≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
AMG PERK 44 is an orally effective, highly selective PERK inhibitor with an IC50 of 6 nM. The selectivity of AMG PERK 44 for PERK is 1000 and 160 times higher than that of GCN2 (IC50=7300 nM) and B-Raf (IC50>1000 nM), respectively. AMG PERK 44 can induce autophagy.
| Sonrisas canónicas | CC1=C(C(=C(C=C1)C(=O)C2=C(N(N(C2=O)C3=CC=CC=C3)C)C4=CC=CC=C4)N)C5=CC6=C(C=C5)N=C(C=C6)C.Cl |
|---|---|
| IUPAC Name | 4-[2-amino-4-methyl-3-(2-methylquinolin-6-yl)benzoyl]-1-methyl-2,5-diphenylpyrazol-3-one;hydrochloride |
| InChIKey | RNAKBTDDCHJCMT-UHFFFAOYSA-N |
| INCHI | 1S/C34H28N4O2.ClH/c1-21-14-18-27(31(35)29(21)25-17-19-28-24(20-25)16-15-22(2)36-28)33(39)30-32(23-10-6-4-7-11-23)37(3)38(34(30)40)26-12-8-5-9-13-26;/h4-20H,35H2,1-3H3;1H |
| Peso molecular | 561.07 |
| Reaxy-Rn | 27969561 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27969561&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
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| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 H2429044 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429045 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429046 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429047 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429048 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429049 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429050 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429051 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429052 | Certificate of Analysis | May 22, 2024 | A286749 |
| H2429179 | Certificate of Analysis | May 22, 2024 | A286749 |
| Solubilidad | Solvent:DMSO, Max Conc. mg/mL: 11.22, Max Conc. mM: 20 |
|---|---|
| Sensibilidad | Moisture sensitive |
