7-O-(Amino-PEG4)-paclitaxel - ≥99.8% , CAS No.O767769

CAS: O767769 Cat. No.: O767769 Peso molecular: 1101.19

GRADE & PURITY ≥99.8%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

7-O - (Amino-PEG4) - paclitaxel is a PEG based drug linker conjugate used for ADC, comprising a paclitaxel moiety and an amino group. Amino groups can react with carboxylic acids, activated NHS esters, carbonyl groups (ketones, aldehydes), etc. 7-O - (Amino-PEG4) - paclitaxel can be used for the synthesis of ADCs.

Powder -20°C 3 years；In solvent -80°C 6 months，-20°C 1 month

In vitro research

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Specifications

Especificaciones y pureza

≥99.8%

Mecanismos bioquímicos y fisiológicos

7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclit

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99.8%

Nombres e identificadores

• Peso molecular: 1101.19