8-Aminoadenine - ≥98%(HPLC) , CAS No.28128-33-8

CAS: 28128-33-8 Cat. No.: A288024 Peso molecular: 150.14

GRADE & PURITY ≥98%(HPLC)

Synonyms

1H-Purine-6,8-diamine (9CI) | 1H-Purine-6,8-diamine | SCHEMBL42313 | Q88 | NSC21698 | NSC-21698 | A923992 | 7H-purine-6,8-diamine | AKOS025244128 | AKOS024457949 | 8-Aminoadenine | 9H-Purine-6,8-diamine | DTXSID20402507 | Q27464691 | C15483 | AB-323/40464

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Sinónimos

1H-Purine-6, 8-diamine (9CI) | 1H-Purine-6, 8-diamine | SCHEMBL42313 | Q88 | NSC21698 | NSC-21698 | A923992 | 7H-purine-6, 8-diamine | AKOS025244128 | AKOS024457949 | 8-Aminoadenine | 9H-Purine-6, 8-diamine | DTXSID20402507 | Q27464691 | C15483 | AB-323/40464

Especificaciones y pureza

≥98%(HPLC)

Mecanismos bioquímicos y fisiológicos

Adenine receptor agonist (Ki= 0.0341μM in HEK293 cells expressing an adenine binding site). Displays 190-fold increased potency at the human binding site over the rat adenine receptor (rAde1R) (Ki= 6.51μM).

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: C1=NC(=C2C(=N1)N=C(N2)N)N
• IUPAC Name: 7H-purine-6,8-diamine
• InChIKey: PFUVOLUPRFCPMN-UHFFFAOYSA-N
• INCHI: 1S/C5H6N6/c6-3-2-4(9-1-8-3)11-5(7)10-2/h1H,(H5,6,7,8,9,10,11)
• Isómeros SMILES: C1=NC(=C2C(=N1)N=C(N2)N)N
• Peso molecular: 150.14
• Reaxy-Rn: 9614
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9614&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Imidazopyrimidines
      • Subclass Purines and purine derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Imidazopyrimidines
• Subclass: Purines and purine derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: 6-aminopurines
• Alternative Parents: Aminopyrimidines and derivatives Imidolactams Aminoimidazoles Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-aminopurine - Aminopyrimidine - Imidolactam - Pyrimidine - Aminoimidazole - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 6-aminopurines. These are purines that carry an amino group at position 6. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Solvent:2eq.HCl, Max Conc. mg/mL: 15.01, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 7.51, Max Conc. mM: 50
• Peso molecular: 150.140 g/mol
• XLogP3: -0.600
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 150.065 Da
• Monoisotopic Mass: 150.065 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 150.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1