Amidepsine A, CAS No.169181-28-6

CAS: 169181-28-6 Cat. No.: A276288 Peso molecular: 567.54

GRADE & PURITY ≥95%

Descripción general

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Product Name

Amidepsine A, CAS No.169181-28-6

Sinónimos

2-[[4-[4-(2, 4-Dimethoxy-6-methylbenzoyl)oxy-2-hydroxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoyl]amino]propanoicacid

Especificaciones y pureza

≥95%

Mecanismos bioquímicos y fisiológicos

DGAT inhibitor (IC 50 values are 10.2 and 15.5 μM for rat liver microsomes and Raji cells respectively). Amidepsine D analog. May show antiobesogenic and antidiabetic effects in vivo.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

CAS

169181-28-6

Tipo de molécula

Enzyme

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Desiccated

Enviado en

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Clase Depsides and depsidones

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Clase: Depsides and depsidones
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Depsides and depsidones
• Alternative Parents: Hippuric acids N-acyl-alpha amino acids o-Hydroxybenzoic acid esters P-methoxybenzoic acids and derivatives O-methoxybenzoic acids and derivatives Alanine and derivatives Salicylamides Phenol esters Dimethoxybenzenes o-Toluamides Benzoyl derivatives Anisoles Phenoxy compounds Meta cresols 1-hydroxy-2-unsubstituted benzenoids 1-hydroxy-4-unsubstituted benzenoids Alkyl aryl ethers Vinylogous acids Carboxylic acid esters Secondary carboxylic acid amides Monocarboxylic acids and derivatives Carboxylic acids Hydrocarbon derivatives Organonitrogen compounds Organic oxides Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Depside backbone - Hippuric acid or derivatives - Hippuric acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - O-hydroxybenzoic acid ester - Alanine or derivatives - O-methoxybenzoic acid or derivatives - P-methoxybenzoic acid or derivatives - Alpha-amino acid or derivatives - Benzoate ester - Phenol ester - M-dimethoxybenzene - Dimethoxybenzene - Salicylamide - Salicylic acid or derivatives - O-toluamide - Toluamide - Benzoic acid or derivatives - Benzamide - Phenol ether - Methoxybenzene - M-cresol - Phenoxy compound - Anisole - Benzoyl - Phenol - 1-hydroxy-4-unsubstituted benzenoid - Alkyl aryl ether - 1-hydroxy-2-unsubstituted benzenoid - Toluene - Benzenoid - Monocyclic benzene moiety - Vinylogous acid - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid ester - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Carboxylic acid - Ether - Organic oxygen compound - Carbonyl group - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as depsides and depsidones. These are polycyclic compounds that is either a polyphenolic compound composed of two or more monocyclic aromatic units linked by an ester bond (depside), or a compound containing the depsidone structure (depsidone).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y