6-Thio-GTP (aqueous solution) (Thiogtp) - ≥95% , CAS No.17670-19-8

CAS: 17670-19-8 Cat. No.: T276292 Peso molecular: 539.25 PubChem CID: 3036888

GRADE & PURITY ≥95%

Synonyms

6-Thioguanosine-5'-O-triphosphate sodium salt | 6-Thioguanosine 5'-triphosphate | 6-T-GTP | Thiogtp | [[(2R,3S,4R,5S)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate | 6-Thioguanos

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C (desiccating conditions).

Specifications

Sinónimos

6-Thioguanosine-5'-O-triphosphate sodium salt | 6-Thioguanosine 5'-triphosphate | 6-T-GTP | Thiogtp | [[(2R, 3S, 4R, 5S)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3, 4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate | 6-Thioguanos

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

Vac-1-Rac signaling inhibitor. Azathioprine metabolite. 6-mercaptopurine derivative. Inhibits TNF-α-induced downstream signaling via JNK. Reduces c-Jun, transcription factor-2 and NF-κB activation. Shows immunosuppressant effects

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥95%

Nombres e identificadores

• Sonrisas canónicas: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)NC(=NC2=S)N
• IUPAC Name: [[(2R,3S,4R,5S)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
• InChIKey: QENYANNAQSWPLM-BDXYJKHTSA-N
• INCHI: 1S/C10H16N5O13P3S/c11-10-13-7-4(8(32)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-3,5-6,9,16-17H,1H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,32)/t3-,5-,6-,9+/m1/s1
• Isómeros SMILES: C1=NC2=C(N1[C@@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)NC(=NC2=S)N
• PubChem CID: 3036888
• Peso molecular: 539.25

Propiedades químicas y físicas

• Solubilidad: Supplied in water (10 mM)