A 889425 - ≥99% , CAS No.1072921-02-8

CAS: 1072921-02-8 Cat. No.: A275024 Fórmula: C₁₉H₁₈F₃N₃O₃S Peso molecular: 425.42 PubChem CID: 76848882

GRADE & PURITY ≥99%

Synonyms

N-(3-metilpiridin-2-il)-1-[4-(trifluorometilsulfonil)fenil]-3,6-dihidro-2H-piridin-4-carboxamida

Storage

Conservar a -20°C,Desecado

Shipped In

Hielera + almohadillas de hielo

Descripción general

Almacenar a -20°C. Almacenar en condiciones de desecación. El producto puede almacenarse hasta 12 meses.

Specifications

Sinónimos

N-(3-metilpiridin-2-il)-1-[4-(trifluorometilsulfonil)fenil]-3,6-dihidro-2H-piridin-4-carboxamida

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Potent, selective TRPV1 antagonist (IC 50 values are 335 and 34 nM for rat and human TRPV1 respectively). Inhibits mechanotransmission in inflamed skin. Shows antinociceptive effects in vivo. Orally active.

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C,Desecado

Enviado en

Hielera + almohadillas de hielo

Tipo de acción

ANTAGONIST

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥99%

Nombres e identificadores

Sonrisas canónicas

CC1=C(N=CC=C1)NC(=O)C2=CCN(CC2)C3=CC=C(C=C3)S(=O)(=O)C(F)(F)F

IUPAC Name

N-(3-methylpyridin-2-yl)-1-[4-(trifluoromethylsulfonyl)phenyl]-3,6-dihydro-2H-pyridine-4-carboxamide

InChIKey

KACDTVMXDRFPPA-UHFFFAOYSA-N

INCHI

1S/C19H18F3N3O3S/c1-13-3-2-10-23-17(13)24-18(26)14-8-11-25(12-9-14)15-4-6-16(7-5-15)29(27,28)19(20,21)22/h2-8,10H,9,11-12H2,1H3,(H,23,24,26)

Isómeros SMILES

CC1=C(N=CC=C1)NC(=O)C2=CCN(CC2)C3=CC=C(C=C3)S(=O)(=O)C(F)(F)F

PubChem CID

76848882

Peso molecular

425.42

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO to 100 mM