6-tert-Butyl-2,3-naphthalenedicarbonitrile - ≥97% , CAS No.32703-82-5

CAS: 32703-82-5 Cat. No.: I169585 Peso molecular: 234.30 Número EC: 624-291-4

GRADE & PURITY ≥97%

Synonyms

BRD9876 | BRD-9876 | IDI1_031074 | HMS1522G08 | 6-(t-Butyl)naphthalene-2,3-dicarbonitrile | SW198832-2 | 6-t-butyl-2,3-dicyanonaphthalene | HY-110208 | 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile | DS-8564 | O11512 | NCGC00093669-01 | AMY38493 | 6

Storage

Protected from light,Room temperature

Shipped In

Normal

Descripción general

This product is a selective inhibitor of MM1S growth, which can lock kinesin 5 in a state that enhances microtubule binding, resulting in MT binding and stability. It specifically targets microtubule-bound Eg5, selectively inhibits myeloma of CD34 cells, and has research potential for multiple myeloma.

Specifications

Sinónimos

BRD9876 | BRD-9876 | IDI1_031074 | HMS1522G08 | 6-(t-Butyl)naphthalene-2, 3-dicarbonitrile | SW198832-2 | 6-t-butyl-2, 3-dicyanonaphthalene | HY-110208 | 6-(1, 1-Dimethylethyl)-2, 3-naphthalenedicarbonitrile | DS-8564 | O11512 | NCGC00093669-01 | AMY38493 | 6

Especificaciones y pureza

≥97%

Condiciones de almacenamiento de almacenamiento

Protected from light, Room temperature

Enviado en

Normal

Pureza

≥97%

Nombres e identificadores

• Sonrisas canónicas: CC(C)(C)C1=CC2=CC(=C(C=C2C=C1)C#N)C#N
• IUPAC Name: 6-tert-butylnaphthalene-2,3-dicarbonitrile
• InChIKey: MKILROQBJOOZKC-UHFFFAOYSA-N
• INCHI: 1S/C16H14N2/c1-16(2,3)15-5-4-11-6-13(9-17)14(10-18)7-12(11)8-15/h4-8H,1-3H3
• Isómeros SMILES: CC(C)(C)C1=CC2=CC(=C(C=C2C=C1)C#N)C#N
• Peso molecular: 234.30
• Reaxy-Rn: 2647143
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2647143&ln=

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: DMSO: 2.35 mg/mL (10.01 mM), Sonication is recommended
• Sensibilidad: Light sensitive
• Peso molecular: 234.290 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 234.116 Da
• Monoisotopic Mass: 234.116 Da
• Topological Polar Surface Area: 47.600 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 400.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1