Ac2-26 TFA salt, Agonist of FPR1;Agonist of FPR2/ALX;Agonist of FPR3, CAS No.151988-33-9(free), Agonist of FPR1;Agonist of FPR2/ALX;Agonist of FPR3

CAS: 151988-33-9(free) Cat. No.: A288593 Peso molecular: 3089.46(free)

GRADE & PURITY Moligand™, ≥95%

Descripción general

Ac2-26 TFA, an active N-terminal peptide of annexin A1 (AnxA1), attenuates ischemia-reperfusion-induced acute lung injury. Ac2-26 also decreases AnxA1 protein expression, inhibits the activation of NF-κB and MAPK pathways in the injured lung tissue。

Specifications

Product Name

Ac2-26 TFA salt, Agonist of FPR1;Agonist of FPR2/ALX;Agonist of FPR3, CAS No.151988-33-9(free)

Grado

Moligand™

Especificaciones y pureza

Moligand™, ≥95%

Mecanismos bioquímicos y fisiológicos

Annexin/lipocortin 1-mimetic peptide; inhibits leukocyte extravasation. Reduces neutrophil adhesion and emigration, promotes detachment of neutrophils from activated mesenteric endothelium and accelerates epithelial wound repair after induced colonic inju

Secuencia

AMVSEFLKQAWFIENEEQEYVQTVK(Modifications: Ala-1 = N-terminal Ac)

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of FPR1;Agonist of FPR2/ALX;Agonist of FPR3

CAS

151988-33-9(free)

Tipo de molécula

Small molecule

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C,Desiccated

Enviado en

Ice chest + Ice pads

Objetivos asociados (humanos)

FPR1 Tchem fMet-Leu-Phe receptor (0 Activities)

Discover Target: FPR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FPR2 Tchem N-formyl peptide receptor 2 (0 Activities)

Discover Target: FPR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FPR3 Tchem N-formyl peptide receptor 3 (0 Activities)

Discover Target: FPR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Información genética

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