Adenosine 5'-(α,β-methylene)diphosphate sodium salt - ≥98%(HPLC) , CAS No.89016-30-8

CAS: 89016-30-8 Cat. No.: A286760 Peso molecular: 447.21

GRADE & PURITY ≥98%(HPLC)

Synonyms

AMPCP, APCP | α,β-Methyleneadenosine 5'-diphosphate monosodium salt

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

AMPCP, APCP | α, β-Methyleneadenosine 5'-diphosphate monosodium salt

Especificaciones y pureza

≥98%(HPLC)

Mecanismos bioquímicos y fisiológicos

Ecto-5'-nucleotidase/CD73 inhibitor. Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells (MCF7/A6 and L1210/A). Also in

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(CP(=O)(O)[O-])O)O)O)N.[Na+]
• IUPAC Name: sodium;[[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methyl-hydroxyphosphinate
• InChIKey: RFGZKSPLJPHQMI-RDJRRFHDSA-M
• INCHI: 1S/C11H17N5O9P2.Na/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(25-11)1-24-27(22,23)4-26(19,20)21;/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H2,12,13,14)(H2,19,20,21);/q;+1/p-1/t5-,7-,8+,11-;/m1./s1
• Isómeros SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(CP(=O)(O)[O-])O)O)O)N.[Na+]
• Peso molecular: 447.21
• Reaxy-Rn: 55307629
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=55307629&ln=

Propiedades químicas y físicas

• Solubilidad: Soluble in water (supplied pre-dissolved at a concentration of 10mM)