Adenosine 3′,5′-diphosphate disodium salt - ≥96% , CAS No.75431-54-8

CAS: 75431-54-8 Cat. No.: A356408 Peso molecular: 471.16 Número EC: 636-050-0

GRADE & PURITY ≥96%

Synonyms

3'-Adenylic acid,5'-(dihydrogen phosphate), disodium salt (9CI) | 3'-Phosphoadenosine 5'-phosphate | [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy(oxido)phosphoryl]oxymethyl]oxolan-3-yl] hydrogen phosphate | 腺苷 3′,5′-二磷酸 二钠盐

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

3′-phosphoadenosine 5′-phosphate (PAP), a 3′-phosphorylated nucleotide is found in almost all organisms and is obtained as a by-product of sulfur and lipid metabolism. 

Purpose

Adenosine 3′,5′-diphosphate disodium salt has been used:
to spot sample on cellulose high-performance thin-layer chromatography (HPTLC) plates in two-dimensional thin layer chromatography
in enzyme activity assay to study the activities of HOS2/FIERY1 wild type
hos2 mutant and fiery1?2 mutant protein against 3′-phosphoadenosine 5′-phosphate (PAP)
as a standard for the quantification of phosphoadenosines

Specifications

Sinónimos

3'-Adenylic acid, 5'-(dihydrogen phosphate), disodium salt (9CI) | 3'-Phosphoadenosine 5'-phosphate | [(2R, 3S, 4R, 5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy(oxido)phosphoryl]oxymethyl]oxolan-3-yl] hydrogen phosphate | 腺苷 3′, 5′-二磷酸 二钠盐

Especificaciones y pureza

≥96%

Mecanismos bioquímicos y fisiológicos

3′-phosphoadenosine 5′-phosphate (PAP) is capable of blocking exoribonucleases (XRNs) activity in the nucleus and cytosol. It stimulates stomatal closure and can serve as a secondary messenger during abscisic acid (ABA) signaling. It is capable of blockin

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Tipo de acción

INHIBITOR

Pureza

≥96%

Nombres e identificadores

• Pubchem Sid: 504772595
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504772595
• Sonrisas canónicas: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)[O-])OP(=O)(O)[O-])O)N.[Na+].[Na+]
• IUPAC Name: disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy(oxido)phosphoryl]oxymethyl]oxolan-3-yl] hydrogen phosphate
• InChIKey: PQHHAKIJTDLQLS-IDIVVRGQSA-L
• INCHI: 1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7(25-27(20,21)22)4(24-10)1-23-26(17,18)19;;/h2-4,6-7,10,16H,1H2,(H2,11,12,13)(H2,17,18,19)(H2,20,21,22);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• Isómeros SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)[O-])OP(=O)(O)[O-])O)N.[Na+].[Na+]
• WGK Alemania: 3
• CAS alternativo: 1053-73-2
• Peso molecular: 471.16

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleotides
      • Subclass Purine ribonucleotides
        • Level5 Purine ribonucleoside bisphosphates
          • Level6 Purine ribonucleoside 3',5'-bisphosphates

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleotides
• Subclass: Purine ribonucleotides
• Intermediate Tree Nodes: Purine ribonucleoside bisphosphates
• Direct Parent: Purine ribonucleoside 3',5'-bisphosphates
• Alternative Parents: Ribonucleoside 3'-phosphates Pentose phosphates Glycosylamines 6-aminopurines Monosaccharide phosphates Aminopyrimidines and derivatives Alkyl phosphates Imidolactams N-substituted imidazoles Heteroaromatic compounds Oxolanes Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives Organic oxides Organic sodium salts Organic zwitterions
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine ribonucleoside 3',5'-bisphosphate - Ribonucleoside 3'-phosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Imidolactam - Pyrimidine - Alkyl phosphate - Azole - Oxolane - Imidazole - Heteroaromatic compound - Secondary alcohol - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Oxacycle - Organic salt - Alcohol - Organic nitrogen compound - Amine - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic sodium salt - Organic oxygen compound - Primary amine - Organic oxide - Organic zwitterion - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine ribonucleoside 3',5'-bisphosphates. These are purine ribobucleotides with one phosphate group attached to 3' and 5' hydroxyl groups of the ribose moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water (25 mg/ml).
• Punto de ebullición (°C): 924.3° C at 760 mmHg (Predicted)