ZnAF-1 (Zinc ion fluorescent probe) - BioReagent, for Microscopy, for Fluorescence analysis, Biological Stain, ≥95% , CAS No.321859-09-0

CAS: 321859-09-0 Cat. No.: I276200 Peso molecular: 572.61

GRADE & PURITY BioReagent, Biological Stain, for Fluorescence analysis, for Microscopy, ≥95%

Synonyms

ZnAF-1, >=95.0% (HPCE) | 5-[2-[bis(pyridin-2-ylmethyl)amino]ethylamino]-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid | ZnAF1;ZnAF 1 | J-100252 | ZnAF-1 | ZnAF-1,5-Iso | DTXSID90437725 | 5-{2-[Bis(2-pyridylmethyl)amino]ethylamino}fluorescein

Storage

Protected from light,Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Application

Cell Staining, Fluorescence Analysis

Descripción general

ZnAF-1 (Zinc ion fluorescent probe), a fluorescein-based zinc sensor containing the N,N-bis(2-pyridylmethyl)ethylenediamine chelating unit, can be used for Zn²⁺ detection . ZnAF-1 can bind Zn(II) with a 1:1 stoichiometry.

Specifications

Sinónimos

ZnAF-1, >=95.0% (HPCE) | 5-[2-[bis(pyridin-2-ylmethyl)amino]ethylamino]-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid | ZnAF1;ZnAF 1 | J-100252 | ZnAF-1 | ZnAF-1, 5-Iso | DTXSID90437725 | 5-{2-[Bis(2-pyridylmethyl)amino]ethylamino}fluorescein

Especificaciones y pureza

BioReagent, for Microscopy, for Fluorescence analysis, Biological Stain, ≥95%

Mecanismos bioquímicos y fisiológicos

Membrane-impermeable, ethylenediaminofluoresceinyl compound used as a high-affinity Zn 2+ -specific fluorescent probe.

Estabilidad y almacenamiento

Store at -20℃ long term (24 months). Store in the dark. Avoid freeze/thaw cycle.

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Avoid repeated freezing and thawing

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Biological Stain, BioReagent, for Fluorescence analysis, for Microscopy

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Sonrisas canónicas: C1=CC=NC(=C1)CN(CCNC2=CC(=C(C=C2)C3=C4C=CC(=O)C=C4OC5=C3C=CC(=C5)O)C(=O)O)CC6=CC=CC=N6
• IUPAC Name: 5-[2-[bis(pyridin-2-ylmethyl)amino]ethylamino]-2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
• InChIKey: SAVLVCGHDLKAAF-UHFFFAOYSA-N
• INCHI: 1S/C34H28N4O5/c39-25-8-11-28-31(18-25)43-32-19-26(40)9-12-29(32)33(28)27-10-7-22(17-30(27)34(41)42)37-15-16-38(20-23-5-1-3-13-35-23)21-24-6-2-4-14-36-24/h1-14,17-19,37,39H,15-16,20-21H2,(H,41,42)
• Isómeros SMILES: C1=CC=NC(=C1)CN(CCNC2=CC(=C(C=C2)C3=C4C=CC(=O)C=C4OC5=C3C=CC(=C5)O)C(=O)O)CC6=CC=CC=N6
• Peso molecular: 572.61
• Reaxy-Rn: 8885517
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8885517&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Benzopyrans
      • Subclass 1-benzopyrans
        • Level5 Dibenzopyrans
          • Level6 Xanthenes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Benzopyrans
• Subclass: 1-benzopyrans
• Intermediate Tree Nodes: Dibenzopyrans
• Direct Parent: Xanthenes
• Alternative Parents: Aminobenzoic acids Benzoic acids Phenylalkylamines 2-pyridylmethylamines Aniline and substituted anilines Benzoyl derivatives 1-hydroxy-2-unsubstituted benzenoids Secondary alkylarylamines Heteroaromatic compounds Trialkylamines Amino acids Cyclic ketones Monocarboxylic acids and derivatives Azacyclic compounds Carboxylic acids Oxacyclic compounds Organic oxides Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Xanthene - Aminobenzoic acid - Aminobenzoic acid or derivatives - Benzoic acid or derivatives - Benzoic acid - 2-pyridylmethylamine - Benzoyl - Phenylalkylamine - Aniline or substituted anilines - 1-hydroxy-2-unsubstituted benzenoid - Secondary aliphatic/aromatic amine - Aralkylamine - Monocyclic benzene moiety - Pyridine - Benzenoid - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Tertiary amine - Tertiary aliphatic amine - Cyclic ketone - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Azacycle - Secondary amine - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Amine - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO
• Sensibilidad: Light-sensitive; Moisture sensitive
• Peso molecular: 572.600 g/mol
• XLogP3: 1.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 10
• Exact Mass: 572.206 Da
• Monoisotopic Mass: 572.206 Da
• Topological Polar Surface Area: 125.000 Ų
• Heavy Atom Count: 43
• Formal Charge: 0
• Complexity: 1080.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1