9-Fenantrol - Moligand™, calidad técnica , Channel blocker of TRPM4, CAS No.484-17-3, Channel blocker of TRPM4

CAS: 484-17-3 Cat. No.: P136335 Peso molecular: 194.23 Número EC: 207-602-4 PubChem CID: 10229
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. Technical grade ? Technical grade — industrial-quality purity with no tight impurity guarantees. Use for large-scale or non-critical processes where cost matters most.
Synonyms
HY-108457 | NSC50554 | NSC-50554 | UNII-9FYU45OV9H | DTXCID7027592 | DZKIUEHLEXLYKM-UHFFFAOYSA- | 4-06-00-04937 (Beilstein Handbook Reference) | Tox21_300618 | BRN 2047057 | GTPL4114 | SY113803 | Phenanthren-9-ol | SCHEMBL508755 | BDBM50526033 | CCRIS 184
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
250mg
P136335-250mg
3
54,90US$
1g
P136335-1g
1
147,90US$
5g
P136335-5g
1
543,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, calidad técnica Moligand™,Technical grade for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
HY-108457 | NSC50554 | NSC-50554 | UNII-9FYU45OV9H | DTXCID7027592 | DZKIUEHLEXLYKM-UHFFFAOYSA- | 4-06-00-04937 (Beilstein Handbook Reference) | Tox21_300618 | BRN 2047057 | GTPL4114 | SY113803 | Phenanthren-9-ol | SCHEMBL508755 | BDBM50526033 | CCRIS 184
Especificaciones y pureza
Moligand™, calidad técnica
Mecanismos bioquímicos y fisiológicos
Bloqueante selectivo de TRPM4 (IC 50 = 20 μM). Modula la contracción del músculo liso. Reduce la muerte celular inducida por LPS. Favorece la angiogénesis. Muestra efectos cardioprotectores y antiisquémicos in vivo.
Condiciones de almacenamiento de almacenamiento
Room temperature
Enviado en
Normal
Grado
Moligand™, Technical grade
Tipo de acción
CHANNEL BLOCKER
Mecanismo de acción
Channel blocker of TRPM4
Nota
¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.
Nombres e identificadores
Pubchem Sid504751916
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504751916
Sonrisas canónicasC1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O
IUPAC Namephenanthren-9-ol
InChIKeyDZKIUEHLEXLYKM-UHFFFAOYSA-N
INCHI1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
Isómeros SMILES C1=CC=C2C(=C1)C=C(C3=CC=CC=C23)O
WGK Alemania 3
RTECS SF8288000
PubChem CID 10229
Peso molecular 194.23

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClasePhenanthrenes and derivatives
SubclassPhenanthrols
Intermediate Tree Nodes Not available
Direct ParentPhenanthrols
Alternative Parents Naphthols and derivatives  1-hydroxy-2-unsubstituted benzenoids  Organooxygen compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Phenanthrol - 1-naphthol - 2-naphthol - Naphthalene - 1-hydroxy-2-unsubstituted benzenoid - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homopolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as phenanthrols. These are compounds containing a phenanthrene (or its hydrogenated derivative) to which a hydroxyl group is attached.
External Descriptors phenanthrol
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HL-60 (67320 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
A2226113Certificate of AnalysisAug 11, 2025 P136335
L2405186Certificate of AnalysisSep 06, 2024 P136335
D1903146Certificate of AnalysisDec 08, 2022 P136335
Propiedades químicas y físicas
Peso molecular194.230 g/mol
XLogP33.600
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass194.073 Da
Monoisotopic Mass194.073 Da
Topological Polar Surface Area20.200 Ų
Heavy Atom Count15
Formal Charge0
Complexity225.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
Referencias
1. Chun-Ying Xu, Yuan-Yuan Cui, Cheng-Xiong Yang.  (2023)  Fabrication of magnetic Fe3O4 doped β-cyclodextrin microporous organic network for the efficient extraction of endocrine disrupting chemicals from food takeaway boxes.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:38171066] [10.1016/j.chroma.2023.464625]
2. Kai Hu, Tiantian Pang, Cheng Yang, Pengzhao Han, Lixin Li, Pan Wang, Zhenqiang Zhang, Wenjie Zhao, Shusheng Zhang.  (2023)  Simultaneous extraction of hydroxylated polycyclic aromatic hydrocarbons and catecholamines with magnetic boronic acid hypercrosslinked polymers.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:37931428] [10.1016/j.chroma.2023.464491]
3. Zhengwen Wei, Yifan Du, Xiang-fei Lü, Wei Wang, Roberta Del Sole, Giuseppe Mele, Zhen-Yi Jiang.  (2022)  High-performance Fe3O4-terephthalaldehyde magnetic-nanocomposite for removal phenanthrene and 9-phenanthrol: A comprehensive experimental and theoretical analysis.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2022.122610]
4. Zhengwen Wei, Xiang-fei Lü, Wei Wang, Giuseppe Mele, Zhen-Yi Jiang.  (2022)  Excellent removal performance of 4,4'-biphenyldicarboxaldehyde m-phenylenediamine Schiff base magnetic polymer towards phenanthrene and 9-phenanthrol: Experimental, modeling and DFT calculations studies.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:36099739] [10.1016/j.jhazmat.2022.129920]
5. Zhengwen Wei, Xiang-fei Lü, Wei Wang, Giuseppe Mele, Zhen-Yi Jiang.  (2022)  Fe3O4-4,4′-biphenyldicarboxaldehyde superparamagnetic-nanomaterial for the high-efficiency removal of 9-phenanthrol: experimental combined with DFT investigations.  Environmental Science-Nano,  (9): (3562-3580).  [PMID:] [10.1039/D2EN00543C]
6. Sun Fei, Feng Chao, Wang Yang, Yang Xue, Zhao Hong.  (2022)  Preparation of fluorescent polystyrene microspheres by improving swelling performance based on molecular weight and surface carboxyl group content.  QUIMICA NOVA,  45  (2): (145-151).  [PMID:] [10.21577/0100-4042.20170808]
7. Xin-Qiao He, Yuan-Yuan Cui, Cheng-Xiong Yang.  (2021)  Thiol–Yne Click Postsynthesis of a Sulfonate Group-Enriched Magnetic Microporous Organic Network for Efficient Extraction of Benzimidazole Fungicides.  ACS Applied Materials & Interfaces,      [PMID:34374514] [10.1021/acsami.1c11148]
8. Xin-Qiao He, Yuan-Yuan Cui, Xiao-Hui Lin, Cheng-Xiong Yang.  (2021)  Fabrication of polyethyleneimine modified magnetic microporous organic network nanosphere for efficient enrichment of non-steroidal anti-inflammatory drugs from wastewater samples prior to HPLC-UV analysis.  TALANTA,      [PMID:34215105] [10.1016/j.talanta.2021.122471]
9. Fan Libing, Ma Qianli, Tian Jiao, Li Dan, Xi Xue, Dong Xiangting, Yu Wensheng, Wang Jinxian, Liu Guixia.  (2019)  Conjugate Electrospinning Construction of Microyarns with Synchronous Color-Tuned Photoluminescence and Tunable Electrical Conductivity.  JOURNAL OF ELECTRONIC MATERIALS,  48  (3): (1511-1521).  [PMID:] [10.1007/s11664-018-06914-9]
10. Zhongyue Zhou, Haoran Liu, Xinghua Liu, Chih-Hao Chin.  (2025)  Oxygenated Polycyclic Aromatic Hydrocarbons as Key Coke Precursors in Coke Formation during Zeolite-Catalyzed Furfural Pyrolysis.  Applications in Energy and Combustion Science,      [PMID:] [10.1016/j.jaecs.2025.100389]
11. Jin Chen, Yiwei Fang, Borui Sun, Ying Xu, Wanyi Chen, Kai zhao, Huiping Zhang.  (2025)  Association between polycyclic aromatic hydrocarbons exposure and gestational hypertension: Insights from global and dose metabolomics analysis.  Journal of Environmental Sciences,      [PMID:41461512] [10.1016/j.jes.2025.05.030]
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