10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Albendazole (SKF-62979) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.
In vitro
Albendazole is reported to be teratogenic in rats, and is extensively metabolized to the sulfoxide derivative. Albendazole and its sulfoxide metabolite elicit an accumulation of cells in the mitotic phase of the cell cycle.
In vivo
Albendazole causes an induction of hepatic activities of CYP1A1-associated ethoxyresorufin O-deethylase (EROD) 65 fold, CYP1A2-associated methoxyresorufin O-demethylase (MROD) 6 fold, CYP2B1-associated penthoxyresorufin O-dealkylase (PROD) 4 fold, CYP2B2-associated benzyloxyresorufin O-dealkylase (BROD) 14 fold, as well as a partial reduction of CYP2E1-associated 4-nitrophenol hydroxylase (4-NPH) activity in the rat. Albendazole is metabolized to its pharmacologically active sulfoxide metabolites by liver and lung microsomes from sheep and cattle, as well as by cattle intestinal microsomes. Albendazole (ABZ) is a benzimidazole derivative with a broad spectrum of activity against human and animal helminthe parasites. Albendazole and its metabolites are extensively distributed to the digestive tract, mainly into the abomasal fluid, after the i.v. and i.r. administrations. Albendazole and its active albendazole sulphoxide (ABZSO) metabolite are recovered in tapeworms collected from both i.v. and i.r. treated lambs.
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥97%
| ALogP | 2.9 |
|---|
| Isómeros SMILES | CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC |
|---|---|
| WGK Alemania | 2 |
| RTECS | FD1100000 |
| Peso molecular | 265.33 |
| Reaxy-Rn | 4193299 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4193299&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Solubilidad | Solubility (25°C) In vitro DMSO: 97 mg/mL (201.06 mM); |
|---|---|
| Punto de fusión (°C) | 208-210°C |
| 1. Qian Liu, Xiaoying Yang, Longhui Luo, Wei Tian, Chao Kang, Tao Sun, Yuegang Chen, Juan Tao, Dongmei Chen. (2025) Rapid detection of benzimidazole fungicides by electrostatic self-assembly of MXene@PEI@AgNPs composite SERS substrate combined with chemometrics. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2025.108171] |
| 2. Zhiwei Zhou, Yaohua Yan, Xing Li, Fanxi Zeng, Senlin Shao. (2023) Effect of urea-based chemical cleaning on TrOCs rejection by nanofiltration membranes. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2023.123662] |
| 3. Yiting Wen, Yujia Zhang, Xiaoli Zhang, Linjun Wang, Qiuxia Pan, Qiuhan Bai, Du Zhu, Weiming Chai. (2023) Inhibition of albendazole and 2-(2-aminophenyl)-1H-benzimidazole against tyrosinase: mechanism, structure–activity relationship, and anti-browning effect. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (6): (2824-2837). [PMID:36641547] [10.1002/jsfa.12450] |
| 4. Tianfeng Yang, Cheng Cheng, Rui Xu, Jian Huo, Xiujuan Peng, Yanbin Chen, Yonghong Liang, Zhiheng Su, Yanmin Zhang. (2022) Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway. LIFE SCIENCES, [PMID:36257459] [10.1016/j.lfs.2022.121086] |
| 5. Yaowei Guo, Jin Liu, Qinglin Tang, Cuicui Li, Yanying Zhang, Yao Wang, Yanxin Wang, Yupeng Bi, Christopher D. Snow, Matt J. Kipper, Laurence A. Belfiore, Jianguo Tang. (2022) Lanthanide (Eu3+/Tb3+)-Loaded γ-Cyclodextrin Nano-Aggregates for Smart Sensing of the Anticancer Drug Irinotecan. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (12): (6597). [PMID:35743042] [10.3390/ijms23126597] |
| 6. Lei Men, Yuhan Zhang, Keke Li, Zhongyu Li, Chunbin Li, Xueyuan Zhang, Xiaojie Gong, Linlin Fang. (2022) Metabolism and pharmacokinetics of mebendazole in Japanese pufferfish (Takifugu rubripes). Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, [PMID:35442868] [10.1080/19440049.2022.2052974] |
| 7. Jingfeng Li, Zhaoyi An, Junyang Sun, Chunyan Tan, Dan Gao, Ying Tan, Yuyang Jiang. (2020) Highly Selective Oxidation of Organic Sulfides by a Conjugated Polymer as the Photosensitizer for Singlet Oxygen Generation. ACS Applied Materials & Interfaces, [PMID:32658457] [10.1021/acsami.0c10162] |
| 8. Dongze Wang, Gang Chen, Xuemei Li, Qiong Jia. (2019) Hypercrosslinked β-cyclodextrin porous polymer as adsorbent for effective uptake towards albendazole from aqueous media. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2019.115720] |
| 9. Dongze Wang, Xuemei Li, Xiangqun Jin, Qiong Jia. (2019) Design of cucurbit[6]uril-based hypercrosslinked polymers for efficient capture of albendazole. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2019.01.065] |
| 10. Qin Li, Xuanping Tan, Lingli Fu, Qu Liu, Weiwei Tang. (2014) A novel fluorescence and resonance Rayleigh scattering probe based on quantum dots for the detection of albendazole. Analytical Methods, 7 (2): (614-620). [PMID:] [10.1039/C4AY02289K] |
| 11. Lan Sumin, Chen Kexi, Feng Liqiang, Sima Panle, Ji Xiaoyao, Wu Feihua, Lin Yining. (2025) Tea Saponins: a Novel Stabilizer for Enhancing the Oral Bioavailability of Albendazole Nanocrystals. AAPS PHARMSCITECH, 26 (1): (1-13). [PMID:39779633] [10.1208/s12249-024-03015-1] |
