The store will not work correctly when cookies are disabled.
Parece que JavaScript está deshabilitado en su navegador. Para obtener la mejor experiencia en nuestro sitio, asegúrese de activar Javascript en su navegador.
· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items A-1210477 - ≥98% , CAS No.1668553-26-1
Synonyms
7-[5-[[4-[4-[(Dimetilamino)sulfonil]-1-piperazinil]fenoxi]metil]-1,3-dimetil-1H-pirazol-4-il]-1-[2-(4-morfolinil)etil]-3-[3-(1-naftaleniloxi)propil]-1H-indole-2-carboxilicacido | 7-(1,3-Dimetil-5-((4-(4-(metilsulfonil)piperazin-1-il)fenoxi)metil
Storage
Conservar a -20°C,Desecado
Shipped In
Hielera + almohadillas de hielo
🧪
Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
🌡
Storage & shipping Conservar a -20°C,Desecado Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
📋
Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
📚
Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Enviado a 4°C. Almacenar a -20°C. Almacenar en condiciones de desecación.
Specifications Sinónimos
7-[5-[[4-[4-[(Dimetilamino)sulfonil]-1-piperazinil]fenoxi]metil]-1, 3-dimetil-1H-pirazol-4-il]-1-[2-(4-morfolinil)etil]-3-[3-(1-naftaleniloxi)propil]-1H-indole-2-carboxilicacido | 7-(1, 3-Dimetil-5-((4-(4-(metilsulfonil)piperazin-1-il)fenoxi)metil
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Inhibidor potente y selectivo de MCL-1 con K i e IC 50 de 0, 454 nM y 26, 2 nM, respectivamente, con una selectividad >100 veces superior a la de otros miembros de la familia Bcl-2. Permeable a las células. Se une a MCL-1 de forma selectiva y con afinidad s
Condiciones de almacenamiento de almacenamiento
Conservar a -20°C, Desecado
Enviado en
Hielera + almohadillas de hielo
Nota
Siempre que sea posible, prepare y utilice las soluciones el mismo día. Sin embargo, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.
Nombres e identificadores Pubchem Sid 504771839 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504771839 Sonrisas canónicas CC1=NN(C(=C1C2=CC=CC3=C2N(C(=C3CCCOC4=CC=CC5=CC=CC=C54)C(=O)O)CCN6CCOCC6)COC7=CC=C(C=C7)N8CCN(CC8)S(=O)(=O)N(C)C)C IUPAC Name 7-[5-[[4-[4-(dimethylsulfamoyl)piperazin-1-yl]phenoxy]methyl]-1,3-dimethylpyrazol-4-yl]-1-(2-morpholin-4-ylethyl)-3-(3-naphthalen-1-yloxypropyl)indole-2-carboxylic acid InChIKey XMVAWGSQPHFXKU-UHFFFAOYSA-N INCHI 1S/C46H55N7O7S/c1-33-43(41(49(4)47-33)32-60-36-19-17-35(18-20-36)51-22-24-52(25-23-51)61(56,57)48(2)3)40-14-8-13-38-39(15-9-29-59-42-16-7-11-34-10-5-6-12-37(34)42)45(46(54)55)53(44(38)40)26-21-50-27-30-58-31-28-50/h5-8,10-14,16-20H,9,15,21-32H2,1-4H3,(H,54,55) Isómeros SMILES CC1=NN(C(=C1C2=CC=CC3=C2N(C(=C3CCCOC4=CC=CC5=CC=CC=C54)C(=O)O)CCN6CCOCC6)COC7=CC=C(C=C7)N8CCN(CC8)S(=O)(=O)N(C)C)C Peso molecular 850.04 Reaxy-Rn 28394619 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28394619&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Diazinanes Subclass Piperazines Intermediate Tree Nodes Not available Direct Parent Phenylpiperazines Alternative Parents Indolecarboxylic acids and derivatives N-arylpiperazines 3-alkylindoles Piperazinesulfonamides Naphthalenes N-alkylindoles Aminophenyl ethers Pyrrole 2-carboxylic acids Aniline and substituted anilines Phenoxy compounds Dialkylarylamines Alkyl aryl ethers Sulfuric acid diamides Substituted pyrroles Morpholines Heteroaromatic compounds Pyrazoles Trialkylamines Amino acids Oxacyclic compounds Dialkyl ethers Carboxylic acids Azacyclic compounds Hydrocarbon derivatives Organic oxides Molecular Framework Aromatic heteropolycyclic compounds Substituents Indolecarboxylic acid derivative - Phenylpiperazine - N-arylpiperazine - Naphthalene - N-alkylindole - Piperazine-1-sulfonamide - 3-alkylindole - Indole - Aminophenyl ether - Indole or derivatives - Phenoxy compound - Phenol ether - Pyrrole-2-carboxylic acid - Pyrrole-2-carboxylic acid or derivatives - Dialkylarylamine - Aniline or substituted anilines - Alkyl aryl ether - Substituted pyrrole - Monocyclic benzene moiety - Benzenoid - Oxazinane - Sulfuric acid diamide - Morpholine - Pyrrole - Pyrazole - Azole - Heteroaromatic compound - Organic sulfuric acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Amino acid - Azacycle - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Dialkyl ether - Ether - Amine - Hydrocarbon derivative - Organooxygen compound - Organic nitrogen compound - Organonitrogen compound - Organic oxygen compound - Organic oxide - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Soluble in DMSO to 3 mM (with warming) Peso molecular 850.000 g/mol XLogP3 3.600 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 12 Rotatable Bond Count 16 Exact Mass 849.388 Da Monoisotopic Mass 849.388 Da Topological Polar Surface Area 143.000 Ų Heavy Atom Count 61 Formal Charge 0 Complexity 1500.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Calculadoras de soluciones Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator Determine the dilution needed to prepare a stock solution.
Reconstitution Calculator Reseñas
We use cookies to ensure the website functions properly and, where permitted, to improve your experience. You can manage your preferences at any time in Settings. Learn more in our
Cookie Policy. Configuración Aceptar todo Rechazar
Shall we send you a message when we have discounts available?
Remind me later Permitir
Thank you! Please check your email inbox to confirm.
Oops! Notifications are disabled.
Products are supplied to verified businesses, institutions, and qualified professionals for research and development use only. Not for use in humans, animals, diagnosis, or therapy.
Copyright © 2023–present Aladdin Scientific Corp. All rights reserved.
L2203078