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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items ACT 462206 - Moligand™, ≥99%(HPLC) , Antagonist of OX 1 receptor;Antagonist of OX 2 receptor, CAS No.1361321-96-1, Antagonist of OX 1 receptor;Antagonist of OX 2 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%(HPLC) Synonyms
ACT 462206 | MS-26450 | NCGC00387479-01 | (S)-N-(3,5-dimethylphenyl)-1-((4-methoxyphenyl)sulfonyl)-pyrrolidine-2-carboxamide | ACT462206 | ACT-462206 | ACT-462206, >=98% (HPLC) | (2~{S})-~{N}-(3,5-dimethylphenyl)-1-(4-methoxyphenyl)sulfonyl-pyrrolidine-2-
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Why this grade Moligand™, ≥99%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
ACT 462206 | MS-26450 | NCGC00387479-01 | (S)-N-(3, 5-dimethylphenyl)-1-((4-methoxyphenyl)sulfonyl)-pyrrolidine-2-carboxamide | ACT462206 | ACT-462206 | ACT-462206, >=98% (HPLC) | (2~{S})-~{N}-(3, 5-dimethylphenyl)-1-(4-methoxyphenyl)sulfonyl-pyrrolidine-2-
Especificaciones y pureza
Moligand™, ≥99%(HPLC)
Mecanismos bioquímicos y fisiológicos
Potent, dual orexin receptor antagonist (IC50values are 11 and 60 nM for OX2and OX1receptors respectively). Exhibits anxiolytic-like propertiesin vivo. Brain penetrant.ACT-462206 is a orally active, brain penetrant, potent and selective dual orexin1/2 rec
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Mecanismo de acción
Antagonist of OX 1 receptor;Antagonist of OX 2 receptor
Nombres e identificadores Pubchem Sid 504770170 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504770170 Sonrisas canónicas CC1=CC(=CC(=C1)NC(=O)C2CCCN2S(=O)(=O)C3=CC=C(C=C3)OC)C IUPAC Name (2S)-N-(3,5-dimethylphenyl)-1-(4-methoxyphenyl)sulfonylpyrrolidine-2-carboxamide InChIKey NHPQGZOBHSVTAQ-IBGZPJMESA-N INCHI 1S/C20H24N2O4S/c1-14-11-15(2)13-16(12-14)21-20(23)19-5-4-10-22(19)27(24,25)18-8-6-17(26-3)7-9-18/h6-9,11-13,19H,4-5,10H2,1-3H3,(H,21,23)/t19-/m0/s1 Isómeros SMILES CC1=CC(=CC(=C1)NC(=O)[C@@H]2CCCN2S(=O)(=O)C3=CC=C(C=C3)OC)C CAS alternativo 1361321-96-1 PubChem CID 40924317 Términos de entrada MeSH ACT-462206 Peso molecular 388.48
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Clase Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent Proline and derivatives Alternative Parents Alpha amino acid amides Benzenesulfonamides Anilides Benzenesulfonyl compounds m-Xylenes Anisoles Pyrrolidinecarboxamides Methoxybenzenes N-arylamides Phenoxy compounds Alkyl aryl ethers Organosulfonamides Sulfonyls Secondary carboxylic acid amides Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides Molecular Framework Aromatic heteromonocyclic compounds Substituents Proline or derivatives - Alpha-amino acid amide - Benzenesulfonamide - Benzenesulfonyl group - Anilide - Phenoxy compound - Anisole - M-xylene - Xylene - Phenol ether - Methoxybenzene - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - N-arylamide - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Organosulfonic acid amide - Organic sulfonic acid or derivatives - Pyrrolidine - Organosulfonic acid or derivatives - Sulfonyl - Secondary carboxylic acid amide - Carboxamide group - Organoheterocyclic compound - Azacycle - Ether - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Carbonyl group - Organosulfur compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as proline and derivatives. These are compounds containing proline or a derivative thereof resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:DMSO, Max Conc. mg/mL: 38.85, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 38.85, Max Conc. mM: 100 Peso molecular 388.500 g/mol XLogP3 3.200 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 5 Exact Mass 388.146 Da Monoisotopic Mass 388.146 Da Topological Polar Surface Area 84.100 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 600.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 1 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
Calculadoras de soluciones Molarity Calculator Determine the necessary mass, volume, or concentration for preparing a solution.
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Reconstitution Calculator Reseñas Need help choosing the grade? Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
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