5'-AMP-Na2 - Moligand™, ≥99% , CAS No.4578-31-8

CAS: 4578-31-8 Cat. No.: A100357 Peso molecular: 391.18 Número EC: 224-961-2 PubChem CID: 20712

GRADE & PURITY Moligand™, ≥99%

Synonyms

Adenosine 5'-monophosphate disodium salt | UNII-T1WZ11DSRN | 5'-ADENYLIC ACID, SODIUM SALT (1:2) | AMP disodium salt | MFCD08689634 | Adenosine 5'-monophosphate, disodium salt | Adenosine 5'-monophosphoric acid disodium salt | A884311 | Disodium adenosine

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

Adenosine 5′-Monophosphate, Disodium Salt is a nucleotide that is widely distributed in nature. Adenosine 5′-Monophosphate, Disodium Salt is an activator of AMPK.
A nucleotide involved in the reactions of cellular energy transfers.

Specifications

Sinónimos

Adenosine 5'-monophosphate disodium salt | UNII-T1WZ11DSRN | 5'-ADENYLIC ACID, SODIUM SALT (1:2) | AMP disodium salt | MFCD08689634 | Adenosine 5'-monophosphate, disodium salt | Adenosine 5'-monophosphoric acid disodium salt | A884311 | Disodium adenosine

Especificaciones y pureza

Moligand™, ≥99%

Mecanismos bioquímicos y fisiológicos

Nucleotide involved in the reactions of cellular energy transfers. Acts as an activator of AMP-activated protein kinase (AMPK). Used as a substrate for enzymes such as AMP-thymidine kinase, AMP deaminase and 5'-nucleotidase.

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]
• IUPAC Name: disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
• InChIKey: QGXLVXZRPRRCRP-IDIVVRGQSA-L
• INCHI: 1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• Isómeros SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]
• CAS alternativo: 13474-03-8
• PubChem CID: 20712
• Peso molecular: 391.18

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleotides
      • Subclass Purine ribonucleotides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleotides
• Subclass: Purine ribonucleotides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine ribonucleoside monophosphates
• Alternative Parents: Pentose phosphates Glycosylamines 6-aminopurines Monosaccharide phosphates Aminopyrimidines and derivatives Alkyl phosphates Imidolactams N-substituted imidazoles Tetrahydrofurans Heteroaromatic compounds 1,2-diols Secondary alcohols Oxacyclic compounds Azacyclic compounds Organic oxides Hydrocarbon derivatives Primary amines Organic sodium salts Organic zwitterions Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine ribonucleoside monophosphate - Pentose-5-phosphate - Pentose phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Pentose monosaccharide - Monosaccharide phosphate - Imidazopyrimidine - Purine - Aminopyrimidine - Phosphoric acid ester - Monosaccharide - Pyrimidine - Alkyl phosphate - Organic phosphoric acid derivative - N-substituted imidazole - Imidolactam - Tetrahydrofuran - Heteroaromatic compound - Imidazole - Azole - Secondary alcohol - 1,2-diol - Oxacycle - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Organic salt - Amine - Organic sodium salt - Alcohol - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic zwitterion - Organonitrogen compound - Organooxygen compound - Primary amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine ribonucleoside monophosphates. These are nucleotides consisting of a purine base linked to a ribose to which one monophosphate group is attached.
• External Descriptors: organic molecular entity

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water (50 mg/ml), DMSO, and methanol.
• Sensibilidad: Air and moisture sensitive
• Rotación específica [α]: [α]20/D ?43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
• Punto de fusión (°C): 300 °C
• Peso molecular: 391.190 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 3
• Exact Mass: 391.027 Da
• Monoisotopic Mass: 391.027 Da
• Topological Polar Surface Area: 192.000 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 469.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Referencias

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