde group. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Mar 06, 2026 | P105913 | |
| Certificate of Analysis | Mar 06, 2026 | P105913 | |
| Certificate of Analysis | Mar 06, 2026 | P105913 | |
| Certificate of Analysis | Mar 06, 2026 | P105913 | |
| Certificate of Analysis | Feb 04, 2026 | P105913 | |
| Certificate of Analysis | Feb 04, 2026 | P105913 | |
| Certificate of Analysis | Jan 19, 2026 | P105913 | |
| Certificate of Analysis | Jan 07, 2025 | P105913 | |
| Certificate of Analysis | Jan 07, 2025 | P105913 | |
| Certificate of Analysis | Jan 07, 2025 | P105913 | |
| Certificate of Analysis | Jan 07, 2025 | P105913 | |
| Certificate of Analysis | Jan 07, 2025 | P105913 | |
| Certificate of Analysis | Jan 07, 2025 | P105913 | |
| Certificate of Analysis | May 20, 2024 | P105913 | |
| Certificate of Analysis | Feb 29, 2024 | P105913 | |
| Certificate of Analysis | Apr 11, 2023 | P105913 | |
| Certificate of Analysis | Apr 11, 2023 | P105913 | |
| Certificate of Analysis | Apr 11, 2023 | P105913 | |
| Certificate of Analysis | Apr 11, 2023 | P105913 | |
| Certificate of Analysis | Apr 11, 2023 | P105913 | |
| Certificate of Analysis | Jun 30, 2022 | P105913 | |
| Certificate of Analysis | Jun 30, 2022 | P105913 | |
| Certificate of Analysis | Jun 21, 2022 | P105913 | |
| Certificate of Analysis | Feb 21, 2022 | P105913 |
| Solubilidad | Soluble in water (20 mg/ml at 20 °C), ethanol, and acetone. |
|---|---|
| Sensibilidad | Air and Light sensitive. |
| Índice de refracción | 1.5352 |
| Punto de inflamación (°F) | 179.6 °F |
| Punto de inflamación (°C) | 54℃ |
| Punto de ebullición (°C) | 198°C |
| Punto de fusión (°C) | -2--4°C |
| Peso molecular | 107.110 g/mol |
| XLogP3 | 0.400 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 107.037 Da |
| Monoisotopic Mass | 107.037 Da |
| Topological Polar Surface Area | 30.000 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 76.600 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Ziming Qiao, Zhipeng Yang, Mengke Li, Yi Feng, Xiongwei Qu, Hemi Qu, Xiaojie Zhang. (2023) One-Pot Synthesis of Quaternary Pyridinium-Type Cationic-Based Porous Organic Frameworks: Enhanced Poly(ethylene oxide) Composite Polymer Electrolytes for All-Solid-State Li–S Batteries. ACS Applied Energy Materials, [PMID:] [10.1021/acsaem.3c02630] |
| 2. Brian Musikavanhu, Zeping Huang, Quanhong Ma, Yongdi Liang, Zhaoli Xue, Lei Feng, Long Zhao. (2023) A pyridine modified naphthol hydrazone Schiff base chemosensor for Al3+ via intramolecular charge transfer process. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:37290147] [10.1016/j.saa.2023.122961] |
| 3. Yajuan Wang, Wenqiang Liu, Jiangxin Li, Juan Zhang. (2022) Preparation of porous macromolecule oxazine poly-ionic liquid solid acid catalyst and its application in an esterification reaction. JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 98 (1): (129-139). [PMID:] [10.1002/jctb.7228] |
| 4. Zheng Qu, Jiamin Huang, Guoliang Wu, Liangliang Dong, Chunfang Zhang, Yunxiang Bai. (2022) Tailor-made iron-organic molecular cage embedded polydimethylsiloxane membranes via emulsion casting technique for efficient VOCs removal. JOURNAL OF APPLIED POLYMER SCIENCE, 139 (41): (e53004). [PMID:] [10.1002/app.53004] |
| 5. Yupeng Chen, Chong Chen, Xue Li, Nengjie Feng, Lei Wang, Hui Wan, Guofeng Guan. (2022) Hydroxyl-ionic liquid functionalized metalloporphyrin as an efficient heterogeneous catalyst for cooperative cycloaddition of CO2 with epoxides. Journal of CO2 Utilization, [PMID:] [10.1016/j.jcou.2022.102107] |
| 6. Yuhao Chen, Zhonghua Chen, Yaowen Zhuo. (2022) Newly Synthesized Morpholinyl Mannich Bases as Corrosion Inhibitors for N80 Steel in Acid Environment. Materials, 15 (12): (4218). [PMID:35744277] [10.3390/ma15124218] |
| 7. Boyi Chen, Zhongyuan Wang, Junsen Wang, Hailing Zheng, Junyi Zhou, Xushi Chen, Bing Wang, Yang Zhou, Zhiqin Peng. (2021) Ultrasensitive dual enhanced electrochemical immunosensor to detect ancient wool relics. Analytical Methods, 14 (4): (394-400). [PMID:34981794] [10.1039/D1AY01514A] |
| 8. Xin Lai, Jianfeng Hu, Tao Ruan, Jianhui Zhou, Jinqing Qu. (2021) Chitosan derivative corrosion inhibitor for aluminum alloy in sodium chloride solution: A green organic/inorganic hybrid. CARBOHYDRATE POLYMERS, [PMID:33966838] [10.1016/j.carbpol.2021.118074] |
| 9. Yue Zhang, Lin Liu, Wei-Guo Xu, Zheng-Bo Han. (2021) MOF@POP core–shell architecture as synergetic catalyst for high-efficient CO2 fixation without cocatalyst under mild conditions. Journal of CO2 Utilization, [PMID:] [10.1016/j.jcou.2021.101463] |
| 10. Hengye Chen, Liuna Wei, Xiaoming Guo, Chengying Hai, Lu Xu, Lei Zhang, Wei Lan, Chunsong Zhou, Yuanbin She, Haiyan Fu. (2020) Determination of l-theanine in tea water using fluorescence-visualized paper-based sensors based on CdTe quantum dots/corn carbon dots and nano-porphyrin with chemometrics. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 101 (6): (2552-2560). [PMID:33063338] [10.1002/jsfa.10882] |
| 11. Shichao Xu, Xiaojing Zeng, Songlin Dai, Jing Wang, Yuxiang Chen, Jie Song, Yunfei Shi, Xian Cheng, Shengliang Liao, Zhendong Zhao. (2020) Turpentine Derived Secondary Amines for Sustainable Crop Protection: Synthesis, Activity Evaluation and QSAR Study. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:32975941] [10.1021/acs.jafc.0c01909] |
| 12. Song Liu, Zhen-jie Huang, Feng Li, Wei-jing Zhang, Chun-rong Zhu, Cheng-bin Gong, Jun-fei Long, Qian Tang. (2020) Star-shaped monosubstituted 2,6-diphenyl-4,4′-bipyridinium salts with good electrochromic switching stability. SYNTHETIC METALS, [PMID:] [10.1016/j.synthmet.2020.116330] |
| 13. Dongmei He, Li Zeng, Guiqing Zhang, Wenjuan Guan, Zuoying Cao, Qinggang Li, Shengxi Wu. (2019) Extraction behavior and mechanism of nickel in chloride solution using a cleaner extractant. Journal of Cleaner Production, [PMID:] [10.1016/j.jclepro.2019.118517] |
| 14. Xu Han, Jilin Wang, Lulu Wang. (2018) Preparation of anion exchange membranes based on pyridine functionalized poly(vinyl alcohol) crosslinked by 1,4-dichlorobutane. JOURNAL OF APPLIED POLYMER SCIENCE, 136 (16): (47395). [PMID:] [10.1002/app.47395] |
| 15. Chunfang Zhang, Xuejian Si, Shuo Zhang, Bei Pei, Jin Gu, Yunxiang Bai. (2018) Porous metal–organic molecular cage: a promising candidate to highly improve the nanofiltration performance of thin film nanocomposite membranes. NEW JOURNAL OF CHEMISTRY, 43 (4): (1699-1709). [PMID:] [10.1039/C8NJ04603D] |
| 16. Tingting Xiao, Xiaoyang Zhang, Jingyu Wu, Jiazhi Yang, Yong Yang. (2017) Aliphatic-Alcohol-Induced Opaque-to-Transparent Transformation and Application of Solubility Theory in a Bis-Dipeptide-Based Supramolecular Gel. ChemPlusChem, 82 (6): (879-887). [PMID:31961561] [10.1002/cplu.201700206] |
| 17. He Li, Chunzhi Li, Jian Chen, Lina Liu, Qihua Yang. (2017) Synthesis of a Pyridine–Zinc-Based Porous Organic Polymer for the Co-catalyst-Free Cycloaddition of Epoxides. Chemistry-An Asian Journal, 12 (10): (1095-1103). [PMID:28326679] [10.1002/asia.201700258] |
| 18. Xiuquan Jia, Jiping Ma, Min Wang, Xiaofang Li, Jin Gao, Jie Xu. (2016) Alkali α-MnO2/NaxMnO2 collaboratively catalyzed ammoxidation–Pinner tandem reaction of aldehydes. Catalysis Science & Technology, 6 (20): (7429-7436). [PMID:] [10.1039/C6CY00874G] |
| 19. Weifen Niu, Ming Nan, Li Fan, Man Shing Wong, Shaomin Shuang, Chuan Dong. (2015) A novel pH fluorescent probe based on indocyanine for imaging of living cells. DYES AND PIGMENTS, [PMID:] [10.1016/j.dyepig.2015.11.027] |
| 20. Gang Liu, Mingdi Yang, Lianke Wang, Jun Zheng, Hongping Zhou, Jieying Wu, Yupeng Tian. (2014) Schiff base derivatives containing heterocycles with aggregation-induced emission and recognition ability. Journal of Materials Chemistry C, 2 (15): (2684-2691). [PMID:] [10.1039/C3TC32591A] |
| 21. Xuan Kuang, Yu Ma, Hao Su, Jine Zhang, Yu-Bin Dong, Bo Tang. (2014) High-Performance Liquid Chromatographic Enantioseparation of Racemic Drugs Based on Homochiral Metal–Organic Framework. ANALYTICAL CHEMISTRY, [PMID:24380495] [10.1021/ac403674p] |
| 22. Xuewu Gao, Zhipeng Yang, Mengke Li, Haifeng Ji, Xinyang Liu, Zan Zhang, Shengli Chen, Yi Feng, Yu Jiang, Xiaojie Zhang. (2024) A novel phosphorus-containing pyridinium porous organic framework with flame retardancy for enhancing efficiency and safety of solid-state polymer electrolyte. JOURNAL OF POWER SOURCES, [PMID:] [10.1016/j.jpowsour.2024.235639] |
| 23. Guo Jun, Duan Yulong, Jia Yunling, Zhao Zelong, Gao Xiaoqing, Liu Pai, Li Fangfang, Chen Hongli, Ye Yutong, Liu Yujiao, Zhao Meiting, Tang Zhiyong, Liu Yi. (2024) Biomimetic chiral hydrogen-bonded organic-inorganic frameworks. Nature Communications, 15 (1): (1-11). [PMID:38167785] [10.1038/s41467-023-43700-6] |
| 24. Zixu Xie, Zhiran Zheng, Chen Chen, Guofeng Li, Xing Wang. (2024) Borneol-Modified Chitosan Coating with Antibacterial Properties via Layer-by-Layer Strategy. Coatings, 14 (4): (381). [PMID:] [10.3390/coatings14040381] |
| 25. Guiyuan Yang, Fangyuan Hu, Li-Li Cui, Meihong Fan, Xin Ge, Xingquan He, Wei Zhang, Tewodros Asefa. (2024) Deriving paired Fe sites on N-doped carbon from Fe(III)-tetrapyridinylporphyrin-modified ZIF-8: robust electrocatalysts for air electrodes in zinc–air batteries. Inorganic Chemistry Frontiers, [PMID:] [10.1039/D3QI02524A] |
| 26. Miantuo Li, Fengting Li, Jianwen Hu, Nannan Cui, Huiling Su, Lizhi Li, Zhikun Wang, Shuangqing Sun, Songqing Hu. (2024) Preparation and corrosion inhibition mechanism of a chitosan ionic liquid Schiff base for the protection of N80 in HCl solution. NEW JOURNAL OF CHEMISTRY, 48 (7): (3064-3079). [PMID:] [10.1039/D3NJ05103J] |
| 27. Shuangjiang Li, Yi Liu, Li Lin, Manoj Pudukudy, Churu Zhang, Wenbo Zhao, Tianding Hu, Ziqiong Hui, Yunfei Zhi, Shaoyun Shan. (2024) Synergistic effects of multiple functionalities in a modified triazine-based organic polymer for enhanced CO2 cycloaddition with epoxides. FUEL, [PMID:] [10.1016/j.fuel.2024.134057] |
| 28. Ji Yongli, Yang Caoyu, Ye Yutong, Zhang Yin, Zhao Tingting, Kong Shuyue, Chen Hongli, Liu Pai, Zhao Zelong, Li Yilong, Li Jing, Ma Ruixiao, Ban Zhiyong, Yuan Kuo, Tang Zhiyong, Liu Yi, Zhao Meiting, Guo Jun. (2025) Disassembly of chiral hydrogen-bonded frameworks into single-unit organometallic helices for enantioselective amyloid inhibition. Nature Communications, 16 (1): (1-15). [PMID:40866394] [10.1038/s41467-025-63459-2] |
| 29. Deming Zhou, Chenji Zhang, Leyan Li, Lifan Li, Jiapeng Ye, Kun Luan, Zaixing Zhang, Lingxiao Jing, Ruizhi Xue, Tonghua Zhang. (2025) Grafting quaternary ammonium onto polyvinyl alcohol for imparting durable antibacterial, flame-retardant, and recyclable anion-absorptive properties. POLYMER, [PMID:] [10.1016/j.polymer.2025.128939] |
| 30. Lifan Li, Deming Zhou, Jiapeng Ye, Kun Luan, Zaixing Zhang, Lingxiao Jing, Tonghua Zhang. (2025) Long-lasting antibacterial cotton fabric treated with “one-bath” impregnation of N-halamine precursor. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.162290] |
| 31. Yan Zhang, Xiaolong Xie, Song Zhao, Rui Jiang, Wenjing Qi, Lianzhe Hu. (2025) Detection of dissolved Ammonia and trinitrophenol using hydrogel tags doped with pyridine-functionalized AIEgens: A strategy for mitigating ammonium picrate hazards in explosive disposal. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:41412042] [10.1016/j.saa.2025.127345] |
| 32. Shaojie Chen, Hao Tang, Xiaoliang Fan, Bohan Li, Yaomin Wang, Wei Zhou, Xiaoyu Jiang, Xiaomin Dong, Yanyi Wang, Peng Zhao, Tianwen Ye, Bolin An, Yijun Zheng, Chao Zhong. (2026) Bio-orthogonal functionalization of bacterial cellulose combining metabolic glycoengineering and click chemistry. Nature Communications, [PMID:41633993] [10.1038/s41467-026-69130-8] |