5-Hydroxyindole - Moligand™, ≥98% , Allosteric modulator of 5-HT 3A, CAS No.1953-54-4, Allosteric modulator of 5-HT 3A

CAS: 1953-54-4 Cat. No.: H105520 Peso molecular: 133.15 Beilstein Registry Number: 112349 Número EC: 217-782-6
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
5-hydroxy indole | AC-5464 | DTXSID00173187 | EN300-79057 | Hydroxy-5 indole [French] | SCHEMBL50566 | H-6044 | AKOS005206937 | 1h-indole-5-ol | 1H-indol-5-ol. | 3fuh | UNII-320UN7XZYN | (R)-(+)-7-Methoxy2-aminotetralin | 5-21-03-00018 (Beilstein Handboo
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
250mg
H105520-250mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
9,90US$
1g
H105520-1g
3
11,90US$
5g
H105520-5g
3
39,90US$
10g
H105520-10g
3

65,90US$

98,90US$
Guardar 33,00 US$ (33.37%)
25g
H105520-25g
2

106,90US$

160,90US$
Guardar 54,00 US$ (33.56%)
100g
H105520-100g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
579,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Reactants for the preparation of antitumor agents (oximidazolyl / oxpyrimidinyl) benzenesulfonate and tubulin inhibitors

Reactants for preparation of o-aminobenzoic acid

It is used to prepare indole compounds as reactants of dopamine D2 receptor antagonists

Reactants for preparation of human β - adrenoceptor ligands containing naphthalimide or carbazole

Reactants for preparation of natural radiation protective agent melanin

Reactants for the preparation of 5-vinyl-3-pyridinonitrile, a PKC θ inhibitor

Specifications

Sinónimos
5-hydroxy indole | AC-5464 | DTXSID00173187 | EN300-79057 | Hydroxy-5 indole [French] | SCHEMBL50566 | H-6044 | AKOS005206937 | 1h-indole-5-ol | 1H-indol-5-ol. | 3fuh | UNII-320UN7XZYN | (R)-(+)-7-Methoxy2-aminotetralin | 5-21-03-00018 (Beilstein Handboo
Especificaciones y pureza
Moligand™, ≥98%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Protected from light, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
ALLOSTERIC MODULATOR
Mecanismo de acción
Allosteric modulator of 5-HT 3A
Pureza
≥98%
Nombres e identificadores
Pubchem Sid504752730
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504752730
Sonrisas canónicasC1=CC2=C(C=CN2)C=C1O
IUPAC Name1H-indol-5-ol
InChIKeyLMIQERWZRIFWNZ-UHFFFAOYSA-N
INCHI1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
Isómeros SMILES C1=CC2=C(C=CN2)C=C1O
WGK Alemania 3
RTECS NM2430000
Peso molecular 133.15
Beilstein 112349
Reaxy-Rn 112349
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=112349&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseIndoles and derivatives
SubclassHydroxyindoles
Intermediate Tree Nodes Not available
Direct ParentHydroxyindoles
Alternative Parents Indoles  1-hydroxy-2-unsubstituted benzenoids  Pyrroles  Heteroaromatic compounds  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Hydroxyindole - Indole - 1-hydroxy-2-unsubstituted benzenoid - Benzenoid - Heteroaromatic compound - Pyrrole - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as hydroxyindoles. These are organic compounds containing an indole moiety that carries a hydroxyl group.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
HTR3A Tclin 5-hydroxytryptamine receptor 3A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LTA4H Tchem Leukotriene A4 hydrolase (1442 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SULT2A1 Tbio Alcohol sulfotransferase (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP2 Tbio Ubiquitin carboxyl-terminal hydrolase 2 (8818 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SULT1A1 Tchem Sulfotransferase 1A1 (111 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAD51 Tchem DNA repair protein RAD51 homolog 1 (504 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
SULT1E1 Estrogen sulfotransferase (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
B16 (5829 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npsr1 Neuropeptide S receptor (260 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Blood (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Large T antigen (1457 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate TypeFechaArticulo
K2528344Certificate of AnalysisNov 14, 2025 H105520
K2528345Certificate of AnalysisNov 14, 2025 H105520
K2528346Certificate of AnalysisNov 14, 2025 H105520
K2528353Certificate of AnalysisNov 14, 2025 H105520
L2106544Certificate of AnalysisSep 09, 2025 H105520
A2507046Certificate of AnalysisJul 07, 2022 H105520
D2516118Certificate of AnalysisJul 07, 2022 H105520
I2219023Certificate of AnalysisJul 07, 2022 H105520
I2219024Certificate of AnalysisJul 07, 2022 H105520
I2219025Certificate of AnalysisJul 07, 2022 H105520
I2219026Certificate of AnalysisJul 07, 2022 H105520

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Propiedades químicas y físicas
SensibilidadAir sensitive ,Light sensitive
Punto de fusión (°C)107-110°C
Peso molecular133.150 g/mol
XLogP32.000
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass133.053 Da
Monoisotopic Mass133.053 Da
Topological Polar Surface Area36.000 Ų
Heavy Atom Count10
Formal Charge0
Complexity126.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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