EIA grade, from calf intestine EIA grade for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 53 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| 1. Bangbang Li, Yanchen Wang, Pengzhao Chang, Hao Chen, Yangang Zhu, Nanxin Zhao, Zhimou Yang, Jingjing Li. (2025) In situ enzyme instructed peptide assembly favoring a three-target sequentially responsive fluorescence probe for the early identification of atherosclerotic plaque in vivo. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.167162] |
| 2. Yueyuan Zhuang, Han Dong, Tianqing Liu, Yongmei Zhao, Yan Xu, Xiaojuan Zhao, Dan Sun. (2023) Highly sensitive and selective SERS detection of caspase-3 during cell apoptosis based on the target-induced hotspot effect. ANALYST, [PMID:38062995] [10.1039/D3AN01721D] |
| 3. Yu Liu, Fangfang Wang, Yawen Liu, Zhigang Zhang, Haiming Hu, Yiqing Wang, Lei Xiong, Junping Zheng, Hongtao Liu. (2023) A label-free AuNPs-based ultrasensitive plasmonic ELISA by alkaline phosphatase and ferrous ion-initiated cascade amplification. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2023.135049] |
| 4. Panwang Hu, Jinjin Liu, Changkun Xia, Bangxiang Liu, Hengjia Zhu, Xiangheng Niu. (2023) Matrix redox interference-free nanozyme-amplified detection of Hg2+ using thiol-modified phosphatase-mimetic nanoceria. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2023.135030] |
| 5. Jiansen Lie, Feili Luo, Yafang Liu, Yixuan Yang, Qingling Nie, Xiaochuan Chen, Ruiyun You, Yunzhen Liu, Xiufeng Xiao, Yudong Lu. (2023) Recyclable magnetic nanoparticles combined with TiO2 enrichment and “Off” to “On” SERS assay for sensitive detection of alkaline phosphatase. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.147241] |
| 6. Tengteng Liu, Dan Li, Na Li, Wei Zhang, Yong Zhao. (2023) Ultrasensitive quantifying copper ions in serum by tapered optical fiber fluorescent sensor based on static quenching effect. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2023.134557] |
| 7. haozhi Wang, Jinyu Lai, Xiaohui Xu, Wei Yu, Xinghua Wang. (2023) Combination of gold nanoclusters and silicon quantum dots for ratiometric fluorometry: One system, two mechanisms. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:38198882] [10.1016/j.jpba.2023.115940] |
| 8. Hui Dong, Le Zhao, Tao Wang, Yanan Chen, Wanqing Hao, Ziyi Zhang, Yizhao Hao, Cunliang Zhang, Xiuhua Wei, Yintang Zhang, Yanli Zhou, Maotian Xu. (2023) Dual-Mode Ratiometric Electrochemical and Turn-On Fluorescent Detection of Butyrylcholinesterase Utilizing a Single Probe for the Diagnosis of Alzheimer’s Disease. ANALYTICAL CHEMISTRY, [PMID:37192372] [10.1021/acs.analchem.3c00974] |
| 9. Yanwen Chen, Liu Zhao, Baoshuai Zhang, Yuqing Guan, Cheng Yao, Xuan Xu. (2023) Fe–N hollow mesoporous carbon spheres with high oxidase-like activity for sensitive detection of alkaline phosphatase. ANALYST, 148 (12): (2825-2833). [PMID:37227369] [10.1039/D3AN00475A] |
| 10. Hong Liu, Xuliang Yang, Bo Huang, Hongxiang Liu. (2023) A universal approach for synthesis of copper nanoclusters templated by G-rich oligonucleotide sequences and their applications in sensing. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:37080047] [10.1016/j.saa.2023.122740] |
| 11. Jiaxin Liu, Keke Ning, Yao Fu, Yujie Sun, Jiangong Liang. (2023) Sulfur quantum dots as a fluorescent sensor for N-acetyl-beta-D-glucosaminidase detection. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:36893676] [10.1016/j.saa.2023.122553] |
| 12. Kanglin Pei, Di Li, Wenjing Qi, Di Wu. (2023) Ultrarapid Microwave-Assisted Synthesis of Fluorescent Silver Coordination Polymer Nanoparticles and Its Application in Detecting Alkaline Phosphatase Activity. MOLECULES, 28 (4): (1892). [PMID:36838879] [10.3390/molecules28041892] |
| 13. Xinxin Ren, Qingqing Zhang, Lingxia Qin, Kaiyue Hu, Zhiyong Guo, Sui Wang, Yufang Hu. (2022) Checkerboard arranged G4 nanostructure-supported electrochemical platform and its application to unique bio-enzymes examination. BIOELECTROCHEMISTRY, [PMID:36242949] [10.1016/j.bioelechem.2022.108282] |
| 14. Nanjun Li, Chongyang Wang, Liangjun Chen, Cui Ye, Yongwu Peng. (2022) Ultrathin Covalent Organic Framework Nanosheets/Ti3C2Tx-Based Photoelectrochemical Biosensor for Efficient Detection of Prostate-Specific Antigen. MOLECULES, 27 (19): (6732). [PMID:36235265] [10.3390/molecules27196732] |
| 15. Lingxia Qin, Xinxin Ren, Kaiyue Hu, Di Wu, Zhiyong Guo, Sui Wang, Linwen Jiang, Yufang Hu. (2022) Supramolecular Host-Guest Interaction-Driven Electrochemical Recognition for Pyrophosphate and Alkaline Phosphatase Analysis. CHEMBIOCHEM, 23 (20): (e202200413). [PMID:35997506] [10.1002/cbic.202200413] |
| 16. Cheng Bai, Wen Zhou, Shifeng Yu, Tengfei Zheng, Chaohui Wang. (2022) A surface acoustic wave-assisted micromixer with active temperature control. SENSORS AND ACTUATORS A-PHYSICAL, [PMID:] [10.1016/j.sna.2022.113833] |
| 17. Baoxia Liu, Yaoyao Zhang, Yuanqiang Hao, Xu Zhu, Yintang Zhang, Yanli Zhou, Hongliang Tan, Maotian Xu. (2022) All-in-One Luminescent Lanthanide Coordination Polymer Nanoprobe for Facile Detection of Protein Kinase Activity. ANALYTICAL CHEMISTRY, [PMID:35853147] [10.1021/acs.analchem.2c01307] |
| 18. Yawen Lian, Xiang Yuan, Yandan Wang, Lin Wei. (2022) Highly sensitive visual colorimetric sensor for xanthine oxidase detection by using MnO2-nanosheet-modified gold nanoparticles. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:35397450] [10.1016/j.saa.2022.121219] |
| 19. Chenhui Yin, Meng Wu, Ting Liu, Lixing Fu, Qijun Sun, Ligang Chen, Na Niu. (2022) Turn-on fluorescent inner filter effect-based B,S,N co-doped carbon quantum dots and vanadium oxide nanoribbons for α-glucosidase activity detection. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.107405] |
| 20. Pei Ting, He Yu, Wang Yaping, Song Gongwu. (2021) Fluorine-free synthesis of Ti3C2 MQDs for smartphone-based fluorescent and colorimetric determination of acetylcholinesterase and organophosphorus pesticides. MICROCHIMICA ACTA, 189 (1): (1-9). [PMID:34862575] [10.1007/s00604-021-05115-2] |
| 21. Lishuang Wang, Longshan Zhao. (2021) A novel nanocomposite optosensing sensor based on porous molecularly imprinted polymer and dual emission quantum dots for visual and high selective detection of bovine serum albumin. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2021.127843] |
| 22. Xiumei Zhuang, Yongjun Hu, Junjie Wang, Jieyu Hu, Qi Wang, Xingxing Yu. (2021) A colorimetric and SERS dual-readout sensor for sensitive detection of tyrosinase activity based on 4-mercaptophenyl boronic acid modified AuNPs. ANALYTICA CHIMICA ACTA, [PMID:34794563] [10.1016/j.aca.2021.339172] |
| 23. Fang Liu, Tiantian Lei, Yingli Zhang, Yaping Wang, Yu He. (2021) A BCNO QDs-MnO2 nanosheets based fluorescence “off-on-off” and colorimetric sensor with smartphone detector for the detection of organophosphorus pesticides. ANALYTICA CHIMICA ACTA, [PMID:34625266] [10.1016/j.aca.2021.339026] |
| 24. Can Chen, Guotong Ruan, Yujie Sun, Lili Wang, Chengwu Zhang, Jinhua Liu. (2021) In situ Cu2+-triggered wavelength-tunable fluorescent sensor for highly sensitive sensing inorganic pyrophosphatase activity and its logic gate application. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2021.130439] |
| 25. Hongzhi Lu, Shoufang Xu. (2021) CDs–MnO2–TPPS Ternary System for Ratiometric Fluorescence Detection of Ascorbic Acid and Alkaline Phosphatase. ACS Omega, [PMID:34235328] [10.1021/acsomega.1c01828] |
| 26. Liu Hui, Huang Pengcheng, Wu Fang-Ying, Ma Lihua. (2021) Colorimetric determination of acid phosphatase activity and inhibitor screening based on in situ polymerization of aniline catalyzed by gold nanoparticles. MICROCHIMICA ACTA, 188 (5): (1-10). [PMID:33822286] [10.1007/s00604-021-04799-w] |
| 27. Liu Shanshan, Zheng Sitian, Chu Jing. (2020) Cationic Polythiophene-based Colorimetric Assay for Probing the Activity of Protein Kinase A. ANALYTICAL SCIENCES, 37 (7): (1039-1043). [PMID:33250451] [10.2116/analsci.20N034] |
| 28. Xu Weiqing, Kang Yikun, Jiao Lei, Wu Yu, Yan Hongye, Li Jinli, Gu Wenling, Song Weiyu, Zhu Chengzhou. (2020) Tuning Atomically Dispersed Fe Sites in Metal–Organic Frameworks Boosts Peroxidase-Like Activity for Sensitive Biosensing. Nano-Micro Letters, 12 (1): (1-12). [PMID:34138213] [10.1007/s40820-020-00520-3] |
| 29. Saipeng Huang, Wenshuai Li, Xin Zhou, Mengyao Xie, Qing Luo, Huiyun Wen, Yane Luo, Weiming Xue. (2020) One-step synthesis of levodopa functionalized carbon quantum dots for selective detection of tyrosinase and inhibitor screening. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2020.105456] |
| 30. Guohua Qi, Dan Sun, Yu Tian, Chen Xu, Ying Zhang, Dandan Wang, Kongshuo Ma, Shuping Xu, Yongdong Jin. (2020) Fast Activation and Tracing of Caspase-3 Involved Cell Apoptosis by Combined Electrostimulation and Smart Signal-Amplified SERS Nanoprobes. ANALYTICAL CHEMISTRY, [PMID:32395992] [10.1021/acs.analchem.0c01114] |
| 31. Dan Sun, Weiqing Xu, Chongyang Liang, Wei Shi, Shuping Xu. (2020) Smart Surface-Enhanced Resonance Raman Scattering Nanoprobe for Monitoring Cellular Alkaline Phosphatase Activity during Osteogenic Differentiation. ACS Sensors, [PMID:32388973] [10.1021/acssensors.0c00428] |
| 32. Linjie Wang, Kun Ye, Jianming Pan, Hongwei Song, Xin Li, Xiangheng Niu. (2019) A catalytic reaction-based colorimetric assay of alkaline phosphatase activity based on oxidase-like MnO2 microspheres. Analytical Methods, 11 (42): (5472-5477). [PMID:] [10.1039/C9AY01772K] |
| 33. Yang Meiling, Liu Mingwang, Wu Zipeng, He Yu, Ge Yili, Song Gongwu, Zhou Jiangang. (2019) Carbon dots co-doped with nitrogen and chlorine for “off-on” fluorometric determination of the activity of acetylcholinesterase and for quantification of organophosphate pesticides. MICROCHIMICA ACTA, 186 (8): (1-8). [PMID:31363918] [10.1007/s00604-019-3715-z] |
| 34. Dandan Hu, Yufang Hu, Qingqing Zhang, Pingjian Ran, Xinda Liu, Yudi Zheng, Zhiyong Guo, Sui Wang, Di Wu. (2019) Label-Free Electrochemical Strategy for Probing TdT and Exo I Activity by Silver-Based Square Wave Voltammetry. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 166 (12): (B1028). [PMID:] [10.1149/2.1271912jes] |
| 35. Can Chen, Fenghua Geng, Yongxiang Wang, Haidong Yu, Lin Li, Sheng Yang, Jinhua Liu, Wei Huang. (2019) Design of a nanoswitch for sequentially multi-species assay based on competitive interaction between DNA-templated fluorescent copper nanoparticles, Cr3+ and pyrophosphate and ALP. TALANTA, [PMID:31450461] [10.1016/j.talanta.2019.120132] |
| 36. Yameng Han, Zhongju Ye, Fuyan Wang, Tianyu Chen, Lin Wei, Langxing Chen, Lehui Xiao. (2019) Single-particle enumeration-based ultrasensitive enzyme activity quantification with fluorescent polymer nanoparticles. Nanoscale, 11 (31): (14793-14801). [PMID:31353389] [10.1039/C9NR01817D] |
| 37. Kun Ye, Linjie Wang, Hongwei Song, Xin Li, Xiangheng Niu. (2019) Bifunctional MIL-53(Fe) with pyrophosphate-mediated peroxidase-like activity and oxidation-stimulated fluorescence switching for alkaline phosphatase detection. Journal of Materials Chemistry B, 7 (31): (4794-4800). [PMID:31389965] [10.1039/C9TB00951E] |
| 38. Xiangqian Li, Zhan Zhou, Yiping Tang, Cheng Cheng Zhang, Yuhui Zheng, Jinwei Gao, Qianming Wang. (2018) Modulation of assembly and disassembly of a new tetraphenylethene based nanosensor for highly selective detection of hyaluronidase. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2018.08.093] |
| 39. Hu Yanling, He Yu, Han Yaxue, Ge Yili, Song Gongwu, Zhou Jiangang. (2018) Poly(styrene-4-sulfonate)-protected copper nanoclusters as a fluorometric probe for sequential detection of cytochrome c and trypsin. MICROCHIMICA ACTA, 185 (8): (1-7). [PMID:30032328] [10.1007/s00604-018-2920-5] |
| 40. Mao Mi, Tian Tian, He Yu, Ge Yili, Zhou Jiangang, Song Gongwu. (2017) Inner filter effect based fluorometric determination of the activity of alkaline phosphatase by using carbon dots codoped with boron and nitrogen. MICROCHIMICA ACTA, 185 (1): (1-6). [PMID:29594532] [10.1007/s00604-017-2541-4] |
| 41. Yu Liu, Yawen Liu, Fangfang Wang, Zhigang Zhang, Haiming Hu, Lei Xiong, Junping Zheng, Hongtao Liu. (2024) A silver auto-catalyzed plasmonic enzyme-linked immunosorbent assay for colorimetric and fluorescent detection of neutrophil gelatinase associated lipocalin (NGAL). MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.111551] |
| 42. Tiantian Fu, Yu Zhang, Hongwei Cao, Ying Zhang, Xiao Guan. (2024) Effect of milling degree on vitamin B1 stability in rice: A perspective on cooking-induced component interactions. JOURNAL OF FOOD ENGINEERING, [PMID:] [10.1016/j.jfoodeng.2024.112182] |
| 43. Liwei Sun, Xu Zhang, Jiteng Zhang, Xinmeng Li, Jie Zhao, Rujian Jiang, Lingjie Song, Shifang Luan. (2024) Endogenous stimulation-driven Janus mesh with antibacterial, anti-adhesive and prohealing performances for hernia repair. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.152764] |
| 44. Yujing He, Jing Hu, Siqi Wei, Chenghui Li, Xiandeng Hou. (2024) Label-free and sensitive assay for ICP-MS determination of alkaline phosphatase activity via manganese target. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.110342] |
| 45. Yuanting Chen, Linlin Xu, Sheng Zhao, Chenfang Miao, Yuyuan Chen, Zhenzhen Wang, Feng Feng, Mingrui Lin, Shaohuang Weng. (2024) One-pot hydrothermal synthesis of silicon, nitrogen co-doped carbon dots for enhancing enzyme activity of acid phosphatase (ACP) to dopamine and for cell imaging. TALANTA, [PMID:38917549] [10.1016/j.talanta.2024.126451] |
| 46. Hong Huang, Huiru Li, Yong Zhang, Xuhan Xia, Ningwen Zhang, Haixin Fan, Longhua Guo, Yongyong Cao, Hu Pan, Ruijie Deng, Yangang Wang, Rodrigo Ledesma-Amaro, Jianguo Xu. (2025) Simultaneous Monitoring of Tyrosinase and ATP in Thick Brain Tissues Using a Single Two-Photon Fluorescent Probe. Advanced Science, [PMID:40129186] [10.1002/advs.202413220] |
| 47. Yanmei Lu, Jiayue Liu, Yufang Hu, Wenjun Dong, Caizhao Cheng, Zhihe Qing, Shun Zhang. (2024) Visual and quantitative determination of KAT Tip60 activity in circulating tumor cells using a smartphone. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2024.135827] |
| 48. Hong-Jiao Zhang, Li-Wei He, Ke-Min Dong, Song-Yuan Li, Can Luo, Jia-Qi Han, Rui Li. (2024) β-Cyclodextrin functionalized persistent luminecence nanoparticle for autofluorescence-free detection of α-glucosidase activity and its inhibitor. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112211] |
| 49. Yang Lu, Xinhua Dai, Yidi Wang, Ting Liu, Chao Liu, Xu Yan, Xiaomin Liu, Bai Li. (2025) A near infrared triggered double-shell fluorescent probe for clinical detection of alkaline phosphatase. JOURNAL OF RARE EARTHS, [PMID:] [10.1016/j.jre.2025.08.015] |
| 50. Hu Yufang, Zhang Qingqing, Xu Lihua, Wang Jiao, Rao Jiajia, Guo Zhiyong, Wang Sui. (2017) Signal-on electrochemical assay for label-free detection of TdT and BamHI activity based on grown DNA nanowire-templated copper nanoclusters. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (28): (6677-6688). [PMID:28963672] [10.1007/s00216-017-0623-0] |
| 51. Jing Tang, Jinyue Feng, Huanhua Liang, Yilan Pang, Zhijiao Tang, Zhengyi Chen, Jian Liang, Yumin Wang. (2025) Rapid and simple sensing of acetylcholinesterase and inhibition activity by utilizing a portable Raman spectrometer. TALANTA, [PMID:40222099] [10.1016/j.talanta.2025.128086] |
| 52. Dan Li, Mao Li, Zijia Huang, Xiaolong Li, Xiaoming Chen, Na Li, Yong Zhao. (2025) Ultrasensitive, online detection of endogenous H2S by a novel ratiometric fluorescent approach. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2025.137874] |
| 53. Jingjing Yin, Yuehua Wang, Shanshan Zhu, Xiaoxue Liu, Yujie Sun, Hong Yang, Yifei Ma, Jinhua Liu. (2026) HRP-induced wide wavelength-tunable in situ fluorogenic system and its immunoassay for cTnI in clinical samples. TALANTA, [PMID:41691890] [10.1016/j.talanta.2026.129511] |
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