Information
Antipyrine Antipyrine (Phenazone) is an analgesic and antipyretic agent; selective COX-3 inhibitor.
In vitro
Antipyrine is an analgesic and antipyretic.
In vivo
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:≥99%
| ALogP | 0.4 |
|---|
| Isómeros SMILES | CC1=CC(=O)N(N1C)C2=CC=CC=C2 |
|---|---|
| WGK Alemania | 1 |
| RTECS | CD2450000 |
| Peso molecular | 188.23 |
| Beilstein | 157775 |
| Reaxy-Rn | 157775 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=157775&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Índice de refracción | 1.5697 |
|---|---|
| Punto de ebullición (°C) | 319°C |
| Punto de fusión (°C) | 114°C |
| 1. Shilong Jiang, Song Cheng, Jiashun Cao, Cailiang Yue, Jianglei Xiong, Cong Jiang, Hongzhan Cai, Jianhua Wu. (2023) Monodispersed Co-N3 loaded carbon nitride mediated peroxymonosulfate activation for rapid degradation of trace urea via singlet oxygen. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.147526] |
| 2. Yuqiong Gao, Han Ning, Yanyan Rao, Kexuan Li, Chaole Zeng, Naiyun Gao. (2023) Efficient elimination of phenazone by an electro-assisted Fe3+-EDDS/PS process at neutral pH: Kinetics, mechanistic insights and toxicity evaluation. CHEMOSPHERE, [PMID:37028723] [10.1016/j.chemosphere.2023.138598] |
| 3. Wanbao Wu, Yihong Liang, Deping Li, Yiyang Bo, Dong Wu, Lijie Ci, Mingyu Li, Jiaheng Zhang. (2022) A Competitive Solvation of Ternary Eutectic Electrolytes Tailoring the Electrode/Electrolyte Interphase for Lithium Metal Batteries. ACS Nano, [PMID:36040142] [10.1021/acsnano.2c05016] |
| 4. Chen Junyang, Xiang Pan, Duro-Castano Aroa, Cai Huawei, Guo Bin, Liu Xiqin, Yu Yifan, Lui Su, Luo Kui, Ke Bowen, Ruiz-Pérez Lorena, Gong Qiyong, Tian Xiaohe, Battaglia Giuseppe. (2025) Rapid amyloid-β clearance and cognitive recovery through multivalent modulation of blood–brain barrier transport. Signal Transduction and Targeted Therapy, 10 (1): (1-12). [PMID:41052971] [10.1038/s41392-025-02426-1] |
| 5. Fu Zeng, Lian Huang, Ding Han, Renjie Liu, Kongjia Zhang, Yuwen Su, Tong Su, Yarong Lin, Jianbo Xiu. (2025) An Improved SHANEL Procedure for Clearing and Staining Brain Tissue from Multiple Species. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 26 (8): (3569). [PMID:40332069] [10.3390/ijms26083569] |
