α-Thrombin , CAS No.9002-04-4

CAS: 9002-04-4 Cat. No.: np330890 Fórmula: C₁₂H₁₀ClN₃S Peso molecular: 263.75 Número EC: 232-648-7 PubChem CID: 65045

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Accession #

P00734

Bioactivity

≥2700 NIH U/mg protein

Descripción general

The Human Thrombin was activated from homogeneous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. These activating enzymes were removed after activation. Complete activation was observed on SDS-PAGE. This activated enzyme has a minimum activity of 2,700 NIH units/mg when compared to NIH standard thrombin.

Extinction Coefficient (1%) = 18.3 

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Protein is for research use only; not for human use.

Specifications

Product Name

α-Thrombin , CAS No.9002-04-4

Sinónimos

Human Alpha Thrombin | Human α-Thrombin | Human alpha-Thrombin Native Protein | Factor IIa, Human Plasma | Coagulation factor IIa | F2 | PT | THPH1 | RPRGL2

Grado

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Especificaciones y pureza

Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Mecanismos bioquímicos y fisiológicos

Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Activates coagulation

Bioactividad

≥2700 NIH U/mg protein

Número de adhesión

P00734

Peso molecular previsto

37 kDa

CAS

9002-04-4

Número de la Comisión de Enzimas

EC 3.4.21.5

Tipo de molécula

Enzyme

Product Line

biological_products

Propiedades del producto

Nacres

NA.54

Almacenamiento y envío

Concentración

from Human plasma; ≥2700 NIH U/mg protein; Pre-lyophilization Protein Concentration: See COA

Reconstitución

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C

Enviado en

Wet ice

Estabilidad y almacenamiento

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.