5'-Chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide - ≥98% , CAS No.92-72-8

CAS: 92-72-8 Cat. No.: C153732 Peso molecular: 357.79 Beilstein Registry Number: 13(4)2534 Número EC: 202-182-9

GRADE & PURITY ≥98%

Synonyms

Amanil Naphthol AS-ITR | C.I. Azoic Coupling Component 12 | Azotol O | 2-HYDROXY-N-(2,4-DIMETHOXY-5-CHLOROPHENYL)-3-NAPHTHAMIDE | 2-Naphthalenecarboxamide,4-dimethoxyphenyl)-3-hydroxy- | AKOS000115859 | Z56785457 | KIWA GROUNDER ITR | SB83660 | Naphtazol

Storage

Room temperature

Shipped In

Normal

Specifications

Sinónimos

Amanil Naphthol AS-ITR | C.I. Azoic Coupling Component 12 | Azotol O | 2-HYDROXY-N-(2, 4-DIMETHOXY-5-CHLOROPHENYL)-3-NAPHTHAMIDE | 2-Naphthalenecarboxamide, 4-dimethoxyphenyl)-3-hydroxy- | AKOS000115859 | Z56785457 | KIWA GROUNDER ITR | SB83660 | Naphtazol

Especificaciones y pureza

≥98%

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488183832
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488183832
• Sonrisas canónicas: COC1=CC(=C(C=C1NC(=O)C2=CC3=CC=CC=C3C=C2O)Cl)OC
• IUPAC Name: N-(5-chloro-2,4-dimethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide
• InChIKey: XDWATWCCUTYUDE-UHFFFAOYSA-N
• INCHI: 1S/C19H16ClNO4/c1-24-17-10-18(25-2)15(9-14(17)20)21-19(23)13-7-11-5-3-4-6-12(11)8-16(13)22/h3-10,22H,1-2H3,(H,21,23)
• Isómeros SMILES: COC1=CC(=C(C=C1NC(=O)C2=CC3=CC=CC=C3C=C2O)Cl)OC
• Peso molecular: 357.79
• Beilstein: 13(4)2534
• Reaxy-Rn: 1827656
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1827656&ln=

Objetivos asociados (humanos)

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEK293 (82097 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)

Discover Target: GNAS

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)

Discover Target: BRCA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

Discover Target: SMAD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

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TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

Discover Target: TARDBP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 Activities)

Discover Target: RAN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

vpr Aberrant vpr protein (14595 Activities)

Discover Target: vpr

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in Dimethylformamide
• Punto de fusión (°C): 200 °C
• Peso molecular: 357.800 g/mol
• XLogP3: 4.800
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 357.077 Da
• Monoisotopic Mass: 357.077 Da
• Topological Polar Surface Area: 67.800 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 463.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Qiong Jiang, Juanjuan Feng, Min Sun.  (2021)  Carbon fibers modified with carbon nanoparticles by a facile and fast flame preparation for in-tube solid-phase microextraction.  Arabian Journal of Chemistry,      [PMID:] [10.1016/j.arabjc.2021.103537]

2. Ziqi Liu, Xuan Tang, Feng Feng, Jing Xu, Can Wu, Guoru Dai, Wanqing Yue, Wenying Zhong, Keming Xu.  (2021)  Molecular design of peptide amphiphiles for controlled self-assembly and drug release.  Journal of Materials Chemistry B,  9  (15): (3326-3334).  [PMID:33881438] [10.1039/D1TB00173F]