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AMG7703 - ≥99% , CAS No.1103523-24-5
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
AMG7703 is a selective and allosteric agonists of FFA2 ( GPR43 ), the receptor for short-chain fatty acids (SCFAs), acetate, and propionate. AMG7703 can be used to research for in inflammatory and metabolic.
In Vitro
AMG7703 (phenylacetamide 1) (30 μM) shows selectivity on FFA2 (GPR43) over FFA1 (GPR40) and FFA3 (GPR41) with in Chinese hamster ovary cells. AMG7703 (0.041, 0.123, 0.37, 1.11 μM) acts as an FFA2 allosteric agonist, activates Gα i coupled signaling pathway. AMG7703 (1, 3, 10, 30 μM) results in Gα i -dependent inhibition of lipolysis in adipocytes (3T3L1). AMG7703 (0.041, 0.123, 0.37, 1.11 μM) exhibits allosteric activity and inhibits Gα i -coupled cAMP with IC 50 values of 0.7 μM (hFFA2) and 0.96 μM (mFFA2), respectively; as for Gα q -coupled aequorin inhibition, with EC 50 s of 0.45 μM (hFFA2) and 1.27 μM (mFFA2), respectively. AMG7703 (0-1 μM) shows the positive cooperating effect of acetate and stimulates calcium mobilization in a concentration-dependent manner in CHO cell stably expressing hFFA2 and aequorin. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
Especificaciones y pureza
≥99%
Mecanismos bioquímicos y fisiológicos
AMG7703 is a selective and allosteric agonists of FFA2 ( GPR43 ), the receptor for short-chain fatty acids (SCFAs), acetate, and propionate. AMG7703 can be used to research for in inflammatory and metabolic.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
AGONIST
Pureza
≥99%
Nombres e identificadores
| Peso molecular | 294.80 |
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Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 100 mg/mL (339.21 mM; ultrasonic and warming and heat to 60°C) |
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Calculadoras de soluciones
Reseñas
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