8-CPT-2Me-cAMP, sodium salt - ≥99%(HPLC) , CAS No.634207-53-7

CAS: 634207-53-7 Cat. No.: C287878 Peso molecular: 507.82 PubChem CID: 23679067

GRADE & PURITY ≥99%(HPLC)

Synonyms

sodium;9-[(4aR,6R,7R,7aR)-7-methoxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine;hydrate | 8-CPT-2Me-cAMP, sodium salt | Sodium (4aR,6R,7R,7aR)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

sodium;9-[(4aR, 6R, 7R, 7aR)-7-methoxy-2-oxido-2-oxo-4a, 6, 7, 7a-tetrahydro-4H-furo[3, 2-d][1, 3, 2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine;hydrate | 8-CPT-2Me-cAMP, sodium salt | Sodium (4aR, 6R, 7R, 7aR)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl

Especificaciones y pureza

≥99%(HPLC)

Mecanismos bioquímicos y fisiológicos

Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC50= 2.2μM), but not PKA (EC50> 10μM). Stimulates Epac-mediated Ca2+-mediated Ca2+release in pancreaticβ-cellsin vitro.Cell permeable a

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

ACTIVATOR

Pureza

≥99%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: COC1C2C(COP(=O)(O2)[O-])OC1N3C4=NC=NC(=C4N=C3SC5=CC=C(C=C5)Cl)N.O.[Na+]
• IUPAC Name: sodium;9-[(4aR,6R,7R,7aR)-7-methoxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-chlorophenyl)sulfanylpurin-6-amine;hydrate
• InChIKey: NVPSOXGMFVFZIS-IPBMGFFTSA-M
• INCHI: 1S/C17H17ClN5O6PS.Na.H2O/c1-26-13-12-10(6-27-30(24,25)29-12)28-16(13)23-15-11(14(19)20-7-21-15)22-17(23)31-9-4-2-8(18)3-5-9;;/h2-5,7,10,12-13,16H,6H2,1H3,(H,24,25)(H2,19,20,21);;1H2/q;+1;/p-1/t10-,12-,13-,16-;;/m1../s1
• Isómeros SMILES: CO[C@@H]1[C@H]2[C@@H](COP(=O)(O2)[O-])O[C@H]1N3C4=NC=NC(=C4N=C3SC5=CC=C(C=C5)Cl)N.O.[Na+]
• PubChem CID: 23679067
• Peso molecular: 507.82

Propiedades químicas y físicas

• Solubilidad: Solvent:water, Max Conc. mg/mL: 50.78, Max Conc. mM: 100