5,10,15,20-Tetrakis(4-aminophenyl)porphyrin - ≥95% , CAS No.22112-84-1

CAS: 22112-84-1 Cat. No.: T123122 Peso molecular: 674.81 Número EC: 678-632-7 PubChem CID: 135411734

GRADE & PURITY ≥95%

Synonyms

4-[10,15,20-tris(4-aminophenyl)-21,23-dihydroporphyrin-5-yl]aniline | TPAPP | 5,10,15,20-Tetrakis(4-aminophenyl)porphyrin | YSZC137 | Tetra(p-aminophenyl)porphyrin | 5,10,15,20-Tetrakis(4-aminophenyl)-21H,23H-porphine | Tetra-(4-aminophenyl)porphine

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

Descripción general

5,10,15,20-Tetrakis(4-aminophenyl)porphyrin is porphyrin compound that is substituted with four 4-aminophenyl moieties. This porphyrin has been described as a useful ligand for the design of catalysts, and was used to prepare a manganese (III) complex for catalyzing oxidative decarboxylations of carboxylic acids with sodium periodate.
A 4-aminophenyl substituted porphyrin.

Specifications

Sinónimos

4-[10, 15, 20-tris(4-aminophenyl)-21, 23-dihydroporphyrin-5-yl]aniline | TPAPP | 5, 10, 15, 20-Tetrakis(4-aminophenyl)porphyrin | YSZC137 | Tetra(p-aminophenyl)porphyrin | 5, 10, 15, 20-Tetrakis(4-aminophenyl)-21H, 23H-porphine | Tetra-(4-aminophenyl)porphine

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Protected from light, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥95%

Nombres e identificadores

• Sonrisas canónicas: C1=CC(=CC=C1C2=C3C=CC(=C(C4=NC(=C(C5=CC=C(N5)C(=C6C=CC2=N6)C7=CC=C(C=C7)N)C8=CC=C(C=C8)N)C=C4)C9=CC=C(C=C9)N)N3)N
• IUPAC Name: 4-[10,15,20-tris(4-aminophenyl)-21,23-dihydroporphyrin-5-yl]aniline
• InChIKey: REPFNYFEIOZRLM-UHFFFAOYSA-N
• INCHI: 1S/C44H34N8/c45-29-9-1-25(2-10-29)41-33-17-19-35(49-33)42(26-3-11-30(46)12-4-26)37-21-23-39(51-37)44(28-7-15-32(48)16-8-28)40-24-22-38(52-40)43(36-20-18-34(41)50-36)27-5-13-31(47)14-6-27/h1-24,49,52H,45-48H2
• Isómeros SMILES: C1=CC(=CC=C1C2=C3C=CC(=C(C4=NC(=C(C5=CC=C(N5)C(=C6C=CC2=N6)C7=CC=C(C=C7)N)C8=CC=C(C=C8)N)C=C4)C9=CC=C(C=C9)N)N3)N
• PubChem CID: 135411734
• Peso molecular: 674.81
• Reaxy-Rn: 3643149

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Tetrapyrroles and derivatives
      • Subclass Porphyrins

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Tetrapyrroles and derivatives
• Subclass: Porphyrins
• Intermediate Tree Nodes: Not available
• Direct Parent: Porphyrins
• Alternative Parents: Aniline and substituted anilines Pyrroles Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Porphyrin - Aniline or substituted anilines - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Pyrrole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Pseudomonas aeruginosa (123386 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Light sensitive；Hygroscopic
• Peso molecular: 674.800 g/mol
• XLogP3: 7.700
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 674.291 Da
• Monoisotopic Mass: 674.291 Da
• Topological Polar Surface Area: 161.000 Ų
• Heavy Atom Count: 52
• Formal Charge: 0
• Complexity: 965.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Zou Bin, Liu Feng, Feng Ting, Yan Lishi, Suo Hongbo.  (2022)  A novel sensor based on metalloporphyrins-embedded covalent organic frameworks for rapid detection of antioxidants in plant oil.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2022.133227]

2. Huan Lin, Xin Cheng, Ming-Jie Yin, Zhouzhou Bao, Xunbin Wei, Bobo Gu.  (2020)  Flexible porphyrin doped polymer optical fibers for rapid and remote detection of trace DNT vapor.  ANALYST,  145  (15): (5307-5313).  [PMID:32555787] [10.1039/D0AN00706D]

3. Yi Hao, Xingyan Wang, Kaili Wang, Sijie Zhang, Long Zhang, Wenhao Liu, Xueyi Liu, Ruixia Gao, Sicen Wang, Jingang An.  (2025)  Enhanced chemodynamic porphyrin-modified magnetite nanoagents: A triple-action strategy for potent antimicrobial therapy and wound healing.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:39983401] [10.1016/j.jcis.2025.02.068]

4. Haiyan Zhao, Yi Zhou, Shanshan Li, Kemei Shi, Na Li, Min Cui, Cong Zhang.  (2024)  Fe-pCOFs/MoS2-MWCNTs nanocomposite with enzyme-like activity for efficient electrochemical detection of hydrogen peroxide from living cells.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.112590]

5. Xiaoyu Wang, Chunzhe Xu, Hantao Tian, Yu Pang, Jie Lv, Meng Li.  (2025)  FeS embedded bioreactor collaborate with artesunate for cascade-catalytic tumor ferroptosis.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40184656] [10.1016/j.jcis.2025.137479]

6. Jiaxin Li, Yanzhi Xing, Han Leng, Qi Han, Yanfeng Zhang, Jianhua Wang, Xuwei Chen.  (2025)  Hybrid cell membranes encapsulated MoS2 nanospheres as an efficient platform for synergetic PTT/PDT and real-time self-evaluation of therapeutic effect.  Applied Materials Today,      [PMID:] [10.1016/j.apmt.2025.102609]

7. Liu Qingju, Zhu Junyi, Wang Hui, Luan Yunxia, Zhang Zhikun.  (2024)  Porphyrin-based covalent organic framework as oxidase mimic for highly sensitive colorimetric detection of pesticides.  MICROCHIMICA ACTA,  191  (5): (1-11).  [PMID:38702534] [10.1007/s00604-024-06371-8]

8. Chen Yong-Jun, Xu Yi-Ming, Ye Xiao-Liang, Luo Zhi-Peng, Zhu Shi-Peng, Li Ke-Feng, Lu Jiang-Feng, Wang Guan-E, Xu Gang.  (2025)  Strategic energy-level modulation in porous heterojunctions: advancing gas sensing through Type-I to Type-II transitions.  Nature Communications,  16  (1): (1-10).  [PMID:40681497] [10.1038/s41467-025-61836-5]

9. Wenqian Zhu, Wenwen Cao, Rui Chen, Zhen Zhang, Chaohai Pang, Zhongsheng Yi, Shuhuai Li, Xionghui Ma, Jianping Li.  (2025)  A novel framework-targeted affinity-based sandwich photoelectrochemical sensor for trace acrylamide determination.  FOOD CHEMISTRY,      [PMID:40318334] [10.1016/j.foodchem.2025.144487]

10. Yueru Chen, Zongning Guo, Xuelin Huang, Jiangying Qu, Feng Gao, Kai Wan, You Zhang, Xiaofang Zhao, Zhe Jiao.  (2025)  Portable field detection device based on Por-COF-MF for the determination of SO2 in wine.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113961]

11. Zikang Chen, Jiajie Pan, Wenzhi Huang, Kaixiang Shi, Zihao Yang, Hao Wu, Suqing Wei, Guoxing Jiang, Wenwu Zou, Rui Zhang, Xu Li, Quanbing Liu.  (2025)  Heterogeneity-Segment Charge-Induced-Coupling Catalysis of Component-Selective-Type Covalent Organic Frameworks Interface toward Stabilizing Lithium Metal Anode.  ACS Nano,      [PMID:40130338] [10.1021/acsnano.4c18473]

12. Hongxin Zhao, Weichen Zhou, Sujiao Cao, Ruiqian Guo, Liqiang Zhou, Li Qiu.  (2025)  Dual-Enzymatic Nanocatalyst for Optimizing Hypoxia Wound Healing via Linkage-Enhanced Sonodynamic Antimicrobial Therapy.  Small,      [PMID:40545835] [10.1002/smll.202504524]

13. Peng Jiang, Yongnian Zeng, Wen Zhang, Jiapeng Lei, Xue Jiang, Wei Li.  (2025)  Three-in-one bilayer microneedle patch for ultrasound-activated antibacterial therapy and immune modulation in wound healing.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41177464] [10.1016/j.jconrel.2025.114375]

14. Chengcai He, Ye Zhang, Xiaozhen Liu, Chengmu Yu, Jie Lv, Yulong Lin, Lianmei Zhao, Meng Li.  (2025)  Self-amplifying hypoxia cascade in covalent organic framework/metal organic framework nanoreactors for synergistic cancer therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:41353990] [10.1016/j.jcis.2025.139602]

15. Xinhong Zhao, Yuanyuan Li, Yulong Ma, Wenxin Ji, Yonggang Sun.  (2026)  Preparation of a porphyrin-based COF functionalized silica-based material as an efficient solid-phase extraction adsorbent for enrichment and separation of bisphenol contaminants.  NEW JOURNAL OF CHEMISTRY,  50  (5): (2464-2477).  [PMID:] [10.1039/D5NJ04019A]